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<front>
<journal-meta>
<journal-id journal-id-type="publisher-id">Front. Psychiatry</journal-id>
<journal-title>Frontiers in Psychiatry</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Front. Psychiatry</abbrev-journal-title>
<issn pub-type="epub">1664-0640</issn>
<publisher>
<publisher-name>Frontiers Media S.A.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="doi">10.3389/fpsyt.2019.00139</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Psychiatry</subject>
<subj-group>
<subject>Original Research</subject>
</subj-group>
</subj-group>
</article-categories>
<title-group>
<article-title>The Psychometric Properties of a Short UPPS-P Impulsive Behavior Scale Among Psychiatric Patients Evaluated in an Emergency Setting</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name><surname>Dugr&#x000E9;</surname> <given-names>Jules Roger</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/406415/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Gigu&#x000E9;re</surname> <given-names>Charles-&#x000C9;douard</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/659793/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Percie du Sert</surname> <given-names>Olivier</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/694561/overview"/>
</contrib>
<contrib contrib-type="author">
<name><surname>Potvin</surname> <given-names>Stephane</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/27411/overview"/>
</contrib>
<contrib contrib-type="author" corresp="yes">
<name><surname>Dumais</surname> <given-names>Alexandre</given-names></name>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
<xref ref-type="aff" rid="aff2"><sup>2</sup></xref>
<xref ref-type="aff" rid="aff3"><sup>3</sup></xref>
<xref ref-type="corresp" rid="c001"><sup>&#x0002A;</sup></xref>
<uri xlink:href="http://loop.frontiersin.org/people/435947/overview"/>
</contrib>
<contrib contrib-type="author">
<collab>Consortium Signature</collab>
<xref ref-type="aff" rid="aff1"><sup>1</sup></xref>
</contrib>
</contrib-group>
<aff id="aff1"><sup>1</sup><institution>Department of Psychiatry, Institut Universitaire en Sant&#x000E9; Mentale de Montr&#x000E9;al</institution>, <addr-line>Montreal, QC</addr-line>, <country>Canada</country></aff>
<aff id="aff2"><sup>2</sup><institution>D&#x000E9;partement de Psychiatrie et d&#x00027;addictologie, Facult&#x000E9; de M&#x000E9;decine, Universit&#x000E9; de Montr&#x000E9;al</institution>, <addr-line>Montreal, QC</addr-line>, <country>Canada</country></aff>
<aff id="aff3"><sup>3</sup><institution>Department of Psychiatry, Institut National de Psychiatrie l&#x000E9;gale Philippe-Pinel</institution>, <addr-line>Montreal, QC</addr-line>, <country>Canada</country></aff>
<author-notes>
<fn fn-type="edited-by"><p>Edited by: Roumen Kirov, Institute of Neurobiology (BAS), Bulgaria</p></fn>
<fn fn-type="edited-by"><p>Reviewed by: Serge Brand, University Psychiatric Clinic Basel, Switzerland; Marvin D. Krank, University of British Columbia, Canada</p></fn>
<corresp id="c001">&#x0002A;Correspondence: Alexandre Dumais <email>alexandre.dumais&#x00040;umontreal.ca</email></corresp>
<fn fn-type="other" id="fn001"><p>This article was submitted to Psychopathology, a section of the journal Frontiers in Psychiatry</p></fn></author-notes>
<pub-date pub-type="epub">
<day>25</day>
<month>03</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="collection">
<year>2019</year>
</pub-date>
<volume>10</volume>
<elocation-id>139</elocation-id>
<history>
<date date-type="received">
<day>19</day>
<month>08</month>
<year>2018</year>
</date>
<date date-type="accepted">
<day>26</day>
<month>02</month>
<year>2019</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright &#x000A9; 2019 Dugr&#x000E9;, Gigu&#x000E9;re, Percie du Sert, Potvin, Dumais and Consortium Signature.</copyright-statement>
<copyright-year>2019</copyright-year>
<copyright-holder>Dugr&#x000E9;, Gigu&#x000E9;re, Percie du Sert, Potvin, Dumais and Consortium Signature</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.</p></license>
</permissions>
<abstract><p><bold>Objective:</bold> Impulsivity is a multidimensional construct that has an important role for the understanding of diverse psychopathologies and problematic behaviors. The UPPS-P impulsive behavior scale, measuring five distinct facets of impulsivity, has been subject to several studies. No study has investigated the clinical utility of this questionnaire amongst an unstable psychiatric population. The aim of the current study is to examine the psychometric properties of the short version of this scale in a psychiatric emergency unit.</p>
<p><bold>Method:</bold> The S-UPPS-P was administered to 1,097 psychiatric patients in an emergency setting, where a subgroup of 148 participants completed a follow-up. The internal consistency, the construct validity, the test-retest reliability, and correlations with a substance misuse measure were examined.</p>
<p><bold>Results:</bold> Confirmatory factor analyses supported a five-factor solution. Results indicated good psychometric properties across psychiatric diagnoses and gender. The S-UPPS-P was partially invariant across sexes. The authors have found differences on the loading of one item and on the thresholds of two items from lack of premeditation and positive urgency subscales.</p>
<p><bold>Conclusion:</bold> This validation study showed that the UPPS-P conserved good psychometric properties in an unstable psychiatric sample, indicating that the instrument can be utilized in such settings.</p></abstract>
<kwd-group>
<kwd>impulsivity</kwd>
<kwd>short version</kwd>
<kwd>reliability</kwd>
<kwd>validity</kwd>
<kwd>psychiatric emergency</kwd>
</kwd-group>
<counts>
<fig-count count="3"/>
<table-count count="5"/>
<equation-count count="0"/>
<ref-count count="44"/>
<page-count count="9"/>
<word-count count="5792"/>
</counts>
</article-meta>
</front>
<body>
<sec sec-type="intro" id="s1">
<title>Introduction</title>
<p>The nature of impulsivity, now known to be heterogeneous (<xref ref-type="bibr" rid="B1">1</xref>), is generally characterized by deficits in delaying gratification, impulse and urge control, decision making, and maladaptive behaviors (<xref ref-type="bibr" rid="B2">2</xref>). Its cross-cutting nosology component, in line with the Research Domain Criteria framework (e.g., RDoC Cognitive Systems) (<xref ref-type="bibr" rid="B3">3</xref>, <xref ref-type="bibr" rid="B4">4</xref>), plays a major role in the understanding of diverse psychopathologies and problematic behaviors. In fact, it is not surprising that impulsivity is one of the most common diagnostic criteria in the fifth edition of the <italic>Diagnostic and Statistical Manual for Mental Disorders</italic> (<xref ref-type="bibr" rid="B5">5</xref>) (e.g., Attention Deficit Hyperactivity Disorder and Conduct Disorder, Borderline Personality Disorder, Antisocial Personality Disorder, Substance Use Disorders, Bipolar Disorder).</p>
<p>However, it is interesting to note that impulsivity has been subject to terminological and conceptual confusion. To clarify the jingle-jangle fallacy<xref ref-type="fn" rid="fn0001"><sup>1</sup></xref> of impulsivity (<xref ref-type="bibr" rid="B6">6</xref>), exploratory and confirmatory factor analyses have been performed using the Urgency-Premeditation-Perseverance-Sensation Seeking-Positive Urgency (UPPS-P) impulsive behavior scale which revealed five specific facets of impulsivity (<xref ref-type="bibr" rid="B7">7</xref>). These dimensions are <italic>sensation seeking</italic> (tendency to seek out novel and thrilling experiences), <italic>lack of premedita</italic>tion (tendency to not take into account the consequences of actions), <italic>lack of perseverance</italic> (tendency to have difficulty staying focused on a task that can be long, boring or difficult), <italic>negative urgency</italic> (the tendency to act rashly while in an intense negative mood), and <italic>positive urgency</italic> (the tendency to act rashly while in an intense positive mood).</p>
<p>Several studies have observed associations between the different dimensions of UPPS-P and distinct psychopathologies and problematic behaviors (e.g., substance abuse/dependence, aggressive and suicidal behaviors). In fact, <italic>Lack of Premeditation</italic> has been shown to be associated with substance misuse (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B9">9</xref>), antisocial (ASPD) and borderline personality disorder (BPD) features (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B11">11</xref>), and violent behaviors (<xref ref-type="bibr" rid="B12">12</xref>, <xref ref-type="bibr" rid="B13">13</xref>). <italic>Lack of Perseverance</italic> has been related to problematic substance use (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B14">14</xref>), BPD characteristics (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B10">10</xref>), and aggression (<xref ref-type="bibr" rid="B15">15</xref>). In regard to <italic>Sensation Seeking</italic>, studies have demonstrated a link with drug and alcohol use, gambling, ASPD traits, and delinquency (<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B17">17</xref>). <italic>Positive Urgency</italic> has been associated with illegal drug use and risky sexual behavior (<xref ref-type="bibr" rid="B18">18</xref>) as well as immediate gratification behaviors (<xref ref-type="bibr" rid="B19">19</xref>) and BPD traits (<xref ref-type="bibr" rid="B10">10</xref>). Lastly, <italic>Negative Urgency</italic> has been linked with problematic substance use (<xref ref-type="bibr" rid="B9">9</xref>), BPD traits (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B10">10</xref>), depression and anxiety (<xref ref-type="bibr" rid="B8">8</xref>), suicidal behaviors (<xref ref-type="bibr" rid="B13">13</xref>), eating disorders (e.g., binging and purging) (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B20">20</xref>), and aggression (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B15">15</xref>).</p>
<p>Since the development of the UPPS-P model (<xref ref-type="bibr" rid="B16">16</xref>, <xref ref-type="bibr" rid="B21">21</xref>, <xref ref-type="bibr" rid="B22">22</xref>), recent studies found that the short 20-items version of the UPPS-P scale preserves its good psychometric properties (<xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B23">23</xref>&#x02013;<xref ref-type="bibr" rid="B26">26</xref>). More specifically, they showed, using various psychopathological scales, that the short version of the UPPS-P (S-UPPS-P) has acceptable to good internal consistency (Cronbach&#x00027;s alpha ranging from 0.61 to 0.88) (<xref ref-type="bibr" rid="B23">23</xref>&#x02013;<xref ref-type="bibr" rid="B26">26</xref>); good to very good test-retest reliability (Correlation coefficients of &#x0007E;0.87) (<xref ref-type="bibr" rid="B23">23</xref>), as well as similar factorial structure to the UPPS-P (<xref ref-type="bibr" rid="B23">23</xref>&#x02013;<xref ref-type="bibr" rid="B26">26</xref>) and good external validity (<xref ref-type="bibr" rid="B23">23</xref>, <xref ref-type="bibr" rid="B25">25</xref>, <xref ref-type="bibr" rid="B26">26</xref>).</p>
<p>The transdiagnostic characteristic of impulsivity is highly relevant for clinicians regarding the understanding and the treatment of different forms of psychopathologies and problematic behaviors. In this sense, impulsivity constitutes a key target for clinical interventions (<xref ref-type="bibr" rid="B27">27</xref>). The UPPS-P model has attempted to clarify issues regarding the heterogeneity of impulsivity by presenting a strong and stable factorial structure. Considering the fact that the five dimensions of the UPPS-P are all specifically associated with distinct psychopathologies and problematic behaviors, the short version of the UPPS-P scale could be a suitable solution to overcome difficulties concerning the identification and the management of the broad spectrum of impulsivity-related problems in psychiatric patients. Along these lines, to our knowledge, no prior study has examined the psychometric properties of the UPPS-P scale amongst unstable psychiatric populations such as those in emergency department (ED). The objective of this current study is to examine the psychometric properties of the French version of the S-UPPS-P (<xref ref-type="bibr" rid="B23">23</xref>) in a large sample of adult psychiatric patients evaluated in a psychiatric ED. More precisely, we aimed to investigate the internal consistency, the construct validity, the test-retest reliability of the S-UPPS-P, as well as correlations between its subscales and a substance misuse measure, in this particular setting across psychiatric diagnoses and gender.</p>
</sec>
<sec sec-type="methods" id="s2">
<title>Methodology</title>
<sec>
<title>Sample Description</title>
<p>The sample was taken from the Signature Bank of the <italic>Institut Universitaire en Sant&#x000E9; Mentale de Montr&#x000E9;al</italic> (IUSMM). Research nurses approached 1,862 eligible participants from the psychiatric emergency of the IUSMM. Of this number, 1,218 agreed to participate in the study. In the current validation study, 1,097 patients have accepted to participate. This is referred to as Time 1 (T1). French version of the S-UPPS-P used in the current study is taken from Bilieux et al. (<xref ref-type="bibr" rid="B23">23</xref>). These authors used forward-, consensus, and back-translation steps to assess the quality of the translation. Only 25 participants answered the questionnaire in the original English version. A subsample of 148 participants answered the questionnaire a second time within a 30-day interval right before leaving the hospital. This is referred to as T2. For details on the characteristics of patients at T1 and T2, please refer to <xref ref-type="supplementary-material" rid="SM1">Supplementary Tables 1, 2</xref>.</p>
<p>Our sample was mainly characterized by individuals with substance use disorders (SUDs) (<italic>N</italic> &#x0003D; 83), psychotic disorders (<italic>N</italic> &#x0003D; 429), mood disorders (<italic>N</italic> &#x0003D; 350), anxiety disorders (<italic>N</italic> &#x0003D; 104), personality disorders (PDs) (<italic>N</italic> &#x0003D; 115), and other psychiatric disorders (<italic>N</italic> &#x0003D; 16). Over half were men (<italic>N</italic> &#x0003D; 655 [59.7%]) with a mean (SD) age of 40.4 (14.1) years. All participants signed a detailed consent form, and the study was approved by the local ethics committee in accordance with the <italic>Declaration of Helsinki</italic>.</p>
</sec>
<sec>
<title>Instruments</title>
<sec>
<title>Psychiatric Diagnoses</title>
<p>Research nurses collected patient&#x00027;s psychiatric diagnoses from medical records. Psychiatric diagnoses were established by psychiatrists on the ward, and were coded according to the World Health Organization International Classification of Disease (ICD-10) (<xref ref-type="bibr" rid="B28">28</xref>). In this article, we used 6 of the categories of mental disorder (F00&#x02013;F99): (1) Substance related disorders (F10-F19), (2) Schizophrenia and psychotic disorders (F20&#x02013;F29), (3) Mood disorders (F30&#x02013;F39), (4) Anxious disorders (F40&#x02013;F49), (5) Personality Disorders (F60&#x02013;F69), and (6) Others (F00&#x02013;F09, F50&#x02013;59, and F70&#x02013;F99). As shown in <xref ref-type="supplementary-material" rid="SM1">Supplementary Table 1</xref>, more than 70% of patients were treated primarily for psychotic and mood disorders.</p>
</sec>
<sec>
<title>Impulsive Behavior Scale</title>
<p>The <italic>Impulsive behavior scale</italic> (S-UPPS-P) is an instrument composed of 20 items rated on a four-point Likert scale (<xref ref-type="bibr" rid="B23">23</xref>): (1) <italic>disagree strongly</italic>, (2) <italic>disagree some</italic>, (3) <italic>agree some</italic>, and (4) <italic>agree strongly</italic>. Five scales were computed by adding the 4 items corresponding to each scale: (1) negative urgency (NU), (2) positive urgency (PU), (3) sensation seeking (SS), (4) lack of perseveration (PE), and (5) lack of premeditation (PR). Each scale ranges from 4 to 16. The description of each scale by main psychiatric diagnosis and sex is indicated in <xref ref-type="supplementary-material" rid="SM1">Supplementary Table 3</xref>. The S-UPPS-P questionnaire is shown in <xref ref-type="supplementary-material" rid="SM1">Appendix 1</xref>.</p>
</sec>
<sec>
<title>Drug Abuse Screening Test (DAST-10)</title>
<p>The Drug abuse screening test is a 10-item check list. The items are dichotomous: (0) no, (1) yes. The total scale is the sum of the 10 items resulting in a scale of 0&#x02013;10.</p>
</sec>
</sec>
<sec>
<title>Statistical Analyses</title>
<p>Analyses were all performed in R v3.3.0 (<xref ref-type="bibr" rid="B29">29</xref>). We used the <italic>psych</italic> package (<xref ref-type="bibr" rid="B30">30</xref>) for reliability analyses and the <italic>lavaan</italic> package (<xref ref-type="bibr" rid="B31">31</xref>) for Structural Equation modeling (SEM).</p>
<sec>
<title>Internal Consistency</title>
<p>To evaluate the internal consistency of the S-UPPS-P, Cronbach alphas (<xref ref-type="bibr" rid="B32">32</xref>) were estimated for each of the five subscales: negative urgency (NU), positive urgency (PU), sensation seeking (SS), lack of perseveration (PE), lack of premeditation (PR). We tested first for all participants and then by sex and main psychiatric diagnosis.</p>
</sec>
<sec>
<title>Construct Validity</title>
<p>Following the work made by Billieux et al. (<xref ref-type="bibr" rid="B23">23</xref>), confirmatory factor analyses using a probit link were performed to confirm the structure of the S-UPPS-P. Four factorial models were compared: (1) a single-factor model (Model 1) in which all 20 items loaded on a unique &#x0201C;impulsivity factor,&#x0201D; (2) a five factor model (Model 2) representing the five subscales of the S-UPPS-P (see <xref ref-type="supplementary-material" rid="SM1">Supplementary Figure 1</xref>), (3) a three factor model (Model 3) represented by three latent variables: urgency, sensation seeking and lack of conscientiousness and this three factor model, adding hierarchical structure: urgency (positive and negative urgency as lower order factors), sensation seeking and lack of conscientiousness (lack of premeditation and perseverance as lower order factors). Membership in one of the 4 Likert categories was assigned using three thresholds and a latent variable for each items of the UPPS-P. Model were adjusted using lavaan package (<xref ref-type="bibr" rid="B31">31</xref>) in R (<xref ref-type="bibr" rid="B29">29</xref>). Group analyses by gender were examined to test for measurement invariance across sexes with ordered categorical variable (<xref ref-type="bibr" rid="B33">33</xref>).</p>
</sec>
<sec>
<title>Test-Retest Reliability</title>
<p>As described previously in the sample description, a subsample of 148 participants answered the UPPS-P questionnaire a second time just before their release from the hospital. Only the participants who answered the questionnaire within 30 days of their admissions were selected. The mean (&#x000B1; SD) time between emergency admission (T1) and hospital release (T2) was 14.1 &#x000B1; 6.7 days. Correlations and intra-class correlations (ICC) were estimated to assess the stability of the impulsive behavior questionnaire.</p>
</sec>
<sec>
<title>Correlations With a Substance Misuse Measure (DAST-10)</title>
<p>An association has been regularly observed between SUDs and impulsivity, specifically sensation seeking (<xref ref-type="bibr" rid="B34">34</xref>). By using a confirmatory factor analysis, we tested for relationships between the impulsivity measures and substance use (as measured with the DAST-10), since both constructs are theoretically and empirically related.</p>
</sec>
<sec>
<title>Comparisons of Mean Differences of S-UPPS-P Subscales Between Diagnostic Categories</title>
<p>To better understand differences in S-UPPS-P subscales between diagnostic categories, we performed analysis of variance (ANOVA) <italic>post hoc</italic> pairwise comparisons tests, corrected with Tukey test for multiple comparisons.</p>
</sec>
</sec>
</sec>
<sec sec-type="results" id="s3">
<title>Results</title>
<sec>
<title>Internal Consistency</title>
<p>Cronbach&#x00027;s alpha for all the participants varied between 0.70 and 0.81 indicating an acceptable to a good reliability of the S-UPPS-P questionnaire. As illustrated in <xref ref-type="table" rid="T1">Table 1</xref>, each dropped item did not improve the Cronbach&#x00027;s alpha.</p>
<table-wrap position="float" id="T1">
<label>Table 1</label>
<caption><p>Cronbach alpha for the full sample with 95% confidence interval.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Negative Urgency</bold></th>
<th valign="top" align="center"><bold>0.79 (0.77, 0.81)</bold></th>
<th valign="top" align="left"><bold>Lack of Perseveration</bold></th>
<th valign="top" align="center"><bold>0.81 (0.80, 0.83)</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">With q4 dropped</td>
<td valign="top" align="center">0.76</td>
<td valign="top" align="left">With q5 dropped</td>
<td valign="top" align="center">0.80</td>
</tr>
<tr>
<td valign="top" align="left">With q7 dropped</td>
<td valign="top" align="center">0.73</td>
<td valign="top" align="left">With q8 dropped</td>
<td valign="top" align="center">0.73</td>
</tr>
<tr>
<td valign="top" align="left">With q12 dropped</td>
<td valign="top" align="center">0.73</td>
<td valign="top" align="left">With q11 dropped</td>
<td valign="top" align="center">0.75</td>
</tr>
<tr>
<td valign="top" align="left">With q17 dropped</td>
<td valign="top" align="center">0.75</td>
<td valign="top" align="left">With q16 dropped</td>
<td valign="top" align="center">0.78</td>
</tr>
<tr style="border-top: thin solid #000000;">
<td valign="top" align="left">Positive Urgency</td>
<td valign="top" align="center">0.70 (0.68, 0.73)</td>
<td valign="top" align="left">Lack of Premeditation</td>
<td valign="top" align="center">0.79 (0.76, 0.81)</td>
</tr>
<tr style="border-top: thin solid #000000;">
<td valign="top" align="left">With q2 dropped</td>
<td valign="top" align="center">0.64</td>
<td valign="top" align="left">With q1 dropped</td>
<td valign="top" align="center">0.75</td>
</tr>
<tr>
<td valign="top" align="left">With q10 dropped</td>
<td valign="top" align="center">0.69</td>
<td valign="top" align="left">With q6 dropped</td>
<td valign="top" align="center">0.73</td>
</tr>
<tr>
<td valign="top" align="left">With q15 dropped</td>
<td valign="top" align="center">0.60</td>
<td valign="top" align="left">With q13 dropped</td>
<td valign="top" align="center">0.72</td>
</tr>
<tr>
<td valign="top" align="left">With q20 dropped</td>
<td valign="top" align="center">0.62</td>
<td valign="top" align="left">With q19 dropped</td>
<td valign="top" align="center">0.74</td>
</tr>
<tr style="border-top: thin solid #000000;">
<td valign="top" align="left">Sensation Seeking</td>
<td valign="top" align="center">0.77 (0.75, 0.79)</td>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left" style="border-top: thin solid #000000;">With q3 dropped</td>
<td valign="top" align="center" style="border-top: thin solid #000000;">0.74</td>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">With q9 dropped</td>
<td valign="top" align="center">0.69</td>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">With q14 dropped</td>
<td valign="top" align="center">0.73</td>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">With q18 dropped</td>
<td valign="top" align="center">0.69</td>
<td/>
<td/>
</tr>
</tbody>
</table>
</table-wrap>
<p><xref ref-type="table" rid="T2">Table 2</xref> shows the results on the reliability of the UPPS-P by sex and main psychiatric diagnosis. In most subgroups, the 95% confidence intervals intersected with each other or are above the total alpha. Only the subgroup composed of women with psychotic disorders had a lower Cronbach&#x00027;s alpha. <xref ref-type="fig" rid="F1">Figure 1</xref> displays graphically the different confidence intervals. Some confidence intervals were very large due to a smaller prevalence of certain psychiatric disorders, such as SUDs and other psychiatric illnesses (F00&#x02013;F09, F50&#x02013;59, and F70&#x02013;F99 in ICD-10). These results showed that the reliability of the UPPS is constant across psychiatric diagnoses and sexes.</p>
<table-wrap position="float" id="T2">
<label>Table 2</label>
<caption><p>S-UPPS-P reliability (Cronbach &#x003B1;) by sex and main diagnostic.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Main diagnostic</bold></th>
<th valign="top" align="center"><bold>Female</bold></th>
<th valign="top" align="center"><bold>Male</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left" colspan="3" style="background-color:#bdbec1"><bold>NEGATIVE URGENCY</bold></td>
</tr>
<tr>
<td valign="top" align="left">Substance use</td>
<td valign="top" align="center">0.79 (0.63, 0.95)</td>
<td valign="top" align="center">0.82 (0.75, 0.89)</td>
</tr>
<tr>
<td valign="top" align="left">Psychotic disorder</td>
<td valign="top" align="center">0.69 (0.60, 0.78)</td>
<td valign="top" align="center">0.74 (0.70, 0.79)</td>
</tr>
<tr>
<td valign="top" align="left">Mood disorder</td>
<td valign="top" align="center">0.84 (0.80, 0.88)</td>
<td valign="top" align="center">0.73 (0.66, 0.79)</td>
</tr>
<tr>
<td valign="top" align="left">Anxious disorder</td>
<td valign="top" align="center">0.72 (0.59, 0.85)</td>
<td valign="top" align="center">0.90 (0.85, 0.94)</td>
</tr>
<tr>
<td valign="top" align="left">Personality disorder</td>
<td valign="top" align="center">0.76 (0.66, 0.85)</td>
<td valign="top" align="center">0.86 (0.79, 0.93)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">0.63 (0.22, 1.00)</td>
<td valign="top" align="center">0.77 (0.51, 1.00)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3" style="background-color:#bdbec1"><bold>POSITIVE URGENCY</bold></td>
</tr>
<tr>
<td valign="top" align="left">Substance use</td>
<td valign="top" align="center">0.66 (0.40, 0.92)</td>
<td valign="top" align="center">0.63 (0.49, 0.78)</td>
</tr>
<tr>
<td valign="top" align="left">Psychotic disorder</td>
<td valign="top" align="center">0.51 (0.38, 0.65)</td>
<td valign="top" align="center">0.63 (0.56, 0.70)</td>
</tr>
<tr>
<td valign="top" align="left">Mood disorder</td>
<td valign="top" align="center">0.69 (0.61, 0.77)</td>
<td valign="top" align="center">0.75 (0.69, 0.81)</td>
</tr>
<tr>
<td valign="top" align="left">Anxious disorder</td>
<td valign="top" align="center">0.75 (0.63, 0.86)</td>
<td valign="top" align="center">0.81 (0.73, 0.89)</td>
</tr>
<tr>
<td valign="top" align="left">Personality disorder</td>
<td valign="top" align="center">0.78 (0.70, 0.86)</td>
<td valign="top" align="center">0.83 (0.75, 0.92)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">0.91 (0.83, 0.99)</td>
<td valign="top" align="center">0.91 (0.81, 1.00)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3" style="background-color:#bdbec1"><bold>SENSATION SEEKING</bold></td>
</tr>
<tr>
<td valign="top" align="left">Substance use</td>
<td valign="top" align="center">0.86 (0.75, 0.97)</td>
<td valign="top" align="center">0.69 (0.56, 0.81)</td>
</tr>
<tr>
<td valign="top" align="left">Psychotic disorder</td>
<td valign="top" align="center">0.74 (0.67, 0.82)</td>
<td valign="top" align="center">0.70 (0.64, 0.75)</td>
</tr>
<tr>
<td valign="top" align="left">Mood disorder</td>
<td valign="top" align="center">0.83 (0.79, 0.87)</td>
<td valign="top" align="center">0.81 (0.77, 0.86)</td>
</tr>
<tr>
<td valign="top" align="left">Anxious disorder</td>
<td valign="top" align="center">0.69 (0.55, 0.88)</td>
<td valign="top" align="center">0.72 (0.60, 0.84)</td>
</tr>
<tr>
<td valign="top" align="left">Personality disorder</td>
<td valign="top" align="center">0.81 (0.73, 0.88)</td>
<td valign="top" align="center">0.67 (0.52, 0.83)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">0.84 (0.65, 1.00)</td>
<td valign="top" align="center">0.37 (0.00, 0.98)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3" style="background-color:#bdbec1"><bold>LACK OF PERSEVERATION</bold></td>
</tr>
<tr>
<td valign="top" align="left">Substance use</td>
<td valign="top" align="center">0.91 (0.84, 0.98)</td>
<td valign="top" align="center">0.76 (0.66, 0.85)</td>
</tr>
<tr>
<td valign="top" align="left">Psychotic disorder</td>
<td valign="top" align="center">0.76 (0.69, 0.83)</td>
<td valign="top" align="center">0.77 (0.73, 0.82)</td>
</tr>
<tr>
<td valign="top" align="left">Mood disorder</td>
<td valign="top" align="center">0.87 (0.83, 0.90)</td>
<td valign="top" align="center">0.81 (0.76, 0.85)</td>
</tr>
<tr>
<td valign="top" align="left">Anxious disorder</td>
<td valign="top" align="center">0.83 (0.75, 0.91)</td>
<td valign="top" align="center">0.79 (0.70, 0.88)</td>
</tr>
<tr>
<td valign="top" align="left">Personality disorder</td>
<td valign="top" align="center">0.84 (0.78, 0.90)</td>
<td valign="top" align="center">0.87 (0.81, 0.94)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">0.87 (0.73, 1.00)</td>
<td valign="top" align="center">0.51 (0.02, 0.99)</td>
</tr>
<tr>
<td valign="top" align="left" colspan="3" style="background-color:#bdbec1"><bold>LACK OF PREMEDITATION</bold></td>
</tr>
<tr>
<td valign="top" align="left">Substance use</td>
<td valign="top" align="center">0.70 (0.46, 0.94)</td>
<td valign="top" align="center">0.81 (0.73, 0.88)</td>
</tr>
<tr>
<td valign="top" align="left">Psychotic disorder</td>
<td valign="top" align="center">0.65 (0.55, 0.75)</td>
<td valign="top" align="center">0.78 (0.74, 0.82)</td>
</tr>
<tr>
<td valign="top" align="left">Mood disorder</td>
<td valign="top" align="center">0.79 (0.74, 0.85)</td>
<td valign="top" align="center">0.73 (0.66, 0.79)</td>
</tr>
<tr>
<td valign="top" align="left">Anxious disorder</td>
<td valign="top" align="center">0.75 (0.63, 0.87)</td>
<td valign="top" align="center">0.82 (0.75, 0.90)</td>
</tr>
<tr>
<td valign="top" align="left">Personality disorder</td>
<td valign="top" align="center">0.80 (0.72, 0.87)</td>
<td valign="top" align="center">0.86 (0.78, 0.93)</td>
</tr>
<tr>
<td valign="top" align="left">Other</td>
<td valign="top" align="center">0.63 (0.18, 1.00)</td>
<td valign="top" align="center">0.70 (0.45, 0.95)</td>
</tr>
</tbody>
</table>
</table-wrap>
<fig id="F1" position="float">
<label>Figure 1</label>
<caption><p>Cronbach alpha&#x00027;s intervals of S-UPPS-P subscales per diagnosis and sex (<italic>n</italic> &#x0003D; 1097).</p></caption>
<graphic xlink:href="fpsyt-10-00139-g0001.tif"/>
</fig>
</sec>
<sec>
<title>Construct Validity</title>
<p><xref ref-type="table" rid="T3">Table 3</xref> demonstrates the results of the 4 model comparisons. The best fitting model using CFI, TLI, RMSEA and SRMR was obtained with the five-factor model (Model 2). This model had a good fit (<xref ref-type="bibr" rid="B35">35</xref>), CFI &#x0003D; 0.98 &#x0003E; 0.90 and the upper part of the 90% confidence interval of the RMSEA was lower than 0.08, RMSEA 90% C.I. &#x0003D; (0.065, 0.073). The three-factor hierarchical model (Model 4) also showed good fit of the data (RMSEA &#x0003D; 0.082 (CI: 0.078&#x02013;0.086), CFI &#x0003D; 0.97, TLI &#x0003D; 0.96 SRMR &#x0003D; 0.078). As shown in <xref ref-type="table" rid="T3">Table 3</xref>, the two other models provided worse model fits.</p>
<table-wrap position="float" id="T3">
<label>Table 3</label>
<caption><p>Comparison of the 4 factorial models.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Model</bold></th>
<th valign="top" align="center"><bold>CFI</bold></th>
<th valign="top" align="center"><bold>TLI</bold></th>
<th valign="top" align="center"><bold>RMSEA (90% C.I.)</bold></th>
<th valign="top" align="center"><bold>SRMR</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">1</td>
<td valign="top" align="center">0.765</td>
<td valign="top" align="center">0.738</td>
<td valign="top" align="center">0.209 (0.205, 0.213)</td>
<td valign="top" align="center">0.170</td>
</tr>
<tr>
<td valign="top" align="left">2</td>
<td valign="top" align="center">0.976</td>
<td valign="top" align="center">0.971</td>
<td valign="top" align="center">0.069 (0.065, 0.073)</td>
<td valign="top" align="center">0.066</td>
</tr>
<tr>
<td valign="top" align="left">3</td>
<td valign="top" align="center">0.948</td>
<td valign="top" align="center">0.941</td>
<td valign="top" align="center">0.100 (0.096, 0.103)</td>
<td valign="top" align="center">0.089</td>
</tr>
<tr>
<td valign="top" align="left">4</td>
<td valign="top" align="center">0.965</td>
<td valign="top" align="center">0.959</td>
<td valign="top" align="center">0.082 (0.078, 0.086)</td>
<td valign="top" align="center">0.078</td>
</tr>
</tbody>
</table>
</table-wrap>
<p>The 5-factor model, as shown in <xref ref-type="fig" rid="F2">Figure 2</xref>, is formed by negative urgency (NU), positive urgency (PU), sensation seeking (SS), lack of perseverance (PE) as well as lack of premeditation (PR). We also performed a multi-group analysis by sex to test for measurement invariance. Measurement invariance was tested for sex using the procedure by Millsap and Yun-Tein (<xref ref-type="bibr" rid="B33">33</xref>) for ordered categorical variable. First comparison between the configural model and the equal loadings model using scaled chi-squared differences (<xref ref-type="bibr" rid="B36">36</xref>) gave a statistically significant differences &#x00394;<inline-formula><mml:math id="M1"><mml:msubsup><mml:mrow><mml:mo>&#x003C7;</mml:mo></mml:mrow><mml:mrow><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>15</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msubsup></mml:math></inline-formula> &#x0003D; 27.2, <italic>p</italic> &#x0003D; 0.0275 but the difference in CFI and TLI was very small (&#x0007E;0.001). By freeing loadings of item 6 (PR: &#x0201C;My thinking is usually careful and purposeful&#x0201D;), and item 10 (PU: &#x0201C;When overjoyed, I feel like I can&#x00027;t stop myself from going overboard&#x0201D;) the difference with the configural models were no longer statistically significant &#x00394;<inline-formula><mml:math id="M2"><mml:msubsup><mml:mrow><mml:mo>&#x003C7;</mml:mo></mml:mrow><mml:mrow><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>18</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msubsup></mml:math></inline-formula> &#x0003D; 18.1, <italic>p</italic> &#x0003D; 0.1533. When we compared the partially freed loadings model to the fixed thresholds model the difference was statistically significant &#x00394;<inline-formula><mml:math id="M3"><mml:msubsup><mml:mrow><mml:mo>&#x003C7;</mml:mo></mml:mrow><mml:mrow><mml:mrow><mml:mo stretchy="false">(</mml:mo><mml:mrow><mml:mn>35</mml:mn></mml:mrow><mml:mo stretchy="false">)</mml:mo></mml:mrow></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msubsup></mml:math></inline-formula> &#x0003D; 67.3, <italic>p</italic> &#x0003C; 0.001. We stopped invariance testing at this step because of the large chi-square differences. The difference was mostly driven by the sex difference on the second and third threshold of item 10 which was respectively 0.333 and 0.346. This indicates that men over reported item 10 even when conditioned on the positive urgency factor.</p>
<fig id="F2" position="float">
<label>Figure 2</label>
<caption><p>Five-factor model structure of the S-UPPS-P.</p></caption>
<graphic xlink:href="fpsyt-10-00139-g0002.tif"/>
</fig>
</sec>
<sec>
<title>Test-Retest Reliability</title>
<p>Some participants were followed through their clinical pathways. We analyzed responses from participants who answered within 30 days of their original assessment just before they were released from the hospital. Results are presented in <xref ref-type="table" rid="T4">Table 4</xref>. The total score had a good test-retest reliability according to the correlation and intra-class correlation coefficients which were both around 0.60 and above. The scores ranged from 0.4 to 1.0 unit lower at Time 2.</p>
<table-wrap position="float" id="T4">
<label>Table 4</label>
<caption><p>Test-retest reliability (<italic>N</italic> &#x0003D; 148) for the impulsive behavior score within 30 days.</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>Measure</bold></th>
<th valign="top" align="center"><bold>(T1) mean &#x000B1; sd</bold></th>
<th valign="top" align="center"><bold>(T2) mean &#x000B1; sd</bold></th>
<th valign="top" align="center"><bold><italic>r</italic> (T1, T2)</bold></th>
<th valign="top" align="center"><bold>ICC (T1, T2)</bold></th>
</tr>
</thead>
<tbody>
<tr>
<td valign="top" align="left">Negative urgency</td>
<td valign="top" align="center">10.3 &#x000B1; (3.4)</td>
<td valign="top" align="center">9.1 &#x000B1; (3.0)</td>
<td valign="top" align="center">0.61<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.56<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Positive urgency</td>
<td valign="top" align="center">11.0 &#x000B1; (3.0)</td>
<td valign="top" align="center">10.1 &#x000B1; (2.7)</td>
<td valign="top" align="center">0.60<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.57<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Sensation seeking</td>
<td valign="top" align="center">9.7 &#x000B1; (3.3)</td>
<td valign="top" align="center">9.2 &#x000B1; (3.2)</td>
<td valign="top" align="center">0.64<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.63<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Lack of perseveration</td>
<td valign="top" align="center">7.4 &#x000B1; (2.8)</td>
<td valign="top" align="center">7.2 &#x000B1; (2.7)</td>
<td valign="top" align="center">0.66<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.66<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">Lack of premeditation</td>
<td valign="top" align="center">7.6 &#x000B1; (2.7)</td>
<td valign="top" align="center">7.2 &#x000B1; (2.4)</td>
<td valign="top" align="center">0.65<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
<td valign="top" align="center">0.64<xref ref-type="table-fn" rid="TN1"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>&#x0002A; p &#x0003C; 0.05</italic></p>
<p><italic>&#x0002A;&#x0002A; p &#x0003C; 0.01</italic></p>
<fn id="TN1">
<label>&#x0002A;&#x0002A;&#x0002A;</label>
<p><italic>p &#x0003C; 0.001</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
<sec>
<title>Correlations With a Substance Misuse Measure (DAST-10)</title>
<p>We tested correlations between the five subscales of the S-UPPS-P and a substance use measure (DAST-10). We expected that patient&#x00027;s impulsivity score, specifically the sensation seeking subscale score, would be associated with the DAST total score. This was tested using a CFA with the factor structure described earlier. Results of the CFA of the 5 dimensions of the S-UPPS-P regressed on the DAST-10 showed that sensation seeking correlated with substance use (r &#x0003D; 0.37, <italic>p</italic> &#x0003C; 0.001). A trend was observed concerning a positive association between Lack of premeditation and substance use (<italic>r</italic> &#x0003D; 0.13, <italic>p</italic> &#x0003D; 0.053). These results remained statistically significant after the inclusion of age and sex as adjustment variables (see <xref ref-type="fig" rid="F3">Figure 3</xref>).</p>
<fig id="F3" position="float">
<label>Figure 3</label>
<caption><p>Results of the confirmatory factor analysis (CFA) to test the link between substance use (DAST-10) and the impulsive behavior questionnaire (S-UPPS-P) dimensions: negative urgency (NU), positive urgency (PU), lack of perseveration (PE), lack of premeditation (PR); Age and Sex are added as adjustment variables; &#x0002A; &#x0003C;0.05; &#x0002A;&#x0002A; &#x0003C;0.01; &#x0002A;&#x0002A;&#x0002A; &#x0003C;0.001.</p></caption>
<graphic xlink:href="fpsyt-10-00139-g0003.tif"/>
</fig>
</sec>
<sec>
<title>Comparisons of Mean Differences of S-UPPS-P Subscales Between Diagnostic Categories</title>
<p>Results suggest significant differences between diagnostic categories across every S-UPPS-P subscale, as shown in <xref ref-type="table" rid="T5">Table 5</xref>. More specifically, pairwise <italic>post hoc</italic> tests showed that participants with a PD scored significantly higher in Negative Urgency, Positive Urgency, Sensation Seeking, Lack of Premeditation, and Lack of Perseverance subscales than almost every other diagnostic category (see <xref ref-type="supplementary-material" rid="SM1">Supplementary Table 4</xref>). In comparison to patients with a SUD, those with a PD scored significantly higher only on Lack of Premeditation (<italic>p</italic> &#x0003D; 0.002) and Lack of Perseverance (<italic>p</italic> &#x0003D; 0.019).</p>
<table-wrap position="float" id="T5">
<label>Table 5</label>
<caption><p>Comparisons of mean differences of S-UPPS-P subscales between diagnostic categories (<italic>n</italic> &#x0003D; 1,097).</p></caption>
<table frame="hsides" rules="groups">
<thead><tr>
<th valign="top" align="left"><bold>S-UPPS-P subscales</bold></th>
<th valign="top" align="center"><bold>Substance use disorders (<italic>n</italic> &#x0003D; 83)</bold></th>
<th valign="top" align="center"><bold>Psychotic disorders (<italic>n</italic> &#x0003D; 429)</bold></th>
<th valign="top" align="center"><bold>Mood disorders (<italic>n</italic> &#x0003D; 350)</bold></th>
<th valign="top" align="center"><bold>Anxiety disorders (<italic>n</italic> &#x0003D; 104)</bold></th>
<th valign="top" align="center"><bold>Personality disorders (<italic>n</italic> &#x0003D; 115)</bold></th>
<th valign="top" align="center"><bold>Other disorders (<italic>n</italic> &#x0003D; 16)</bold></th>
<th valign="top" align="center"><bold><italic>F-Statistics</italic></bold></th>
</tr>
</thead>
<tbody>
<tr>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
<td/>
</tr>
<tr>
<td valign="top" align="left">NU</td>
<td valign="top" align="center">12.17 (3.09)</td>
<td valign="top" align="center">9.85 (3.21)</td>
<td valign="top" align="center">10.38 (3.30)</td>
<td valign="top" align="center">11.52 (3.31)</td>
<td valign="top" align="center">13.02 (2.86)</td>
<td valign="top" align="center">11.69 (3.40)</td>
<td valign="top" align="center">23.82<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">PU</td>
<td valign="top" align="center">12.04 (2.62)</td>
<td valign="top" align="center">10.43 (2.84)</td>
<td valign="top" align="center">10.67 (3.04)</td>
<td valign="top" align="center">11.03 (3.19)</td>
<td valign="top" align="center">12.56 (3.00)</td>
<td valign="top" align="center">12.12 (3.72)</td>
<td valign="top" align="center">12.82<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">SS</td>
<td valign="top" align="center">11.14 (2.92)</td>
<td valign="top" align="center">9.53 (3.24)</td>
<td valign="top" align="center">9.69 (3.53)</td>
<td valign="top" align="center">8.77 (2.91)</td>
<td valign="top" align="center">10.55 (3.18)</td>
<td valign="top" align="center">9.56 (3.10)</td>
<td valign="top" align="center">6.66<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">PR</td>
<td valign="top" align="center">8.25 (2.86)</td>
<td valign="top" align="center">7.26 (2.69)</td>
<td valign="top" align="center">7.40 (2.67)</td>
<td valign="top" align="center">8.09 (2.79)</td>
<td valign="top" align="center">9.74 (3.01)</td>
<td valign="top" align="center">7.69 (2.52)</td>
<td valign="top" align="center">16.86<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
<tr>
<td valign="top" align="left">PE</td>
<td valign="top" align="center">7.70 (3.01)</td>
<td valign="top" align="center">7.70 (3.01)</td>
<td valign="top" align="center">7.49 (3.05)</td>
<td valign="top" align="center">7.71 (2.88)</td>
<td valign="top" align="center">9.03 (3.21)</td>
<td valign="top" align="center">7.12 (2.45)</td>
<td valign="top" align="center">16.86<xref ref-type="table-fn" rid="TN2"><sup>&#x0002A;&#x0002A;&#x0002A;</sup></xref></td>
</tr>
</tbody>
</table>
<table-wrap-foot>
<p><italic>Means and standard deviations are reported for each S-UPPS-P subscale by diagnostic categories. NU, Negative Urgency; PU, Positive Urgency; SS, Sensation Seeking; PR, Lack of Premeditation; PE, Lack of Perseverance; &#x0002A;p &#x0003C; 0.05; &#x0002A;&#x0002A;p &#x0003C; 0.01;</italic></p>
<fn id="TN2">
<label>&#x0002A;&#x0002A;&#x0002A;</label>
<p><italic>p &#x0003C; 0.001</italic>.</p></fn>
</table-wrap-foot>
</table-wrap>
</sec>
</sec>
<sec sec-type="discussion" id="s4">
<title>Discussion</title>
<p>The present study examined the psychometric properties of the S-UPPS-P questionnaire (<xref ref-type="bibr" rid="B23">23</xref>) which was administered in a psychiatric ED. Generally, results demonstrated that the S-UPPS-P has good psychometric properties across psychiatric diagnoses and sexes in this specific setting. Moreover, Cronbach&#x00027; alphas supported acceptable to good internal consistency within dimensions: negative urgency (0.79), positive urgency (0.70), lack of perseveration (0.81), lack of premeditation (0.79), and sensation seeking (0.77). The internal consistency reliability was found to be constant across psychiatric diagnoses and sexes but was lower in the subgroup composed of women with psychotic disorders. The reasons for this latter observation are elusive. Furthermore, CFA confirmed similar structures consistent with previous studies (five-factor model: 25, 26 and three-factor hierarchical model: 23). Correlations and intra-class correlation coefficients indicated that the S-UPPS-P had a good test-retest reliability. While below the usual cut-off (&#x0003E;0.70), results were good considering the psychological instability of patients admitted in a psychiatric ED (T1) in comparison to their release (T2). Finally, by testing correlations with a substance misuse measure, we observed a strong association between substance use and sensation seeking. These latter findings are similar to those of previous studies on impulsivity in SUD populations (<xref ref-type="bibr" rid="B34">34</xref>), and further justify the use of factors rather the use of a broad UPPS total score. Additionally, our results suggest that the distinction between impulsive behavior factors seems to be determinant in the comprehension of specific psychopathology and inadequate behaviors such as drug misuse.</p>
<p>A significant finding in our study is that we were able to replicate the validity of the theory-driven factor structure of the UPPS-P model across both psychiatric diagnoses and gender within a psychiatric ED. Indeed, both structures has been identified in general population samples using French (<xref ref-type="bibr" rid="B23">23</xref>), English (<xref ref-type="bibr" rid="B25">25</xref>), Spanish (<xref ref-type="bibr" rid="B24">24</xref>), and Italian (<xref ref-type="bibr" rid="B26">26</xref>) versions of the S-UPPS-P. The five distinct, yet interrelated factors (positive urgency, negative urgency, lack of premeditation, lack of perseverance, and sensation seeking) have already shown valuable implications for psychiatric research since each dimension was strongly associated with specific psychopathologies. In fact, our study has shown that participants with a PD had significantly higher scores than those with a psychotic, a mood, or an anxiety disorder on almost every subscales of the S-UPPS-P, thus reflecting that impulsivity and its subcomponents are core features of personality disorders (<xref ref-type="bibr" rid="B8">8</xref>, <xref ref-type="bibr" rid="B10">10</xref>, <xref ref-type="bibr" rid="B16">16</xref>). However, patients with PD did not significantly differ from patients with a SUD on the sensation seeking or the urgency&#x00027;s subscales. In fact, earlier studies suggested that impulsivity is a shared risk factor for developing a PD and/or a SUD (<xref ref-type="bibr" rid="B37">37</xref>, <xref ref-type="bibr" rid="B38">38</xref>). While PDs and SUDs may share subcomponents of impulsivity, the non-statistically significant results could be explained by the fact that both disorders are highly heterogeneous and intercorrelated (<xref ref-type="bibr" rid="B39">39</xref>, <xref ref-type="bibr" rid="B40">40</xref>). Thus, different subtypes of individuals with a PD and/or a SUD may be associated with distinct subcomponents of impulsivity (<xref ref-type="bibr" rid="B41">41</xref>, <xref ref-type="bibr" rid="B42">42</xref>). Nonetheless, our results suggest that the short version of the UPPS-P scale preserved its good psychometric properties in a sample of unstable psychiatric patients. Therefore, research on psychiatric unstable patients could use the S-UPPS-P to better understand psychopathologies and their comorbidities.</p>
<p>While the S-UPPS-P displayed overall psychometric properties that were satisfactory, we found that the construct validity of the instrument was only weakly invariant across sexes. Although this result needs to be interpreted cautiously, it may have implications for future studies on the psychometric properties of the UPPS as well as on gender differences in impulsivity. Recently, a meta-analysis found that there were gender differences in impulsivity (<xref ref-type="bibr" rid="B43">43</xref>). Nevertheless, it has been subsequently argued by Cyders (<xref ref-type="bibr" rid="B44">44</xref>) that conclusions concerning gender differences in impulsivity might be premature, because the measurement invariance of impulsivity scales across sexes is largely unknown. This author investigated this issue regarding the UPPS-P in a sample of undergraduate and found a measurement invariance across sexes but found a higher reported level of sensation seeking in men when compared to woman (<xref ref-type="bibr" rid="B44">44</xref>). Our results suggest that the S-UPPS-P is partially invariant across sexes when administered to psychiatric patients in an ED. More specifically, we found that item 10 of the positive urgency subscale was overrated by men. This suggest that, in this particular setting, there could be a bias in positive urgency response between sexes. Therefore, future studies on sex differences regarding impulsivity should pay special attention to these subtle methodological issues.</p>
<p>Limitations in the current study need to be acknowledged. First, psychiatrist on the ward did not establish the diagnosis of psychiatric disorders with a validated instrument such as the Structure Clinical Interview for DSM-V. Also, we did not include another impulsivity scale (e.g., Barratt Impulsiveness Scale), nor measures related to the five subscales of the UPPS-P model. Therefore, future studies should seek to test the convergent validity of the UPPS-P. Finally, due to small sample sizes across diagnostic categories, we did not examine measurement invariance across diagnostic categories. However, this should be considered in future studies in order to assess the stability of the psychometric properties of the S-UPPS-P across psychiatric disorders.</p>
<p>On the other hand, the strengths of the current study include the administration of the S-UPPS-P to a large sample of patients in a specific clinical environment (e.g., psychiatric ED), the examination of several psychometric properties (e.g., internal consistency, construct validity, test-retest reliability, and correlations with a substance misuse measure), and the verification of the measurement invariance of the instrument across and sexes.</p>
</sec>
<sec sec-type="conclusions" id="s5">
<title>Conclusion</title>
<p>In conclusion, the current study showed that the S-UPPS-P is a valid questionnaire for psychiatric research in general, and for research on unstable psychiatric population (e.g., psychiatric ED). However, researchers should be aware that the S-UPPS-P might not be the scale with the most optimal psychometric properties for evaluating gender differences in sensation seeking.</p>
</sec>
<sec id="s6">
<title>Author Contributions</title>
<p>AD and SP designed the study and wrote the protocol. JD and OP managed the literature searches. C-&#x000C9;G undertook the statistical analysis. JD wrote the first draft of the manuscript. All authors contributed to and have approved the final manuscript.</p>
<sec>
<title>Conflict of Interest Statement</title>
<p>The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.</p>
</sec>
</sec>
</body>
<back>
<ack>
<p>The authors would like to thank the Signature Bank of the Institut Universitaire en Sant&#x000E9; Mentale de Montr&#x000E9;al (IUSMM) for the data collection. SP is holder of the Eli Lilly Chair Canada on schizophrenia research; AD is the holder of a Young Investigator Junior 1 Award from the Fonds de Recherche Qu&#x000E9;bec en Sant&#x000E9;.</p>
</ack>
<sec sec-type="supplementary-material" id="s7">
<title>Supplementary Material</title>
<p>The Supplementary Material for this article can be found online at: <ext-link ext-link-type="uri" xlink:href="https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00139/full#supplementary-material">https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00139/full#supplementary-material</ext-link></p>
<supplementary-material xlink:href="Data_Sheet_1.docx" id="SM1" mimetype="application/vnd.openxmlformats-officedocument.wordprocessingml.document" xmlns:xlink="http://www.w3.org/1999/xlink"/>
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<fn-group>
<fn id="fn0001"><p><sup>1</sup>The &#x0201C;jingle&#x0201D; fallacy refers to an assumption that two different constructs are the same because they have the same label; the &#x0201C;jangle&#x0201D; fallacy refers to an assumption that two identical constructs are different because they are labeled differently</p></fn>
</fn-group>
</back>
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