TY - JOUR AU - Trojanowski, Damian AU - Hołówka, Joanna AU - Zakrzewska-Czerwińska, Jolanta PY - 2018 M3 - Review TI - Where and When Bacterial Chromosome Replication Starts: A Single Cell Perspective JO - Frontiers in Microbiology UR - https://www.frontiersin.org/articles/10.3389/fmicb.2018.02819 VL - 9 SN - 1664-302X N2 - Bacterial chromosomes have a single, unique replication origin (named oriC), from which DNA synthesis starts. This study describes methods of visualizing oriC regions and the chromosome replication in single living bacterial cells in real-time. This review also discusses the impact of live cell imaging techniques on understanding of chromosome replication dynamics, particularly at the initiation step, in different species of bacteria. ER -