TY - JOUR AU - Smeekens, S. P. AU - van de Veerdonk, F. L. AU - Netea, M. G. PY - 2016 M3 - Review TI - An Omics Perspective on Candida Infections: Toward Next-Generation Diagnosis and Therapy JO - Frontiers in Microbiology UR - https://www.frontiersin.org/articles/10.3389/fmicb.2016.00154 VL - 7 SN - 1664-302X N2 - Candida species can cause severe infections associated with high morbidity and mortality. Therefore, it is essential to gain more insight into the anti-fungal host defense response. The advent of omics technology and development of advanced systems biology tools has permitted to approach this in an unbiased and quantitative manner. This review summarizes the insights gained on anti-Candida immunity from genetic-, transcriptome-, proteome-, metabolome-, microbiome-, mycobiome-, and computational systems biology studies and discusses practical aspects and future perspectives. ER -