TY - JOUR AU - Birchler, James A. PY - 2014 M3 - Perspective TI - Interploidy hybridization barrier of endosperm as a dosage interaction JO - Frontiers in Plant Science UR - https://www.frontiersin.org/articles/10.3389/fpls.2014.00281 VL - 5 SN - 1664-462X N2 - Crosses between plants at different ploidy levels will often result in failure of endosperm development. The basis of this phenomenon has been attributed to parental gene imprinting of genes involved with endosperm development but a review of the data from maize indicates a dosage interaction between the contributions of the female gametophyte and the primary endosperm nucleus to early endosperm development. However, it is noted that parental imprinting is a non-mutational means that can alter dosage sensitive factors and therefore can contribute to this effect. Operationally, the genes determining ploidy hybridization barrier would qualify for Dobzhansky-Muller incompatibilities that prevent gene flow between species. ER -