AUTHOR=Cham Kai Lin , Soga Tomoko , Parhar Ishwar S. TITLE=Expression of RING Finger Protein 38 in Serotonergic Neurons in the Brain of Nile Tilapia, Oreochromis niloticus JOURNAL=Frontiers in Neuroanatomy VOLUME=12 YEAR=2018 URL=https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2018.00109 DOI=10.3389/fnana.2018.00109 ISSN=1662-5129 ABSTRACT=
Serotonin (5-hydroxytryptamine, 5-HT) is one of the major neurotransmitters, modulating diverse behaviours and physiological functions. Really interesting new gene (RING) finger protein 38 (RNF38) is an E3 ubiquitin ligase whose function remains unclear. A recent study has shown a possible regulatory relationship between RNF38 and the 5-HT system. Therefore, to gain insight into the role of RNF38 in the central 5-HT system, we identified the neuroanatomical location of 5-HT positive cells and investigated the relationship between RNF38 and the 5-HT system in the brain of the Nile tilapia,