AUTHOR=Jin Yang , Sun Li Hua , Yang Wei , Cui Ran Ji , Xu Song Bai 

TITLE=The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders

JOURNAL=Frontiers in Neurology

VOLUME=Volume 10 - 2019

YEAR=2019

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2019.00515

DOI=10.3389/fneur.2019.00515

ISSN=1664-2295

ABSTRACT=Neuroimmune system plays a crucial role in the regulation of mood disorders. Moreover, recent studies show that brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is a key regulator in the neuroimmune axis. However, the potential mechanism of BDNF action in the neuroimmune axis regulation of mood disorders remains unclear. Therefore, in this review we focus on the recent progress of BDNF in influencing mood disorders by participating in alterations of the neuroimmune axis. It may provide evidence for future studies in this field.