%A Chenausky,Karen V. %A Norton,Andrea C. %A Schlaug,Gottfried %D 2017 %J Frontiers in Human Neuroscience %C %F %G English %K autism,Speech Therapy,intonation,AMMT,minimally verbal,speech development %Q %R 10.3389/fnhum.2017.00426 %W %L %M %P %7 %8 2017-September-04 %9 Original Research %+ Prof Gottfried Schlaug,Music, Neuroimaging, and Stroke Recovery Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center,Boston, MA, United States,gschlaug@gmail.com %+ Prof Gottfried Schlaug,Department of Neurology, Harvard Medical School,Boston, MA, United States,gschlaug@gmail.com %# %! AMMT in a more verbal child with ASD %* %< %T Auditory-Motor Mapping Training in a More Verbal Child with Autism %U https://www.frontiersin.org/articles/10.3389/fnhum.2017.00426 %V 11 %0 JOURNAL ARTICLE %@ 1662-5161 %X We tested the effect of Auditory-Motor Mapping Training (AMMT), a novel, intonation-based treatment for spoken language originally developed for minimally verbal (MV) children with autism, on a more-verbal child with autism. We compared this child’s performance after 25 therapy sessions with that of: (1) a child matched on age, autism severity, and expressive language level who received 25 sessions of a non-intonation-based control treatment Speech Repetition Therapy (SRT); and (2) a matched pair of MV children (one of whom received AMMT; the other, SRT). We found a significant Time × Treatment effect in favor of AMMT for number of Syllables Correct and Consonants Correct per stimulus for both pairs of children, as well as a significant Time × Treatment effect in favor of AMMT for number of Vowels Correct per stimulus for the more-verbal pair. Magnitudes of the difference in post-treatment performance between AMMT and SRT, adjusted for Baseline differences, were: (a) larger for the more-verbal pair than for the MV pair; and (b) associated with very large effect sizes (Cohen’s d > 1.3) in the more-verbal pair. Results hold promise for the efficacy of AMMT for improving spoken language production in more-verbal children with autism as well as their MV peers and suggest hypotheses about brain function that are testable in both correlational and causal behavioral-imaging studies.