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<?covid-19-tdm?>
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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychol.</journal-id>
<journal-title>Frontiers in Psychology</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychol.</abbrev-journal-title>
<issn pub-type="epub">1664-1078</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyg.2021.664780</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychology</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>The Relationship Between Perceived Stress, State-Trait Anxiety, and Sleep Quality Among University Graduates in China During the COVID-19 Pandemic</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Liu</surname>
<given-names>Bailong</given-names>
</name>
<xref rid="c001" ref-type="corresp"><sup>&#x002A;</sup></xref>
<uri xlink:href="https://loop.frontiersin.org/people/1224825/overview"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Qiao</surname>
<given-names>Ke</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lu</surname>
<given-names>Youfeng</given-names>
</name>
</contrib>
</contrib-group>
<aff><institution>School of Marxism, Xi&#x2019;an University of Architecture and Technology</institution>, <addr-line>Xi&#x2019;an</addr-line>, <country>China</country></aff>
<author-notes>
<fn id="fn1" fn-type="edited-by">
<p>Edited by: Jason H. Huang, Baylor Scott and White Health, United States</p>
</fn>
<fn id="fn2" fn-type="edited-by">
<p>Reviewed by: Hongyu Xu, School of Medicine, Virginia Commonwealth University, United States; M. Tasdik Hasan, University of Liverpool, United Kingdom</p>
</fn>
<corresp id="c001">&#x002A;Correspondence: Bailong Liu, <email>liubailong@xauat.edu.cn</email>
</corresp>
<fn id="fn3" fn-type="other">
<p>This article was submitted to Psychology for Clinical Settings, a section of the journal Frontiers in Psychology</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>17</day>
<month>09</month>
<year>2021</year>
</pub-date>
<pub-date pub-type="collection">
<year>2021</year>
</pub-date>
<volume>12</volume>
<elocation-id>664780</elocation-id>
<history>
<date date-type="received">
<day>26</day>
<month>02</month>
<year>2021</year>
</date>
<date date-type="accepted">
<day>20</day>
<month>08</month>
<year>2021</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x00A9; 2021 Liu, Qiao and Lu.</copyright-statement>
<copyright-year>2021</copyright-year>
<copyright-holder>Liu, Qiao and Lu</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p>
</license>
</permissions>
<abstract>
<p>The study aimed to investigate the relationship among perceived stress, state-trait anxiety, and sleep quality of graduates to provide a reference for improving their psychological status and attitude adjustment of job-searching during the COVID-19 pandemic. The research was conducted in a descriptive cross-sectional online survey between May 2020 and August 2020. The data were collected from 1,200 participants by using the personal information form prepared by the researchers in line with the literature, the Perceived Stress Scale, the State-Trait Anxiety Inventory, and the Pittsburgh Sleep Quality Index (PSQI). Among the surveyed participants, 47.67% were female, and 10.92% were medical students. The mean perceived stress, state anxiety, trait anxiety, and sleep quality were moderate and found as 31.4&#x00B1;6.69, 46.67&#x00B1;5.80, 49.45&#x00B1;5.54, and 5.94&#x00B1;2.47, respectively. The detection rates of state anxiety and trait anxiety were 48.63 and 49.50%, respectively. There was no significant difference in the detection rate of state anxiety and trait anxiety among different genders and majors (<italic>p</italic> &#x003E;0.05). The detection rate of state anxiety and trait anxiety of rural family students was higher than that of urban family students (<italic>p</italic> &#x003C;0.01). The score on the PSQI was positively associated with the scores on the perceived stress, state anxiety, and trait anxiety scales (<italic>p</italic> &#x003C;0.001 for each model). Sleep quality was associated with increased perceived stress, state anxiety, and trait anxiety among graduates in China. Collectively, the study revealed the relationship between perceived stress, state-trait anxiety, and sleep quality among university graduates in China during the COVID-19 pandemic. Our results offer novel practical implications for all circles of the society to ensure students&#x2019; health under the context of the COVID-19 epidemic.</p>
</abstract>
<kwd-group>
<kwd>sleep quality</kwd>
<kwd>anxiety</kwd>
<kwd>COVID-19</kwd>
<kwd>perceived stress</kwd>
<kwd>university graduates</kwd>
</kwd-group>
<contract-num rid="cn1">2020FXM06</contract-num>
<contract-sponsor id="cn1">Excellent Project of University Student Work in Shaanxi Province</contract-sponsor>
<counts>
<fig-count count="0"/>
<table-count count="8"/>
<equation-count count="0"/>
<ref-count count="48"/>
<page-count count="7"/>
<word-count count="5427"/>
</counts>
</article-meta>
</front>
<body>
<sec id="sec1" sec-type="intro">
<title>Introduction</title>
<p>The outbreak of the COVID-19 emerged in Wuhan in December 2019 is an important public health problem (<xref ref-type="bibr" rid="ref20">Hui et al., 2020</xref>; <xref ref-type="bibr" rid="ref25">Li et al., 2020b</xref>). The WHO declared the outbreak of the novel coronavirus a global health emergency (<xref ref-type="bibr" rid="ref40">World Health Organization, 2020</xref>). The COVID-19 outbreak is expected to continue in the coming years (<xref ref-type="bibr" rid="ref2">Bao et al., 2020</xref>; <xref ref-type="bibr" rid="ref34">Paules et al., 2020</xref>). It has been reported that the new infectious diseases may cause an increase in anxiety, depression, and stress in the general population (<xref ref-type="bibr" rid="ref11">Erdo&#x011F;an and Hocao&#x011F;lu, 2020</xref>; <xref ref-type="bibr" rid="ref37">Tull et al., 2020</xref>; <xref ref-type="bibr" rid="ref23">Kim et al., 2021</xref>). Facing the COVID-19 virus, a new infectious disease has resulted in a high prevalence of mental health problems in China and other countries (<xref ref-type="bibr" rid="ref7">Chan et al., 2020</xref>; <xref ref-type="bibr" rid="ref8">Choi et al., 2020</xref>; <xref ref-type="bibr" rid="ref10">Ding et al., 2020</xref>). This increased stress in individuals, especially university students, can cause elevated anxiety levels and in turn compromise the sleep quality (<xref ref-type="bibr" rid="ref19">Huang and Zhao, 2020</xref>; <xref ref-type="bibr" rid="ref44">Zacher and Rudolph, 2020</xref>).</p>
<p>Meanwhile, the employment situation for university graduates is more and more serious. In recent years, the number of university graduates in China is gradually increasing, but the employment rate for university graduates is decreasing year by year (<xref ref-type="bibr" rid="ref27">Li et al., 2020a</xref>). In 2020, the number of university graduates in China will reach 8.74 million. With the increasing uncertainty of social employment demand, the employment situation is complex and changeable. The employment of university graduates is facing severe challenges, and employment pressure is greatly increased (<xref ref-type="bibr" rid="ref28">Liu et al., 2009</xref>; <xref ref-type="bibr" rid="ref18">Hou et al., 2019</xref>).</p>
<p>It is extremely important to determine the factors that affect the health of university graduates in combating the COVID-19 pandemic. Anxiety is a normal reaction to the novel coronavirus pneumonia and employment pressure (<xref ref-type="bibr" rid="ref45">Zhang et al., 2013</xref>; <xref ref-type="bibr" rid="ref16">Gao et al., 2019</xref>). However, some students show overwhelming anxiety reactions, which would affect their daily function and employment mentality (<xref ref-type="bibr" rid="ref47">Zhang et al., 2020</xref>). Sleep disorder is a common symptom of anxiety, which is one of the most concerned problems of university students and one of the main reasons for psychological counseling (<xref ref-type="bibr" rid="ref13">Farrah et al., 2009</xref>). It is important for university graduates to obtain quality sleep to concentrate on completing their studies and actively look for jobs. Also, quality sleep plays an important role in defending against various infections (<xref ref-type="bibr" rid="ref32">Ohrnberger et al., 2017</xref>; <xref ref-type="bibr" rid="ref4">Besedovsky and Lange, 2019</xref>).</p>
<p>Under the dual influence of COVID-19 and the increasing employment pressure, the mental health and sleep disorders of university graduates have become increasingly prominent, which have attracted the attention of all sectors of society. In this study, 1,200 university graduates were selected to analyze their perceived stress, state anxiety, trait anxiety, and sleep quality to provide a reference for improving the mental health status of university graduates.</p>
</sec>
<sec id="sec2">
<title>Participants and Methods</title>
<sec id="sec3">
<title>Participants and Sampling</title>
<p>The research was descriptive cross-sectional types. Only university graduates (aged&#x2265;18years) in Shaanxi Province who were able to provide informed consent were recruited in the study. A total of 1,200 university graduates from 11 universities in Shaanxi Province participated in the test. The survey time was from April to August 2020.</p>
</sec>
<sec id="sec4">
<title>Measurements</title>
<p>The data were collected by using the personal information form prepared by the researchers in line with the literature, the Perceived Stress Scale (PSS), the State-Trait Anxiety Inventory, and the PSQI. The study was carried out in the format of a &#x201C;Questionnaire Star&#x201D; electronic questionnaire system (Changsha Haoxing Information Technology Co., Ltd., China).</p>
</sec>
<sec id="sec5">
<title>Personal Information Form</title>
<p>This form contains the socio-demographic characteristics of university graduates at 11universities of Shaanxi Province, including age, gender, major, and origin.</p>
<sec id="sec6">
<title>Perceived Stress Scale</title>
<p>The PSS was developed by Cohen et al., which is used to assess the degree of stress an individual feel in the past month (<xref ref-type="bibr" rid="ref9">Cohen et al., 1983</xref>). The Chinese version revised by Yang Tingzhong and Huang Hanteng was adopted (<xref ref-type="bibr" rid="ref43">Yang and Huang, 2003</xref>). The scores of the PSS with 14 items that used vary between 0 and 56. The participants were evaluated of each item on a 5-point Likert scale ranging from &#x201C;Never (0)&#x201D; to &#x201C;Very often (4).&#x201D; Seven of the items containing positive statements were scored in reverse order. The high score indicated the excessive perception of stress (<xref ref-type="bibr" rid="ref12">Eskin et al., 2013</xref>). The Alpha coefficient of the scale was found to be 0.86 (<xref ref-type="bibr" rid="ref43">Yang and Huang, 2003</xref>).</p>
</sec>
<sec id="sec7">
<title>State-Trait Anxiety Inventory</title>
<p>The State-Trait Anxiety Inventory is a test developed by Spielberger et al. that measures state and trait anxiety levels (<xref ref-type="bibr" rid="ref36">Spielberger et al., 1970</xref>). The scale consists of two parts, the &#x201C;state anxiety scale,&#x201D; which is created with the aim of determining the instantaneous feelings, and the &#x201C;trait anxiety scale,&#x201D; which is created to determine the feelings in general (<xref ref-type="bibr" rid="ref42">Yalcin et al., 2015</xref>; <xref ref-type="bibr" rid="ref24">Kuroshm et al., 2021</xref>). Each test consists of 20, 4-point Likert-type questions. It is a four-degree scale ranging from &#x201C;Nothing&#x201D; to &#x201C;All.&#x201D; Scores from each form vary between 20 and 80, with higher scores indicating greater anxiety. A total score of S-AI&#x003E;52 indicates state anxiety, and T-AI score&#x003E;53 is defined as trait anxiety. The Chinese version of the inventory was revised by Ye Renmin in 1990 (<xref ref-type="bibr" rid="ref38">Wang et al., 1999</xref>). It was stated that the State-Trait Anxiety Inventory (STAI) had an alpha value of 0.88 for reliability and 0.90 for validity (<xref ref-type="bibr" rid="ref38">Wang et al., 1999</xref>).</p>
</sec>
<sec id="sec8">
<title>Pittsburgh Sleep Quality Index</title>
<p>The PSQI is a questionnaire with 18 items assessing sleep quality over a 1-mo interval (<xref ref-type="bibr" rid="ref5">Buysse et al., 1989</xref>; <xref ref-type="bibr" rid="ref33">Okely et al., 2021</xref>). The scale was translated into Chinese by Liu Xianchen in 1996 (<xref ref-type="bibr" rid="ref30">Liu et al., 1996</xref>). The 18 items are grouped into seven dimensions: subjective sleep quality, sleep latency, sleep disturbances, sleep duration, habitual sleep efficiency, use of sleeping medication, and daytime dysfunction. The sum of scores for these seven dimensions yields a composite score, ranging from 0 to 21 (<xref ref-type="bibr" rid="ref41">Xiao et al., 2020</xref>; <xref ref-type="bibr" rid="ref21">Jacopo et al., 2021</xref>). Higher scores indicate worse sleep quality. A total score of PSQI&#x2265;8 indicates poor sleep quality, 5~7 indicates average sleep quality, and &#x2264;4 indicates good sleep quality. The factor score of PSQI&#x2265;2 indicates poor or very poor sleep quality on this factor. The reliability and validity of the scale were 0.99 and 0.85, respectively (<xref ref-type="bibr" rid="ref30">Liu et al., 1996</xref>).</p>
</sec>
</sec>
<sec id="sec9">
<title>Statistical Methods</title>
<p>In the data collection process, measurement tools were applied by applying an online data collection method. This work lasted 4months, using &#x201C;Personal Information Form,&#x201D; &#x201C;PSS,&#x201D; &#x201C;State-Trait Anxiety Inventory,&#x201D; and &#x201C;PSQI.&#x201D;</p>
<p>The data were analyzed using the SPSS version 23.0 software package. Percentages, Kruskal-Wallis, <italic>t</italic>-test, chi-square test, and correlations tests were used to evaluate the data. Kappa and correlation analyses were conducted to determine consistency among the observers. A value of <italic>p</italic>&#x003C;0.05 was considered statistically significant.</p>
</sec>
</sec>
<sec id="sec10" sec-type="results">
<title>Results</title>
<sec id="sec11">
<title>Descriptive Results</title>
<p>The socio-demographic characteristics of a total of 1,200 participants were showed in <xref rid="tab1" ref-type="table">Table 1</xref>. Among them, there were 628 males and 572 females. The average age was 23.36&#x00B1;2.72years, from 21 to 26. A total of 624 students (52%) majored in science and engineering, 445 students (37.08%) majored in liberal arts, and 131 students (10.92%) majored in medicine. A total of 52.42% of the participants came from urban families, while 47.58% of them were rural students.</p>
<table-wrap position="float" id="tab1">
<label>Table 1</label>
<caption>
<p>Socio-demographic characteristics of the study sample.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" colspan="2">Characteristics</th>
<th align="left" valign="top"><italic>n</italic>(%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="2">Gender</td>
<td align="left" valign="top">Male</td>
<td align="center" valign="top">628(52.33)</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="center" valign="top">572(47.67)</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">Major</td>
<td align="left" valign="top">Science and Engineering</td>
<td align="center" valign="top">624(52.0)</td>
</tr>
<tr>
<td align="left" valign="top">Liberal Arts</td>
<td align="center" valign="top">445(37.08)</td>
</tr>
<tr>
<td align="left" valign="top">Medicine</td>
<td align="center" valign="top">131(10.92)</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">Origin</td>
<td align="left" valign="top">Urban</td>
<td align="center" valign="top">629(52.42)</td>
</tr>
<tr>
<td align="left" valign="top">Rural</td>
<td align="center" valign="top">571(47.58)</td>
</tr>
<tr>
<td align="left" valign="top" colspan="2">Age(Mean&#x00B1;SD)</td>
<td align="center" valign="top">23.36&#x00B1;2.72</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The mean scores of the sample on the PSS, STAI, and PSQI were showed in <xref rid="tab2" ref-type="table">Table 2</xref>. The mean perceived stress, state anxiety, trait anxiety, and sleep quality were moderate and found as 31.4&#x00B1;6.69, 46.67&#x00B1;5.80, 49.45&#x00B1;5.54, and 5.94&#x00B1;2.47, respectively.</p>
<table-wrap position="float" id="tab2">
<label>Table 2</label>
<caption>
<p>Mean scores of the sample on the PSS, STAI, and PSQI.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top"/>
<th align="center" valign="top">M + N-MAX</th>
<th align="center" valign="top">Mean(SD)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Perceived Stress Scale</td>
<td align="center" valign="top">0~56</td>
<td align="center" valign="top">31.44 &#x00B1; 6.69</td>
</tr>
<tr>
<td align="left" valign="top">State Anxiety</td>
<td align="center" valign="top">20~80</td>
<td align="center" valign="top">46.67 &#x00B1; 7.80</td>
</tr>
<tr>
<td align="left" valign="top">Trait Anxiety</td>
<td align="center" valign="top">20~80</td>
<td align="center" valign="top">49.25 &#x00B1; 7.54</td>
</tr>
<tr>
<td align="left" valign="top">Sleep Quality Scale</td>
<td align="center" valign="top">0~21</td>
<td align="center" valign="top">5.94 &#x00B1; 2.47</td>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec12">
<title>Correlations Between Outcomes</title>
<p>The average scores of state anxiety and trait anxiety were 46.67&#x00B1;7.80 and 49.25&#x00B1;7.54, respectively. The detection rates of state anxiety and trait anxiety among 1,200 university graduates were 48.42 and 49.25%, respectively. As shown in <xref rid="tab3" ref-type="table">Table 3</xref>, there was no significant difference in the detection rates of state anxiety and trait anxiety among university graduates of different genders and majors (<italic>p</italic>&#x2265;0.05). The detection rates of state anxiety and trait anxiety in rural students were higher than those in urban areas, and the differences were statistically significant (<italic>p</italic>&#x003C;0.01).</p>
<table-wrap position="float" id="tab3">
<label>Table 3</label>
<caption>
<p>The comparison of socio-demographic characteristics between the detection rate of state anxiety and trait anxiety.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" colspan="2">Characteristics</th>
<th align="left" valign="top">n</th>
<th align="center" valign="top">Test, <italic>p</italic> value</th>
<th align="center" valign="top">State Anxiety (Detection rate/%)</th>
<th align="center" valign="top">Trait Anxiety (Detection rate/%)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="4">Gender</td>
<td align="left" valign="top">Male</td>
<td align="center" valign="top">628</td>
<td align="center" valign="top"/>
<td align="center" valign="top">294(46.82%)</td>
<td align="center" valign="top">299(47.61%)</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="center" valign="top">572</td>
<td align="center" valign="top"/>
<td align="center" valign="top">287(50.17%)</td>
<td align="center" valign="top">292(51.05%)</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top"><italic>&#x03C7;</italic><sup>2</sup></td>
<td align="center" valign="top">0.89</td>
<td align="center" valign="top">1.00</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top">p</td>
<td align="center" valign="top">&#x003E;0.05</td>
<td align="center" valign="top">&#x003E;0.05</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="5">Major</td>
<td align="left" valign="top">Science and Engineering</td>
<td align="center" valign="top">624</td>
<td align="center" valign="top"/>
<td align="center" valign="top">297(47.60%)</td>
<td align="center" valign="top">303(48.56%)</td>
</tr>
<tr>
<td align="left" valign="top">Liberal arts</td>
<td align="left" valign="top">445</td>
<td align="center" valign="top"/>
<td align="center" valign="top">219(49.21%)</td>
<td align="center" valign="top">226(50.79%)</td>
</tr>
<tr>
<td align="left" valign="top">Medicine</td>
<td align="center" valign="top">131</td>
<td align="center" valign="top"/>
<td align="center" valign="top">65(49.62%)</td>
<td align="center" valign="top">62(47.33%)</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top"><italic>&#x03C7;</italic><sup>2</sup></td>
<td align="center" valign="top">0.18</td>
<td align="center" valign="top">0.07</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top">p</td>
<td align="center" valign="top">&#x003E;0.05</td>
<td align="center" valign="top">&#x003E;0.05</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="4">Origin</td>
<td align="left" valign="top">Urban</td>
<td align="center" valign="top">629</td>
<td align="center" valign="top"/>
<td align="center" valign="top">243(38.63%)</td>
<td align="center" valign="top">252(40.06%)</td>
</tr>
<tr>
<td align="left" valign="top">Rural</td>
<td align="center" valign="top">571</td>
<td align="center" valign="top"/>
<td align="center" valign="top">338(59.19%)</td>
<td align="center" valign="top">339(59.37)</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top"><italic>&#x03C7;</italic><sup>2</sup></td>
<td align="center" valign="top">31.39</td>
<td align="center" valign="top">22.29</td>
</tr>
<tr>
<td align="center" valign="top"/>
<td align="center" valign="top"/>
<td align="center" valign="top">p</td>
<td align="center" valign="top">&#x003C;0.01</td>
<td align="center" valign="top">&#x003C;0.01</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The total average score of PSQI was 5.94&#x00B1;2.47. As shown in <xref rid="tab4" ref-type="table">Table 4</xref>, according to the evaluation standard, among 1,200 university graduates, 27.83% had poor sleep quality, 54.83% had average sleep quality, and 17.33% had good sleep quality. The main symptoms of poor sleep were 77.92% daytime dysfunction, 47.08% sleep duration, 27.33% subjective sleep quality, and 24.25% sleep latency. There were significant differences in the distribution of sleep quality among university graduates from different majors and origins (<italic>p</italic>&#x003C;0.01).</p>
<table-wrap position="float" id="tab4">
<label>Table 4</label>
<caption>
<p>The comparison of socio-demographic characteristics in the distribution of sleep quality.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" colspan="2">Characteristics</th>
<th align="center" valign="top"><italic>n</italic></th>
<th align="center" valign="top">Poor sleep quality (Constituent Ratio/%)</th>
<th align="center" valign="top">Average sleep quality (Constituent Ratio/%)</th>
<th align="center" valign="top">Good sleep quality (Constituent Ratio/%)</th>
<th align="center" valign="top"><italic>&#x03C7;</italic><sup>2</sup></th>
<th align="center" valign="top"><italic>p</italic></th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="2">Gender</td>
<td align="left" valign="middle">Male</td>
<td align="center" valign="middle">628</td>
<td align="center" valign="top">173(27.55)</td>
<td align="center" valign="top">344(54.78)</td>
<td align="center" valign="top">111(17.68)</td>
<td align="center" valign="top" rowspan="2">3.04</td>
<td align="center" valign="top" rowspan="2">&#x003E;0.05</td>
</tr>
<tr>
<td align="left" valign="top">Female</td>
<td align="center" valign="middle">572</td>
<td align="center" valign="top">161(28.15)</td>
<td align="center" valign="top">314(54.90)</td>
<td align="center" valign="top">97(16.96)</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">Major</td>
<td align="left" valign="middle">Science and Engineering</td>
<td align="center" valign="middle">624</td>
<td align="center" valign="top">158(25.32)</td>
<td align="center" valign="top">359(57.53)</td>
<td align="center" valign="top">107(17.15)</td>
<td align="center" valign="top" rowspan="3">13.54</td>
<td align="center" valign="top" rowspan="3">&#x003C;0.01</td>
</tr>
<tr>
<td align="left" valign="middle">Liberal arts</td>
<td align="center" valign="middle">445</td>
<td align="center" valign="top">139(31.24)</td>
<td align="center" valign="top">230(51.69)</td>
<td align="center" valign="top">76(17.08)</td>
</tr>
<tr>
<td align="left" valign="middle">Medicine</td>
<td align="center" valign="middle">131</td>
<td align="center" valign="top">37(28.24)</td>
<td align="center" valign="top">69(52.67)</td>
<td align="center" valign="top">25(19.08)</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">Origin</td>
<td align="left" valign="middle">Urban</td>
<td align="center" valign="middle">629</td>
<td align="center" valign="top">153(24.32)</td>
<td align="center" valign="top">328(52.15)</td>
<td align="center" valign="top">148(23.53)</td>
<td align="center" valign="top" rowspan="2">16.33</td>
<td align="center" valign="top" rowspan="2">&#x003C;0.01</td>
</tr>
<tr>
<td align="left" valign="middle">Rural</td>
<td align="center" valign="middle">571</td>
<td align="center" valign="top">181(31.70)</td>
<td align="center" valign="top">330(57.79)</td>
<td align="center" valign="top">60(10.51)</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The relationships between the socio-demographic characteristics and mean scores of the sample on the PSS, STAI, and PSQI were showed in <xref rid="tab5" ref-type="table">Table 5</xref>. According to the results, there was no statistically significant correlation between perceived stress scores and socio-demographic characteristics. State anxiety levels were significantly higher in woman students than man students (<italic>p</italic>&#x003C;0.05). University graduates who came from rural families had significantly higher state anxiety levels (<italic>p</italic>&#x003C;0.05). There were no significant differences found in terms of trait anxiety levels.</p>
<table-wrap position="float" id="tab5">
<label>Table 5</label>
<caption>
<p>The comparison of socio-demographic characteristics between mean scores of the sample on the PSS, STAI, and PSQI.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" colspan="2">Characteristics</th>
<th align="center" valign="top">PSS score(M&#x00B1;SD)</th>
<th align="center" valign="top">S-AI score(M&#x00B1;SD)</th>
<th align="center" valign="top">T-AI score(M&#x00B1;SD)</th>
<th align="center" valign="top">PSQI score(M&#x00B1;SD)</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="4">Gender</td>
<td align="left" valign="middle">Male</td>
<td align="center" valign="top">30.88&#x00B1;6.47</td>
<td align="center" valign="top">45.49&#x00B1;7.04</td>
<td align="center" valign="top">48.59&#x00B1;8.12</td>
<td align="center" valign="top">5.82&#x00B1;2.51</td>
</tr>
<tr>
<td align="left" valign="middle">Female</td>
<td align="center" valign="top">32.05&#x00B1;6.93</td>
<td align="center" valign="top">47.96&#x00B1;8.63</td>
<td align="center" valign="top">49.98&#x00B1;6.91</td>
<td align="center" valign="top">6.07&#x00B1;2.43</td>
</tr>
<tr>
<td align="left" valign="middle" rowspan="2">Test, p value</td>
<td align="center" valign="top"><italic>t</italic> =&#x2212;1.324</td>
<td align="center" valign="top"><italic>t</italic> =2.803</td>
<td align="center" valign="top"><italic>t</italic> =&#x2212;1.951</td>
<td align="center" valign="top"><italic>t</italic> =1.477</td>
</tr>
<tr>
<td align="center" valign="top"><italic>p</italic> =0.184</td>
<td align="center" valign="top"><italic>p</italic> =0.005</td>
<td align="center" valign="top"><italic>p</italic> =0.053</td>
<td align="center" valign="top"><italic>p</italic> =0.141</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="4">Major</td>
<td align="left" valign="middle">Science and Engineering</td>
<td align="center" valign="top">30.87&#x00B1;6.31</td>
<td align="center" valign="top">46.94&#x00B1;9.09</td>
<td align="center" valign="top">49.81&#x00B1;8.24</td>
<td align="center" valign="top">5.82&#x00B1;2.41</td>
</tr>
<tr>
<td align="left" valign="middle">Liberal arts</td>
<td align="center" valign="top">32.24&#x00B1;5.98</td>
<td align="center" valign="top">46.63&#x00B1;8.52</td>
<td align="center" valign="top">48.86&#x00B1;6.79</td>
<td align="center" valign="top">6.11&#x00B1;2.49</td>
</tr>
<tr>
<td align="left" valign="middle">Medicine</td>
<td align="center" valign="top">31.41&#x00B1;7.33</td>
<td align="center" valign="top">45.67&#x00B1;6.92</td>
<td align="center" valign="top">47.92&#x00B1;6.75</td>
<td align="center" valign="top">5.93&#x00B1;2.68</td>
</tr>
<tr>
<td align="left" valign="middle">Test, p value</td>
<td align="center" valign="top">KW=4.077 <italic>p</italic> =0.231</td>
<td align="center" valign="top">KW=1.124 <italic>p</italic> =0.737</td>
<td align="center" valign="top">KW=0.902 <italic>p</italic> =0.813</td>
<td align="center" valign="top">KW=0.902 <italic>p</italic> =0.813</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="3">Origin</td>
<td align="left" valign="middle">Urban</td>
<td align="center" valign="top">30.82&#x00B1;7.09</td>
<td align="center" valign="top">45.73&#x00B1;7.34</td>
<td align="center" valign="top">49.13&#x00B1;7.03</td>
<td align="center" valign="top">5.69&#x00B1;2.62</td>
</tr>
<tr>
<td align="left" valign="middle">Rural</td>
<td align="center" valign="top">31.94&#x00B1;6.24</td>
<td align="center" valign="top">47.68&#x00B1;8.27</td>
<td align="center" valign="top">49.36&#x00B1;8.12</td>
<td align="center" valign="top">6.23&#x00B1;2.31</td>
</tr>
<tr>
<td align="left" valign="middle">Test, p value</td>
<td align="center" valign="top"><italic>t</italic> =0.356 <italic>p</italic> =0.722</td>
<td align="center" valign="top"><italic>t</italic> =1.967 <italic>p</italic> =0.050</td>
<td align="center" valign="top"><italic>t</italic> =0.136 <italic>p</italic> =0.892</td>
<td align="center" valign="top"><italic>t</italic> =1.113 <italic>p</italic> =0.127</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>According to the correlation analysis in <xref rid="tab6" ref-type="table">Table 6</xref>, there was no significant relationship between state anxiety and perceived stress (<italic>r</italic>=&#x2212;0.037, <italic>p</italic>=0.611). There was also no significant relationship between sleep quality and perceived stress (<italic>r</italic>=&#x2212;0.037, <italic>p</italic>=0.611). However, a positive relationship was found between the trait anxiety and perceived stress (<italic>r</italic>=0.164, <italic>p</italic>=0.016), state anxiety and trait anxiety (<italic>r</italic> =0.520, <italic>p</italic>=0.000), state anxiety and sleep quality (<italic>r</italic>=0.157, <italic>p</italic>=0.021), and trait anxiety and sleep quality (<italic>r</italic>=0.142, <italic>p</italic>=0.041).</p>
<table-wrap position="float" id="tab6">
<label>Table 6</label>
<caption>
<p>Correlations between the PSS, the STAI, and the PSQI.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top" colspan="2">Characteristics</th>
<th align="center" valign="top">PSS</th>
<th align="center" valign="top">S-AI</th>
<th align="center" valign="top">T-AI</th>
<th align="center" valign="top">PSQI</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top" rowspan="2">PSS</td>
<td align="center" valign="top">r</td>
<td align="center" valign="top"/>
<td align="center" valign="top">&#x2212;0.037</td>
<td align="center" valign="top">0.164</td>
<td align="center" valign="top">&#x2212;0.037</td>
</tr>
<tr>
<td align="center" valign="top">P</td>
<td align="center" valign="top"/>
<td align="center" valign="top">0.611</td>
<td align="center" valign="top">0.016</td>
<td align="center" valign="top">0.607</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">S-AI</td>
<td align="center" valign="top">r</td>
<td align="center" valign="top">&#x2212;0.037</td>
<td align="center" valign="top"/>
<td align="center" valign="top">0.520</td>
<td align="center" valign="top">0.157</td>
</tr>
<tr>
<td align="center" valign="top">P</td>
<td align="center" valign="top">0.611</td>
<td align="center" valign="top"/>
<td align="center" valign="top">0.000</td>
<td align="center" valign="top">0.021</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">T-AI</td>
<td align="center" valign="top">r</td>
<td align="center" valign="top">0.164</td>
<td align="center" valign="top">0.520</td>
<td align="center" valign="top"/>
<td align="center" valign="top">0.142</td>
</tr>
<tr>
<td align="center" valign="top">P</td>
<td align="center" valign="top">0.016</td>
<td align="center" valign="top">0.000</td>
<td align="center" valign="top"/>
<td align="center" valign="top">0.041</td>
</tr>
<tr>
<td align="left" valign="top" rowspan="2">PSQI</td>
<td align="center" valign="top">r</td>
<td align="center" valign="top">&#x2212;0.037</td>
<td align="center" valign="top">0.157</td>
<td align="center" valign="top">0.142</td>
<td align="center" valign="top"/>
</tr>
<tr>
<td align="center" valign="top">P</td>
<td align="center" valign="top">0.607</td>
<td align="center" valign="top">0.021</td>
<td align="center" valign="top">0.041</td>
<td align="center" valign="top"/>
</tr>
</tbody>
</table>
</table-wrap>
</sec>
<sec id="sec13">
<title>Predictors of Change</title>
<p>Taking state anxiety and trait anxiety as dependent variables, sleep quality score as independent variables, and gender, major category, and origin as control variables, binary logistic regression analysis was conducted. The results in <xref rid="tab7" ref-type="table">Table 7</xref> showed that the evaluation results and total scores of sleep quality of university graduates were positively correlated with state anxiety and trait anxiety.</p>
<table-wrap position="float" id="tab7">
<label>Table 7</label>
<caption>
<p>Regression analysis on the relationship between sleep quality and state-trait anxiety [n=1,200 odd ratio (OR, 95%CI)].</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th align="left" valign="top">Sleep quality</th>
<th align="center" valign="top">State anxiety</th>
<th align="center" valign="top">Trait anxiety</th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Subjective sleep quality</td>
<td align="center" valign="top">2.02 (1.73~2.94)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
<td align="center" valign="top">2.07 (1.49~2.16)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Sleep duration</td>
<td align="center" valign="top">1.81 (1.71~1.99)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
<td align="center" valign="top">1.98 (1.68~3.92)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Sleep latency</td>
<td align="center" valign="top">2.84 (1.65~3.12)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
<td align="center" valign="top">3.08 (1.47~3.91)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Daytime dysfunction</td>
<td align="center" valign="top">3.24 (1.86~3.68)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
<td align="center" valign="top">3.37 (2.67~4.81)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Habitual sleep efficiency</td>
<td align="center" valign="top">2.07 (1.65~2.57)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
<td align="center" valign="top">2.21 (1.68~3.95)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Use of sleeping medication</td>
<td align="center" valign="top">3.20 (1.98~4.34)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
<td align="center" valign="top">3.64 (1.92~3.80)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Sleep disturbances</td>
<td align="center" valign="top">2.98 (1.33~3.09)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
<td align="center" valign="top">3.11 (1.72~4.00)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Total score</td>
<td align="center" valign="top">2.57 (1.86~2.97)<xref rid="tfn2" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
<td align="center" valign="top">3.04(2.04~3.71)<xref rid="tfn1" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="tfn1">
<label>&#x002A;</label>
<p><italic>p&#x003C;0.05</italic></p>
</fn>
<p><italic>and</italic></p>
<fn id="tfn2">
<label>&#x002A;&#x002A;</label>
<p><italic>p&#x003C;0.01</italic>.</p>
</fn>
</table-wrap-foot>
</table-wrap>
<p>Taking trait anxiety as the independent variable and the total score of PSQI and its factors (subjective sleep quality and sleep duration) as the dependent variable, the regression equations were constructed. The results were showed in <xref rid="tab8" ref-type="table">Table 8</xref>. Trait anxiety had a significant predictive effect on subjective sleep quality, sleep duration, and PSQI total score, and the explained amount of variation was 2.56, 2.69, and 1.84%, respectively.</p>
<table-wrap position="float" id="tab8">
<label>Table 8</label>
<caption>
<p>Regression analysis of trait anxiety and sleep quality.</p>
</caption>
<table frame="hsides" rules="groups">
<thead>
<tr>
<th/>
<th align="left" valign="top">&#x0394;<italic>R</italic><sup>2</sup></th>
<th align="left" valign="top"><italic>F</italic></th>
<th align="left" valign="top"><italic>&#x03B2;</italic></th>
<th align="left" valign="top"><italic>t</italic></th>
</tr>
</thead>
<tbody>
<tr>
<td align="left" valign="top">Subjective sleep quality</td>
<td align="center" valign="top">0.03</td>
<td align="center" valign="top">12.37</td>
<td align="center" valign="top">0.16</td>
<td align="center" valign="top">3.51<xref rid="tfn4" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">Sleep duration</td>
<td align="center" valign="top">0.01</td>
<td align="center" valign="top">5.44</td>
<td align="center" valign="top">0.11</td>
<td align="center" valign="top">2.33<xref rid="tfn3" ref-type="table-fn"><sup>&#x002A;</sup></xref></td>
</tr>
<tr>
<td align="left" valign="top">PSQI total score</td>
<td align="center" valign="top">0.02</td>
<td align="center" valign="top">11.58</td>
<td align="center" valign="top">0.16</td>
<td align="center" valign="top">3.39<xref rid="tfn4" ref-type="table-fn"><sup>&#x002A;&#x002A;</sup></xref></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<fn id="tfn3">
<label>&#x002A;</label>
<p><italic>p&#x003C;0.05</italic></p>
</fn>
<p><italic>and</italic></p>
<fn id="tfn4">
<label>&#x002A;&#x002A;</label>
<p><italic>p&#x003C;0.01</italic>.</p>
</fn>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec id="sec14" sec-type="discussions">
<title>Discussion</title>
<p>In the fight against the COVID-19 pandemic, it is extremely important to identify the factors that affect the psychological health of university graduates. A general picture of the psychological state of university graduates in China during the COVID-19 pandemic has been presented. Pandemics have many negative effects on society, economy, psychology, and spirit (<xref ref-type="bibr" rid="ref14">Fong et al., 2020</xref>; <xref ref-type="bibr" rid="ref17">Gao et al., 2020</xref>; <xref ref-type="bibr" rid="ref35">Salari et al., 2020</xref>; <xref ref-type="bibr" rid="ref39">Wang et al., 2020</xref>; <xref ref-type="bibr" rid="ref46">Zhang and Ma, 2020</xref>; <xref ref-type="bibr" rid="ref26">Li et al., 2020c</xref>). Under the pressure of study and employment, the mental health of university graduates has always been the focus of colleges and society (<xref ref-type="bibr" rid="ref22">Kahn, 2010</xref>; <xref ref-type="bibr" rid="ref1">Altonji et al., 2016</xref>). Therefore, the impact of novel coronavirus pneumonia, the fear of leaving campus, fierce competition, huge employment pressure, and worries about future development can cause serious mental health problems for university graduates. Lack of sleep or poor sleep quality can lead to college students&#x2019; fatigue, inattentiveness, low learning efficiency, and other undesirable phenomena (<xref ref-type="bibr" rid="ref15">Gadie et al., 2017</xref>; <xref ref-type="bibr" rid="ref3">Barros et al., 2019</xref>; <xref ref-type="bibr" rid="ref6">Cao et al., 2021</xref>).</p>
<p>Through this cross-sectional study, the mental health problems and the associated factors among Chinese university graduates with pressure increases exposed to COVID-19 were assessed. The degrees of the perceived stress, anxiety, and sleep quality of 1,200 participants were assessed using the Perceived Stress Scale, the State-Trait Anxiety Inventory, and the PSQI, respectively, which found that the mean perceived stress, state anxiety, trait anxiety, and sleep quality were moderate and found as 31.4&#x00B1;6.69, 46.67&#x00B1;5.80, 49.45&#x00B1;5.54, and5.94&#x00B1;2.47, respectively.</p>
<p>The findings of this study demonstrated that the perceived stress, anxiety, and sleep quality of university graduates were affected by some demographic variables. The results showed that the detection rates of state anxiety and trait anxiety were 48.63 and 49.50%. A considerable number of university graduates had different degrees of state anxiety and trait anxiety, which was significantly higher than the detection rates of state anxiety and trait anxiety on the adult population in other studies (<xref ref-type="bibr" rid="ref31">Madrid-Valero et al., 2017</xref>). The reason for this analysis is that the university graduates will face more pressure, unclear future planning, and fierce competition for employment under the influence of COVID-19. This shows that during the period of COVID-19, universities and all sectors of society should give university graduates more care and psychological support to help them to clear up negative emotions and avoid serious harm to their mental health.</p>
<p>In addition, the detection rates of state anxiety and trait anxiety of different genders and different majors were similar, which indicated that there was a high risk of anxiety for both males and females, regardless of their majors. This study found that state anxiety levels were significantly higher in females than males (<italic>p</italic>&#x003C;0.05). This was consistent with the greater pressure on female employment in the current society. The detection rates of state anxiety and trait anxiety on rural students were higher than those in urban areas. It was speculated that it may be due to the low financial support of rural families for further study and the great economic pressure of employment for their families. Serving as reserve talents for the healthcare system, medical students were not yet professionally matured enough to face one of the worst global public health crises. The perceived stress and anxiety induced by the COVID-19 epidemic might affect medical students&#x2019; future career choice (<xref ref-type="bibr" rid="ref48">Zheng et al., 2021</xref>).</p>
<p>There was a close relationship between state-trait anxiety and sleep quality of university graduates. Multivariable logistic regression analysis was performed to identify factors associated with mental health outcomes among university graduates during COVID-19. The regression analysis showed that each factor and total score of sleep quality were positively correlated with state and trait anxiety. They can influence each other and form a vicious circle (<xref ref-type="bibr" rid="ref29">Liu et al., 2016</xref>). The relationship between sleep quality and anxiety should be paid attention in order to reduce the state and trait anxiety of university graduates. The results of the study showed that trait anxiety had a significant predictive effect on subjective sleep quality, sleep duration, and PSQI total score.</p>
</sec>
<sec id="sec15" sec-type="conclusions">
<title>Conclusion</title>
<p>The study managed to capture some immediate positive and negative mental health impacts of the COVID-19 pandemic. The results showed that rural graduates looking for employment, especially students majored in liberal arts, were found to have a high risk of mental health symptoms that were not conducive to development and may need psychological support or interventions. Since the COVID-19 pandemic is still ongoing, these findings need to be confirmed and investigated in future.</p>
</sec>
<sec id="sec16">
<title>Limitations</title>
<p>This study is a cross-sectional study, which can not reveal the causal direction of the relationship between perceived stress, state-trait anxiety, and sleep quality. It needs to carry out a prospective cohort study to explore.</p>
<p>The effect of state anxiety on sleep quality is direct and significant. The trait anxiety can trigger and cause all kinds of sleep problems by influencing individual anxiety tendency steadily. In this study, the explanation rate of trait anxiety to the variance of PSQI is not high, which may also be due to this. Trait anxiety has an indirect effect on sleep quality, which mainly affects sleep quality through the mediating effect of state anxiety.</p>
</sec>
<sec id="sec17" sec-type="data-availability">
<title>Data Availability Statement</title>
<p>The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.</p>
</sec>
<sec id="sec18">
<title>Ethics Statement</title>
<p>The studies involving human participants were reviewed and approved by the Ethics Committee of Xi&#x2019;an University of Architecture and Technology. The patients/participants provided their written informed consent to participate in this study.</p>
</sec>
<sec id="sec19">
<title>Author Contributions</title>
<p>BL conceived the initial idea for the study and helped to study design. KQ designed the study, collected the data, performed the statistical analysis, and helped to recruit the participants. BL and YL contributed to intervention design and draft the manuscript. All authors have read and agreed to the published version of the manuscript.</p>
</sec>
<sec id="sec41" sec-type="funding-information">
<title>Funding</title>
<p>This study is supported by the Excellent Project of University Student Work in Shaanxi Province (2020FXM06).</p>
</sec>
<sec id="conf1" sec-type="COI-statement">
<title>Conflict of Interest</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
<sec id="sec001" sec-type="disclaimer">
<title>Publisher&#x2019;s Note</title>
<p>All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.</p>
</sec>
</body>
<back>
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