Editorial: Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles, and Environmental Adaptations

The phylum Actinobacteria composes a diverse group of Gram-positive bacteria with high G + C content, which are abundant in soils and present in various special and extreme habitats. Actinobacteria have made a significant contribution to the health and well-being of people throughout the world (Demain and Sanchez, 2009). However, the increasing emergence of new diseases and pathogens, and the antibiotic resistance question in recent years have caused a resurgence of interest in finding new biologically active compounds for drug discovery. Thus, previously unexplored ecological niches and regions in the world have been pursued as sources of novel actinobacteria and antibiotics and other useful biologically active agents (Tiwari and Gupta, 2012). With Prof. William C. Campbell and Satoshi Omura winning the Nobel Prize in Physiology or Medicine in 2015 for their discovery of Avermectin, the discovery of new antibiotics from actinobacteria is expected to enter a new golden age.


Actinobacteria in Special and Extreme Habitats: Diversity, Function Roles, and Environmental Adaptations
The phylum Actinobacteria composes a diverse group of Gram-positive bacteria with high G + C content, which are abundant in soils and present in various special and extreme habitats. Actinobacteria have made a significant contribution to the health and well-being of people throughout the world (Demain and Sanchez, 2009). However, the increasing emergence of new diseases and pathogens, and the antibiotic resistance question in recent years have caused a resurgence of interest in finding new biologically active compounds for drug discovery. Thus, previously unexplored ecological niches and regions in the world have been pursued as sources of novel actinobacteria and antibiotics and other useful biologically active agents (Tiwari and Gupta, 2012). With Prof. William C. Campbell and Satoshi Omura winning the Nobel Prize in Physiology or Medicine in 2015 for their discovery of Avermectin, the discovery of new antibiotics from actinobacteria is expected to enter a new golden age.
Actinobacteria have been isolated from diverse ecosystems, including alkaline saline soil, marine sponges, and deep sea sediments, hot springs, guts, and medicinal plants. They have broad applications potential in agriculture and environmental protection apart from antibiotic production due to their diverse ecological functions. During the last few decades, actinobacterial resource research has focused on special habitats and extreme environments; however, due to the limitations of isolation and cultivation methods, our knowledge of the diversity and ecology of extremophilic actinobacteria is at best fragmentary (Bull, 2011). Recent advances in microbial cultivation, next generation sequencing (NGS) technologies and -omics (metagenomics, metaproteomics etc) methods have greatly contributed to the rapid advancement of our understanding of actinobacterial diversity from special and extreme habitats (Qin et al., 2012;Hamedi et al., 2013;Orsi et al., 2016). Still, the physiological functions of actinobacteria and their environmental interactions await further investigation.
We proposed this research topic to highlight the current advances and knowledge related to actinobacteria from extreme environments. In this Research Topic e-book "Actinobacteria in special and extreme habitats: diversity, function roles and environmental adaptations" we collected 17 articles, including 4 reviews and 13 original articles that focus on actinobacterial species diversity from different special and extreme habitats, as well as the bioactive secondary metabolites, functional genes and potential ecological functions of actinobacteria. We are grateful to all authors who have submitted contributions to this research topic.
Actinobacteria in extreme habitats represent not only extensive taxonomic diversity, but also high genetic diversity of their biosynthetic pathways for synthesizing novel biological compounds. Mohammadipanah and Wink review the diversity and biotechnological potential of actinobacteria from arid and desert habitats. The article by Shivlata and Satyanarayana also reviews the taxonomic diversity of thermophilic and alkaliphilic actinobacteria, and discusses their potential applications in industry, agriculture and biotechnology. We are delighted to present this research topic in Frontiers in Microbiology. We hope that this e-book will be interesting and useful to the readers of the journal and broaden the knowledge of actinobacteria in harsh environments. The information available above is promising but still limited. In the future, the application of innovative isolation and cultivation techniques, and -omics methods will undoubtedly unveil more unexpected and exciting aspects of actinobacteria in special and extreme habitats, and illuminate especially their ecophysiological function in nature.

AUTHOR CONTRIBUTIONS
SQ organized this topic and wrote the editorial article. WL also wrote the editorial article. SD and WH are the co-editors of the topic and discussed the writing.