TY - JOUR AU - Murate, Kenichiro AU - Mizutani, Yasuaki AU - Maeda, Toshiki AU - Nagao, Ryunosuke AU - Kikuchi, Kouichi AU - Shima, Sayuri AU - Niimi, Yoshiki AU - Ueda, Akihiro AU - Ito, Shinji AU - Mutoh, Tatsuro PY - 2018 M3 - Case Report TI - A Patient With Thiamine Deficiency Exhibiting Muscle Edema Suggested by MRI JO - Frontiers in Neurology UR - https://www.frontiersin.org/articles/10.3389/fneur.2018.01083 VL - 9 SN - 1664-2295 N2 - Myalgia is sometimes observed in patients with thiamine-deficiency neuropathy. However, the detailed mechanism(s) underlying muscular manifestations have been poorly elucidated. We herein report a possible patient with thiamine-deficiency neuropathy exhibiting muscle weakness and myalgia in lower limbs. The patient exhibited abnormal muscle signal intensities on MRI corresponding to the site of myalgia. After thiamine replacement therapy, rapid improvement of clinical symptoms and abnormal MRI findings were observed. Muscle MRI findings in this case implicated the possible mechanism of myalgia observed in patients with thiamine deficiency neuropathy. ER -