Autoimmune Diseases: from molecular mechanisms to therapy development

Patrizia Leone, Nicola Susca, Vito Racanelli

Frontiers Media SA

Autoimmune diseases arise when the immune system mistakenly targets and damages the body’s cells...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Autoimmune Diseases,­CAR-T cells,­Nanoparticles,­Molecular mechanisms,­immunological tolerance,­Tregs,­Bregs

Mathematical Modeling in Discovery and Analysis of Immune Responses

Jaroslaw Smieja, Penelope Anne Morel, Urszula Foryś

Frontiers Media SA

Uncovering mechanisms regulating immune system responses is key to strengthening and redirecting...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: mathematical model,­dynamics,­Immune System,­Signaling Pathways,­Immunotherapy,­autoimmune disease,­Viral Immunology,­Systems Immunology

Risk and Protective Factors in the Natural History of Autoimmunity

Christine Gibson Parks, Esther Erdei, Frederick Miller

Frontiers Media SA

Growing evidence shows preclinical autoimmunity among individuals who later develop clinical...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Autoimmune disorders,­Autoimmunity,­Autoantibodies,­Risk factors,­biomarkers,­environment,­Genetics,­viral infections,­microbiome,­autoinflammatory conditions

Autoimmunity: novel insights and future perspectives

Constantin Caruntu, Monica Neagu, Mihaela Adriana Ilie, Ancuta Mihai

Frontiers Media SA

Autoimmunity was, is and will be considered a hot topic in scientific research. One strong argument...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Autoimmune Diseases,­Autoantibodies,­immunology,­Inflammation,­immune system mechanisms,­immunoregulatory proteins,­Genetic mutations,­biomarkers,­diagnosis,­Immunomodulatory therapies

Exploring autoimmune diseases and endocrine crosstalk

Alessandro Antonelli, Anette S. B. Wolff, Deepika Watts

Frontiers Media SA

The endocrine system is a network of glands that produce and release hormones essential to control...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Autoimmune Diseases,­type 1 diabetes,­Addison's disease,­Endocrine Autoimmune Diseases,­endocrine-disrupting chemicals (EDCs)

Case Reports in Autoimmune and Autoinflammatory Disorders

Jemima Albayda, Mattia Bellan, Gian Marco Ghiggeri, Chris Wincup

Frontiers Media SA

This Research Topic is the second volume of the “Case Reports in Autoimmune and Autoinflammatory...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: case reports,­Autoimmune,­autoinflammatory

Next Generation Therapeutic Modality to Cure Autoimmune Diseases

Ce Wang, Guobao Chen, Qi Wan, Feng Dong, Timothy Radstake, Asif Amin Dar, Sergio Piñ Piñeiro

Frontiers Media SA

Autoimmune diseases represent a significant medical challenge where the body's immune system...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: autoimmune disease,­cell therapy,­Gene Therapy,­gene editing,­siRNA,­Protein degraders,­CAR T,­regulatory T cells,­Nanoparticles,­biologics,­bispecific antibodies,­ADC,­Protac,­AbTAC,­LYTAC,­therapeutic immunization

Community Series in Advances in Pathogenesis and Therapies of Gout, volume II

Jixin Zhong, Lihua Duan, Ye Yang, Xiaoxia Zhu, Yuan Liu

Frontiers Media SA

This Research Topic is the second volume of the “Advances in Pathogenesis and Therapies of Gout”...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: Gout,­Inflammasome,­Self-solution,­Hyperuricemia,­Monosodium urate

Community Series in Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-based Therapies in the Management of Inflammatory Rheumatic Diseases, volume II

Eric Toussirot, Katarzyna Bogunia-Kubik, Philippe Saas

Frontiers Media SA

This Research Topic is the second volume of the “Recent Advances in Potential Biomarkers for...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: IRD,­Spondyloarthritis,­Rheumatoid arthritis,­biomarkers,­cell-based therapy