AUTHOR=Kiviniemi Antti M. , Hautala Arto J. , Karjalainen Jaana J. , Piira Olli-Pekka , Lepojärvi Samuli , Ukkola Olavi , Huikuri Heikki V. , Tulppo Mikko P. 

TITLE=Acute post-exercise change in blood pressure and exercise training response in patients with coronary artery disease

JOURNAL=Frontiers in Physiology

VOLUME=5

YEAR=2015

URL=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2014.00526

DOI=10.3389/fphys.2014.00526

ISSN=1664-042X

ABSTRACT=<p>We tested the hypothesis that acute post-exercise change in blood pressure (BP) may predict exercise training responses in BP in patients with coronary artery disease (CAD). Patients with CAD (<italic>n</italic> = 116, age 62 ± 5 years, 85 men) underwent BP assessments at rest and during 10-min recovery following a symptom-limited exercise test before and after the 6-month training intervention (one strength and 3-4 aerobic moderate-intensity exercises weekly). Post-exercise change in systolic BP (SBP) was calculated by subtracting resting SBP from lowest post-exercise SBP. The training-induced change in resting SBP was −2 ± 13 mmHg (<italic>p</italic> = 0.064), ranging from −42 to 35 mmHg. Larger post-exercise decrease in SBP and baseline resting SBP predicted a larger training-induced decrement in SBP (β = 0.46 and β = −0.44, respectively, <italic>p</italic> &lt; 0.001 for both). Acute post-exercise decrease in SBP provided additive value to baseline resting SBP in the prediction of training-induced change in resting SBP (R<sup>2</sup> from 0.20 to 0.26, <italic>p</italic> = 0.002). After further adjustments for other potential confounders (sex, age, baseline body mass index, realized training load), post-exercise decrease in SBP still predicted the training response in resting SBP (β = 0.26, <italic>p</italic> = 0.015). Acute post-exercise change in SBP was associated with training-induced change in resting SBP in patients with CAD, providing significant predictive information beyond baseline resting SBP.</p>