Pharmacological mechanisms of drugs affecting bone formation and bone resorption

Xiaofeng Zhu, Alex Zhong, Dongwei Zhang

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Bone formation,­Bone Resorption,­pharmacological mechanisms

Progress in Pathology and Drug Development of Metabolic Disease

Ping Zhou, Suhong Chen, Yang Ke, Kim Hei-Man Chow

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Drug research,­Pathogenesis,­Physiological condition,­Treatment technology,­metabolic disease

Quality control for efficacy and safety of herbal medicinal products

Jian-bo Yang, Zhichao Xu, Wei Cai, Yong Li, Wing Lam

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: herbal medicines,­Quality control standard,­Safety evaluation,­molecular identification,­Isolation and purification,­endogenous and exogenous toxic constituents,­limited standards

Purinergic pharmacology, volume II

Francisco Ciruela, Kenneth. A. Jacobson

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Fibrosis: Etiology, Pathophysiology, Measurements, and Therapy

Yuxia Zhao, Panpan Hao, Peizhe Wang, Fujian Lu, Yanping Liu

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Fibrosis,­rennin-angiotensin-aldosterone system,­Adams,­Ca2+ signaling,­Foxo,­AMPK

Targeted drug discovery in ectopic calcification: Mechanism, prospect, and clinical application

Kang Xu, Charareh Pourzand, Jing Xie, Anna Malashicheva

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Ectopic calcifications,­Osteogenic differentiation,­therapeutic drug screening,­Pharmacological studies,­translational medicine,­preclinical application and reports

Model-informed decision making in the preclinical stages of pharmaceutical research and development

Rui Li, Donald E. Mager, Alison Betts, Tristan Scott Maurer, Morgan Craig, David Z. D’Argenio

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Drug Discovery,­Modeling and Simulation,­decision-making,­preclinical-to-clinical translation

Sepsis: Basic, Clinical and Therapeutic Approaches

Hong Zhou, Yan Kang, Lefu Lan, Daolin Tang

Frontiers Media SA

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Sepsis,­Pathogenesis,­signal transduction pathway,­Treatment,­therapeutic strategies

Ocular Pharmacology: Recent Breakthroughs and Unmet Needs

Claudio Bucolo, Chiara M. Eandi, Mario Damiano Toro

Frontiers Media SA

The research on ocular pharmacology has increased significantly, over the past decade. More...

Science Pharmacology Experimental Pharmacology and Drug Discovery

Keywords: Ocular pharmacology,­Retinal Diseases,­Corneal Diseases,­Pharmacological Targets,­Ocular drug delivery systems,­Dry eye syndrome,­Glaucoma