AUTHOR=Obenoskey Jesseeca , Lane Dakota R. , Atkin Audrey L. , Kebaara Bessie W. TITLE=Immunity of the Saccharomyces cerevisiae SSY5 mRNA to nonsense-mediated mRNA decay JOURNAL=Frontiers in Molecular Biosciences VOLUME=1 YEAR=2014 URL=https://www.frontiersin.org/journals/molecular-biosciences/articles/10.3389/fmolb.2014.00025 DOI=10.3389/fmolb.2014.00025 ISSN=2296-889X ABSTRACT=
The nonsense-mediated mRNA decay (NMD) pathway is a specialized pathway that triggers the rapid degradation of select mRNAs. Initially, identified as a pathway that degrades mRNAs with premature termination codons, NMD is now recognized as a pathway that also regulates some natural mRNAs. Since natural mRNAs do not typically contain premature termination codons, these mRNAs contain features that target them to NMD. In