AUTHOR=Silva Lorena C. F. , Almeida Gabriel M. F. , Assis Felipe L. , Albarnaz Jonas D. , Boratto Paulo V. M. , Dornas Fábio P. , Andrade Ketyllen R. , La Scola Bernard , Kroon Erna G. , da Fonseca Flávio G. , Abrahão Jônatas S. TITLE=Modulation of the expression of mimivirus-encoded translation-related genes in response to nutrient availability during Acanthamoeba castellanii infection JOURNAL=Frontiers in Microbiology VOLUME=6 YEAR=2015 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2015.00539 DOI=10.3389/fmicb.2015.00539 ISSN=1664-302X ABSTRACT=
The complexity of giant virus genomes is intriguing, especially the presence of genes encoding components of the protein translation machinery such as transfer RNAs and aminoacyl-tRNA-synthetases; these features are uncommon among other viruses. Although orthologs of these genes are codified by their hosts, one can hypothesize that having these translation-related genes might represent a gain of fitness during infection. Therefore, the aim of this study was to evaluate the expression of translation-related genes by mimivirus during infection of