AUTHOR=Kandemir Basak , Caglayan Berrak , Hausott Barbara , Erdogan Burcu , Dag Ugur , Demir Ozlem , Sogut Melis S. , Klimaschewski Lars , Kurnaz Isil A. 

TITLE=Pea3 transcription factor promotes neurite outgrowth

JOURNAL=Frontiers in Molecular Neuroscience

VOLUME=7

YEAR=2014

URL=https://www.frontiersin.org/journals/molecular-neuroscience/articles/10.3389/fnmol.2014.00059

DOI=10.3389/fnmol.2014.00059

ISSN=1662-5099

ABSTRACT=<p>Pea3 subfamily of E–twenty six transcription factors consist of three major -exhibit branching morphogenesis, the function of Pea3 family in nervous system development and regeneration is only beginning to unfold. In this study, we provide evidence that Pea3 can directs neurite extension and axonal outgrowth in different model systems, and that Serine 90 is important for this function. We have also identified <italic>neurofilament-L</italic> and <italic>neurofilament-M</italic> as two putative novel targets for Pea3.</p>