Pulmonary granulomas confirmed in Blau syndrome using TBLC specimens Provisionally Accepted
Yasuo Shimizu
Akihiro Takemasa
Kazuyuki Ishida
Seiji Niho- 1Dokkyo Medical University School of Medicine, Japan
Blau syndrome (BS), is an autoinflammatory granulomatosis disease characterized by a distinct triad of skin, joint, and eye disorders similar to those of sarcoidosis, but the lung involvement frequently observed in sarcoidosis are rare. Granulomas from patients with BS displayed a distinct morphology indicating an exuberant chronic inflammatory response. Patients with BS may have granulomatous lung lesions, which require early diagnosis. To determine whether therapeutic intervention is needed for lung lesions, examining transbronchial lung cryobiopsy specimens and accumulating cases of BS with lung involvement could be contributed to improving BS management in the future.
Keywords: Nod2, Cryobiopsy, Lung, Sarcoidosis, granulomas
Received: 01 Feb 2024;
Accepted: 20 May 2024.
Copyright: © 2024 Shimizu, Kushima, Tanaka, Takemasa, Ishida and Niho. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Prof. Yasuo Shimizu, Dokkyo Medical University School of Medicine, Mibu, Japan