Analysis of Risk Factors for Visceral Disseminated Varicella in Children Provisionally Accepted
Shuai Guo
Chaomin Wan- 1West China Second University Hospital, Sichuan University, China
Background: Visceral disseminated varicella has internal organ involvement, and complications such as encephalitis, hepatitis, and coagulation disorders threaten the patient's life. We aimed to analyze the risk factors for visceral disseminated varicella to help identify patients at high risk of visceral disseminated varicella early.
Methods: Reviewed the medical records of children hospitalized with varicella. The data covered demographics, clinical manifestations, auxiliary examinations, treatments, and outcomes. Logistic regression was used to analyze risk factors.
Results: Multivariate logistic regression analysis showed that abdominal pain (OR 20.451, 95%CI 1.637-255.548), increased CRP (OR 12.794, 95%CI 1.820-89.937), increased ALT (OR 7.453, 95%CI 1.624-34.206), and the time between onset and antiviral therapy more than 7 days (OR 12.451, 95%CI 1.569-98.810) were independent risk factors for visceral disseminated varicella.
Conclusions: Patients with varicella who have these factors need to be monitored for the risk of developing visceral disseminated varicella, and timely antiviral therapy is necessary.
Keywords: Varicella, Chickenpox, Children, Risk factors, Severe infection
Received: 27 Nov 2023;
Accepted: 09 May 2024.
Copyright: © 2024 Guo, Guo and Wan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Mx. Qin Guo, West China Second University Hospital, Sichuan University, Chengdu, China
Mx. Chaomin Wan, West China Second University Hospital, Sichuan University, Chengdu, China