@ARTICLE{10.3389/fped.2021.656768, AUTHOR={Kurz, Herbert and Gombala, Tomas}, TITLE={Multisystem Inflammatory Syndrome in Children (MIS-C)—A Case Series in December 2020 in Vienna, Austria}, JOURNAL={Frontiers in Pediatrics}, VOLUME={9}, YEAR={2021}, URL={https://www.frontiersin.org/articles/10.3389/fped.2021.656768}, DOI={10.3389/fped.2021.656768}, ISSN={2296-2360}, ABSTRACT={MIS-C is a novel clinical syndrome in children and adolescents, was first encountered in the spring of 2020 as a post COVID-19 multisystem inflammatory syndrome. The highest number of SARS-CoV-2 infections in Austria were registered in November 2020. In December 2020, eight patients with MIS-C were hospitalized at the pediatric department of Klinik Donaustadt, a large municipal hospital in Vienna. Six of the patients needed pediatric intensive care. As we lack any international consensus on the diagnosis and treatment of this severe complication, we used a multidisciplinary approach. The purpose was to establish an internal standard for maximizing the efficacy and safety of treatment, and standardizing the clinical management of this disease.} }