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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Pediatr. | doi: 10.3389/fped.2019.00098

Propofol Sedation by Pediatric Gastroenterologists for Endoscopic Procedures: A retrospective analysis

  • 1The Ruth and Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Israel
  • 2Rambam Health Care Campus, Israel

Background: There is a substantial literature on the favorable outcome of propofol administration by non-anesthesiologists for endoscopy in adults; however, very few data are currently available on propofol sedation by pediatric gastroenterologists. Aims: to evaluate the safety of propofol sedation by pediatric gastroenterologists.
Methods: A retrospective chart review of all children who were sedated by pediatric gastroenterologists in three Northern Israeli hospitals over a four year period Demographic and medical characteristics and any data regarding the procedure were extracted from patient's records. The main outcome measurements were procedure completion and reported adverse events.
Results: Overall, 1214 endoscopic procedures for were performed during this period. Complete data was available for 1190 procedures. All children sedated by pediatric gastroenterologists were classified as ASA I or II. Propofol dosage (in mg/kg) inversely correlated with patient age. The younger the child the higher the dose needed to reach a satisfactory level of sedation (r=-0.397,p<0.001). The addition of fentanyl significantly decreased propofol dosage needed to provide optimal sedation, p <0.001. Nine (0.7%) reversible adverse events were reported. All the procedures were successfully completed and all patients were discharged home.
Conclusions: We conclude that our approach is safe in children as it is in adults and can be implemented for children with ASA I, II.

Keywords: sedation, Endoscopies, Children, Safety, nonanesthesiologist administered propofol

Received: 04 Aug 2018; Accepted: 04 Mar 2019.

Edited by:

Jorge A. Dias, Gastrenterologia, Centro Hospitalar de São João, Portugal

Reviewed by:

Corentin Babakissa, Université de Sherbrooke, Canada
Javier Martin De Carpi, Hospital Sant Joan de Déu Barcelona, Spain  

Copyright: © 2019 Khalila, Shavit and Shaoul. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Ron Shaoul, Rambam Health Care Campus, Haifa, Haifa, Israel,