AUTHOR=Wei Wei , Song Chong , Li Xuqin , Jin Dianshi 

TITLE=Utility of CT Perfusion Imaging in Patients With Vertebral Artery Stenosis Treated With Balloon Expandable Stent

JOURNAL=Frontiers in Neurology

VOLUME=Volume 12 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2021.650887

DOI=10.3389/fneur.2021.650887

ISSN=1664-2295

ABSTRACT=Objective to investigate the clinical value of CT perfusion (CTP) imaging in vertebral artery stenosis stenting, so as to provide the basis for preoperative and postoperative evaluation. 97 patients with vertebral artery stenosis were accepted endovascular stenting between Jan 2016 to Jan 2020, CT angiography, Digital Substraction Angiography and CTP were performed pre-operation and post-operation. The cerebral blood volume (CBV), cerebral blood flow (CBF) and mean transmit time (MTT) between the health and affected sides were analyzed statistically, and also evaluate the imaging results of pre- and post-operation. The stenosis was relieved by endovascular stents in all 97 patients without serious complications. The abnormal perfusion was observed in 66 patients (68%). The differences in CBF and MTT between the diseased side and healthy side were statistically significant (P<0.05). Compared with the preoperative imaging, the postoperative CTP were improved in 59 patients (89%). The differences in CBF and MTT between pre-operation and post-operation were statistically significant (P<0.05). But there was no significant difference in CBV. CTP can sensitively reflect the perfusion of brain, and can also be used for preoperative and postoperative evaluation of vertebral artery stenting. It may be helpful to adequate indicator of vertebral artery stenosis stent surgery.