AUTHOR=Quadri Humair S. , Smaglo Brandon G. , Morales Shannon J. , Phillips Anna Chloe , Martin Aimee D. , Chalhoub Walid M. , Haddad Nadim G. , Unger Keith R. , Levy Angela D. , Al-Refaie Waddah B. 

TITLE=Gastric Adenocarcinoma: A Multimodal Approach

JOURNAL=Frontiers in Surgery

VOLUME=Volume 4 - 2017

YEAR=2017

URL=https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2017.00042

DOI=10.3389/fsurg.2017.00042

ISSN=2296-875X

ABSTRACT=Despite its declining incidence, gastric cancer remains a leading cause of cancer-related deaths worldwide. A multimodal approach to gastric cancer is critical to ensure optimal patient outcomes. Pre-therapy fine resolution contrast-enhanced cross-sectional imaging, endoscopic ultrasound and staging laparoscopy play an important role in patients with newly diagnosed ostensibly operable gastric cancer to avoid unnecessary non-therapeutic laparotomies. Currently, margin negative gastrectomy and adequate lymphadenectomy performed at high volume hospitals remain the backbone of gastric cancer treatment. Importantly, adequate gastric cancer surgery should be integrated in the setting of a multimodal treatment approach. Treatment for advanced gastric cancer continues to expand with the emergence of additional lines of systemic and targeted therapies.