AUTHOR=Gaertner Kelly M. , Caldwell Stephen H. , Rahma Osama E. 

TITLE=A Case of Retinal Tear Associated with Use of Sorafenib

JOURNAL=Frontiers in Oncology

VOLUME=4

YEAR=2014

URL=https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2014.00196

DOI=10.3389/fonc.2014.00196

ISSN=2234-943X

ABSTRACT=<p>Inhibition of angiogenesis is a target in the treatment of a variety of malignancies. Sorafenib is an oral inhibitor of multiple tyrosine kinases involved in tumor angiogenesis. A related case of ophthalmologic toxicity has been reported with another vascular endothelial growth factor receptor inhibitor, sunitinib. We report the first case of retinal tear possibly associated with sorafenib.</p>