Corrigendum: Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective
- 1Department of Pathology, University of Cambridge, Cambridge, United Kingdom
- 2School of Life Sciences, University of Warwick, Coventry, United Kingdom
by Greene, N. P., Kaplan, E., Crow, A., and Koronakis, V. (2018). Front. Microbiol. 9:950. doi: 10.3389/fmicb.2018.00950
In the original article, there was a mistake in Figure 6 as published. The labels “ATP hydrolysis” and “ATP binding” were inverted; the corrected Figure 6 appears below. The error does not change the scientific conclusions of the article in any way.
Figure 6. Mechanotransmission mechanism of MacB. ATP binding and hydrolysis cause large, transmembrane conformational changes in MacB structure. Rather than transporting substrates across the inner membrane, MacB-like proteins coordinate reversible dimerization of their NBDs with periplasmic conformational changes. TEP-forming MacB homologs use periplasmic conformational change to drive substrates across the bacterial outer membrane via TolC-like exit ducts. MacB homologs that do not form TEPs are proposed to use similar motions during lipoprotein trafficking and transmembrane signaling. Adapted from Crow et al. (2017).
The original article has been updated.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Keywords: antibiotic resistance, tripartite efflux pump, MacB, mechanotransmission, ABC transporter, lantibiotic, membrane protein, antimicrobial resistance
Citation: Greene NP, Kaplan E, Crow A and Koronakis V (2018) Corrigendum: Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective. Front. Microbiol. 9:2318. doi: 10.3389/fmicb.2018.02318
Received: 13 August 2018; Accepted: 11 September 2018;
Published: 28 September 2018.
Edited and reviewed by: Rustam Aminov, University of Aberdeen, United Kingdom
Copyright © 2018 Greene, Kaplan, Crow and Koronakis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Vassilis Koronakis, email@example.com