Frontiers in Neural Circuits Mini Review Provisionally Accepted
Haruki Takeuchi
Ai Nakashima- 1The University of Tokyo, Japan
The brain constructs spatially organized sensory maps to represent sensory information. The formation of sensory maps has traditionally been thought to depend on synchronous neuronal activity. However, recent evidence from the olfactory system suggests that cell type-specific temporal patterns of spontaneous activity play an instructive role in shaping the olfactory glomerular map. These findings challenge traditional views and highlight the importance of investigating the spatiotemporal dynamics of neural activity to understand the development of complex neural circuits. This review discusses the implications of new findings in the olfactory system and outlines future research directions.
Keywords: Olfactory Map, Olfactory sensory neurons, axonal projection, odorant receptors, G-proteincoupled receptors, agonist-independent activity, cAMP
Received: 30 Mar 2024;
Accepted: 30 Apr 2024.
Copyright: © 2024 Takeuchi and Nakashima. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Mx. Haruki Takeuchi, The University of Tokyo, Bunkyo, Japan
Dr. Ai Nakashima, The University of Tokyo, Bunkyo, Japan