TY - JOUR AU - Zhao, Jiantao AU - Xu, Yao AU - Ding, Qin AU - Huang, Xinli AU - Zhang, Yating AU - Zou, Zhirong AU - Li, Mingjun AU - Cui, Lu AU - Zhang, Jing PY - 2016 M3 - Original Research TI - Association Mapping of Main Tomato Fruit Sugars and Organic Acids JO - Frontiers in Plant Science UR - https://www.frontiersin.org/articles/10.3389/fpls.2016.01286 VL - 7 SN - 1664-462X N2 - Association mapping has been widely used to map the significant associated loci responsible for natural variation in complex traits and are valuable for crop improvement. Sugars and organic acids are the most important metabolites in tomato fruits. We used a collection of 174 tomato accessions composed of Solanum lycopersicum (123 accessions) and S. lycopersicum var cerasiforme (51 accessions) to detect significantly associated loci controlling the variation of main sugars and organic acids. The accessions were genotyped with 182 SSRs spreading over the tomato genome. Association mapping was conducted on the main sugars and organic acids detected by gas chromatography-mass spectrometer (GC-MS) over 2 years using the mixed linear model (MLM). We detected a total of 58 significantly associated loci (P < 0.001) for the 17 sugars and organic acids, including fructose, glucose, sucrose, citric acid, malic acid. These results not only co-localized with several reported QTLs, including fru9.1/PV, suc9.1/PV, ca2.1/HS, ca3.1/PV, ca4.1/PV, and ca8.1/PV, but also provided a list of candidate significantly associated loci to be functionally validated. These significantly associated loci could be used for deciphering the genetic architecture of tomato fruit sugars and organic acids and for tomato quality breeding. ER -