@ARTICLE{10.3389/fncir.2013.00160, AUTHOR={Asrican, Brent and Augustine, George J and Berglund, Ken and Chen, Susu and Chow, Nicholas and Deisseroth, Karl and Feng, Guoping and Gloss, Bernd and Hira, Riichiro and Hoffmann, Carolin and Kasai, Haruo and Katarya, Malvika and Kim, Jinsook and Kudolo, John and Lee, Liming and Lo, Shun-Qiang and Mancuso, James and Matsuzaki, Masanori and Nakajima, Ryuichi and Qui, Li and Tan, Gregory and Tang, Yanxia and Ting, Jonathan T. and Tsuda, Sachiko and Wen, Lei and Zhang, Xuying and Zhao, Shengli}, TITLE={Next-generation transgenic mice for optogenetic analysis of neural circuits}, JOURNAL={Frontiers in Neural Circuits}, VOLUME={7}, YEAR={2013}, URL={https://www.frontiersin.org/articles/10.3389/fncir.2013.00160}, DOI={10.3389/fncir.2013.00160}, ISSN={1662-5110}, ABSTRACT={Here we characterize several new lines of transgenic mice useful for optogenetic analysis of brain circuit function. These mice express optogenetic probes, such as enhanced halorhodopsin or several different versions of channelrhodopsins, behind various neuron-specific promoters. These mice permit photoinhibition or photostimulation both in vitro and in vivo. Our results also reveal the important influence of fluorescent tags on optogenetic probe expression and function in transgenic mice.} }