Corrigendum: Single nucleotide polymorphisms interactions of the surfactant protein genes associated with respiratory distress syndrome susceptibility in preterm infants
Shaili Amatya1 
Meixia Ye2 
Lili Yang3 
Chintan K. Gandhi1 
Rongling Wu4 Beth Nagourney5 
Joanna Floros1,6*
- 1Department of Pediatrics, Center for Host Defense, Inflammation, and Lung Disease (CHILD) Research, Pennsylvania State University College of Medicine, Hershey, PA, United States
- 2Center for Computational Biology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing, China
- 3School of First Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing, China
- 4Public Health Science, Pennsylvania State University College of Medicine, Hershey, PA, United States
- 5Albert Einstein College of Medicine, New York, NY, United States
- 6Obstetrics and Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, United States
A Corrigendum on
By Amatya S, Ye M, Yang L, Gandhi CK, Wu R, Nagourney B and Floros J. (2021). Front. Pediatr. 9: 682160. doi: 10.3389/fped.2021.682160
In the published article, there was an error in Figure 2 pertaining to SNP2 and SNP3 and is limited to the last 3 lines shown under each of these SNPs. The corrected Figure 2 appears below.
In the published article, there was an error in the Results section, subsection “Association of SFTP SNP-SNP Interaction With RDS”, subsection “Three SNP model intergenic interactions”, where “SNP 3- 1059047” should be “SNP3- 1059057”.
This sentence previously stated:
“This figure depicts an interaction among three SNPs of SFTPA1 and SFTPA2. In this intergenic interaction, the additive effect of SNP1, rs17886395, G variant that codes for alanine interacts with SNP2 (rs1059047) and SNP3 (rs1059047) of SFTPA1 in a dominant effect.”
The corrected sentence appears below:
“This figure depicts an interaction among three SNPs of SFTPA1 and SFTPA2. In this intergenic interaction, the additive effect of SNP1, rs17886395, G variant that codes for alanine interacts with SNP2 (rs1059047) and SNP3 (rs1059057) of SFTPA1 in a dominant effect.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Figure 2. Intergenic three SNP interaction and RDS susceptibility. It shows the schematic presentation of SFTPA2 and SFTPA1 on the top and the arrows depict the opposite transcriptional orientation. The relative location of SNPs is shown from centromere (C) to telomere (T) and each box represents the amino acid number that includes the particular SNP. For example, AA91 denotes the rs17886395 SNP, AA19 denotes the rs1059047 SNP, and AA133 denotes the rs1059057 SNP. In this three SNP intergenic interaction, underneath the green boxes are the SNP ID and the SNPs involved. The additive effect of SNP1, rs17886395G variant that codes for alanine (highlighted in red) interacts with SNP2 and SNP3 of SFTPA1 in a dominant effect and increases risk of RDS.
Keywords: epistasis, neonatal, genetic variants, pulmonary, allele
Citation: Amatya S, Ye M, Yang L, Gandhi CK, Wu R, Nagourney B and Floros J (2022) Corrigendum: Single nucleotide polymorphisms interactions of the surfactant protein genes associated with respiratory distress syndrome susceptibility in preterm infants. Front. Pediatr. 10:1069526. doi: 10.3389/fped.2022.1069526
Received: 14 October 2022; Accepted: 3 November 2022;
Published: 30 November 2022.
Approved by: Maria Elisabetta Baldassarre, University of Bari Aldo Moro, Italy
© 2022 Amatya, Ye, Yang, Gandhi, Wu, Nagourney and Floros. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Joanna Floros jfloros@pennstatehealth.psu.edu
Specialty Section: This article was submitted to Genetics of Common and Rare Diseases, a section of the journal Frontiers in Pediatrics