AUTHOR=Liu Wenfeng , Rochat Tatiana , Toffano-Nioche Claire , Le Lam Thao Nguyen , Bouloc Philippe , Morvan Claire TITLE=Assessment of Bona Fide sRNAs in Staphylococcus aureus JOURNAL=Frontiers in Microbiology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2018.00228 DOI=10.3389/fmicb.2018.00228 ISSN=1664-302X ABSTRACT=
Bacterial regulatory RNAs have been extensively studied for over a decade, and are progressively being integrated into the complex genetic regulatory network. Transcriptomic arrays, recent deep-sequencing data and bioinformatics suggest that bacterial genomes produce hundreds of regulatory RNAs. However, while some have been authenticated, the existence of the others varies according to strains and growth conditions, and their detection fluctuates with the methodologies used for data acquisition and interpretation. For example, several small RNA (sRNA) candidates are now known to be parts of UTR transcripts. Accurate annotation of regulatory RNAs is a complex task essential for molecular and functional studies. We defined