TY - JOUR AU - Dangi, Arun K. AU - Sinha, Rajeshwari AU - Dwivedi, Shailja AU - Gupta, Sanjeev K. AU - Shukla, Pratyoosh PY - 2018 M3 - Review TI - Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review JO - Frontiers in Pharmacology UR - https://www.frontiersin.org/articles/10.3389/fphar.2018.00630 VL - 9 SN - 1663-9812 N2 - The present day modern formulation practices for drugs are based on newer tools and techniques toward effective utilization. The methods of antibody formulations are to be revolutionized based on techniques of cell engineering and gene editing. In the present review, we have discussed innovations in cell engineering toward production of novel antibodies for therapeutic applications. Moreover, this review deciphers the use of RNAi, ribozyme engineering, CRISPR-Cas-based techniques for better strategies for antibody production. Overall, this review describes the multidisciplinary aspects of the production of therapeutic proteins that has gained more attention due to its increasing demand. ER -