AUTHOR=Narita Zui , Inagawa Takuma , Sueyoshi Kazuki , Lin Crystal , Sumiyoshi Tomiki TITLE=Possible Facilitative Effects of Repeated Anodal Transcranial Direct Current Stimulation on Functional Outcome 1 Month Later in Schizophrenia: An Open Trial JOURNAL=Frontiers in Psychiatry VOLUME=8 YEAR=2017 URL=https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2017.00184 DOI=10.3389/fpsyt.2017.00184 ISSN=1664-0640 ABSTRACT=
Recent research on neuromodulation techniques, such as transcranial direct current stimulation (tDCS), for the treatment of schizophrenia has mainly focused on psychotic symptoms. We aimed to determine whether repetitive tDCS is efficacious in improving determinants of outcome, such as cognitive function, daily living skills, and depressive mood in patients with schizophrenia. Twenty-eight patients underwent tDCS (2 mA × 20 min) two times per day for 5 consecutive days. The anodal electrode was placed over the left dorsolateral prefrontal cortex while the cathodal electrode was placed over the right supraorbital region. One month after the last stimulation, there was a significant improvement on cognitive function, measured by the brief assessment of cognition in schizophrenia (