Proficiency testing in Histocompatibility and Immunogenetics: current status and future perspectives

Kelley M. K. Hitchman, Martin Petrek, Milena Vraná, Jose Palacio-Gruber

Frontiers Media SA

Proficiency testing (PT) has been part of Immunogenetics since its early days. Starting from...

Science Genetics Immunogenetics

Keywords: Histocompatibility,­Immunogenetic Tests,­Quality control,­HLA-typing,­Chimerism testing,­cross-match,­HLA-antibody identification

Mendelian Randomization: the Study of Causal Relationships between Tumors and Underlying Pathogenic Factors

Ziheng Wang, Guangsheng Pei

Frontiers Media SA

The malignant tumor is a major global public health problem threatening human health. At present,...

Science Genetics Statistical Genetics and Methodology

Keywords: Mendelian randomization,­oncology,­GWAS,­randomized controlled trials,­phenotype,­Genotype

Mendelian Randomization: An Approach for Precision Medicine and Public Health

Triinu Peters, Xiaoqing Pan, Yi-Ju Li, Jiayue-Clara Jiang

Frontiers Media SA

Epidemiological studies have established various observational associations between modifiable...

Science Genetics Statistical Genetics and Methodology

Keywords: Mendelian randomization,­ Epidemiological studies,­ Mendel’s laws,­ genome-wide association studies (GWAS)

Understanding Molecular Mechanisms to Facilitate the Development of Biomarkers for Therapeutic Intervention in Gastrointestinal Diseases and Sepsis

Dipak Kumar Sahoo, Romy Monika Heilmann, Ashish Patel

Frontiers Media SA

This research topic aims to provide an overview of the most recent advancements in understanding...

Science Genetics Human and Medical Genomics

Keywords: gastrointestinal disorders,­Sepsis,­miRNA; ,­biomarkers;,­epigenetics;,­inflammatory bowel disease,­antimicrobial resistance,­One Health,­Cancer

Data governance in African health research: ELSI challenges and solutions

Donrich Thaldar, Simisola Oluwatoyin Akintola, Bonginkosi Shozi

Frontiers Media SA

Data protection legislation is increasingly being enacted in African countries. Additionally, the...

Science Genetics ELSI in Science and Genetics

Keywords: Data governance,­ELSI,­Africa,­health research,­Africanisation,­decolonisation,­rule-harmonisation,­Informed Consent,­Trust,­Multi-dimensional,­Regulation authority,­AI

Recent Advances in Causes, Diagnosis, and Therapeutics for Congenital Heart Defects

Xinxiu Xu, DongZhu Xu, Lu Han, Lisa J. Martin, Cecilia W. Lo

Frontiers Media SA

Congenital heart disease (CHD) is one of the most common major birth defects, yet its causes remain...

Science Genetics Genetics of Common and Rare Diseases

Keywords: congenital heart defects,­Genetic etiology,­Genetic Testing,­diagnosis,­single-cell functional genomics,­Evidence-based therapy,­Patient outcomes

Recent Advances in Understanding The Genetics of Immunological Disorders

Che Kang Lim, Jinqiao Sun, Hassan Abolhassani

Frontiers Media SA

Immunological disorders are diseases or conditions due to the dysfunction of the immune system....

Science Genetics Genetics of Common and Rare Diseases

Keywords: Immunological disorders,­Immunological deficiency syndromes,­Autoimmune Diseases,­Asthma,­allergy,­and Autoinflammatory syndromes,­Integrative study,­next generation sequencing,­multi-omics

Eighth CCF Bioinformatics Conference: CBC 2023

Fa Zhang, Wang Guohua, Xuefeng Cui, Min Li, Cui Jinghua

Frontiers Media SA

This Research Topic is part of a series with:

Science Genetics Computational Genomics