%A Wang,Jiejun %A Jia,Luqiong %A Yang,Xinjian %A Jia,Xuecang %A Liu,Jian %A Liu,Peng %A Miao,Zefeng %A Zhang,Ying %A Tian,Zhongbin %A Wang,Kun %A Wang,Zhongxiao %A Zhang,Yisen %A Lv,Ming %D 2019 %J Frontiers in Neurology %C %F %G English %K Outcome,Presenting symptoms,endovascular treatment,Symptomatic patients,Vertebrobasilar dolichoectasia %Q %R 10.3389/fneur.2019.00610 %W %L %M %P %7 %8 2019-June-13 %9 Original Research %# %! Endovascular treatment for VBD %* %< %T Outcomes in Symptomatic Patients With Vertebrobasilar Dolichoectasia Following Endovascular Treatment %U https://www.frontiersin.org/articles/10.3389/fneur.2019.00610 %V 10 %0 JOURNAL ARTICLE %@ 1664-2295 %X Objective: To evaluate whether the presenting symptoms of VBD predict outcomes following endovascular treatment.Methods: We retrospectively reviewed our institutional clinical database and identified 22 patients (all men; mean age: 52.6 years, range: 11–73 years) with a diagnosis of VBD, who underwent endovascular treatment from January 2010 to December 2017.Results: After analyzing the clinical and imaging data, we evaluated data for 22 symptomatic patients with VBD. At the time of VBD diagnosis, 13 patients (59%) had compressive symptoms, four (18%) had hemorrhagic symptoms, and five (23%) had ischemic symptoms. Nine of the 22 patients (41%), who presented with hemorrhagic and ischemic symptoms, achieved a satisfactory clinical and/or digital subtraction angiography imaging outcome after endovascular treatment. However, of the 13 patients who presented with compressive symptoms, seven (54%, 7/13) died from severe brainstem compression during follow-up; furthermore, magnetic resonance imaging showed worsening of the mass effect in eight patients with compressive symptoms (62%, 8/13).Conclusions: VBD is considered a challenging lesion without an ideal treatment modality. Endovascular treatment of VBD in patients presenting with compressive symptoms at diagnosis may not be beneficial. However, long-term outcomes following endovascular treatment may be acceptable in patients with non-compressive symptoms at diagnosis compared with those with compressive symptoms.