Host and Microbe Immunometabolic Chat: A New Era of Organismal Communication

Teresa Zelante, Marco Gargaro, Christiane A. Opitz, Pedro Moura Alves, Francesca Fallarino

Frontiers Media SA

The field of host-microbe immunometabolism is rapidly evolving, with a growing body of evidence...

Health Immunology Immunological Tolerance and Regulation

Keywords: Metabolites,­Postbiotics,­microbiome,­Immunometabolism,­tolerance,­Xenobiotic Receptors

The Application of Immune Checkpoint Inhibitors Combined with Chemotherapy in Tumor Immunotherapy

Hongfei Jiang, Qihui Zhou, Tengbo Yu, Chao Wang, Yueying Li

Frontiers Media SA

The combination of immune checkpoint inhibitors (ICIs) with chemotherapy has revolutionized cancer...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: immune checkpoint inhibitors,­chemotherapy,­cancer immunotherapy,­Drug Resistance,­Tumor Microenvironment

Immune Adaptations in Aquatic Species: Defenses, Gene Diversity, and Environmental Stressors

Antonio Figueras, Cristian Gallardo-Escárate, Jorge Galindo-Villegas, Valentina Valenzuela-Muñoz, Magalí Rey-Campos

Frontiers Media SA

Aquatic environments present unique challenges that require robust immune defenses for species...

Health Immunology Comparative Immunology

Keywords: Aquatic species,­immune response,­pathogen defense,­immunogenomics,­genetic diversity,­Climate Change,­Disease pathology

In-Vitro, In-Vivo, and Ex-Vivo Models of Ischemia-Reperfusion Injury in Lung Transplantation

Ilker Iskender, Chetan Pasrija, Nirmal S. Sharma

Frontiers Media SA

In the fourth decade of clinical practice, lung transplantation (LTx) continues to evolve. This is...

Health Immunology Alloimmunity and Transplantation

Keywords: ischemia-reperfusion injury,­Primary Graft Dysfunction,­Donor management,­Ex vivo lung perfusion,­Lung Transplantation

Biomarkers of Immunotoxicity from Immune Checkpoint Inhibitors

Jamie S. Lin, Sang T. Kim, Petra Huehnchen, Karthik Suresh

Frontiers Media SA

Immune checkpoint inhibitors (ICIs) have profoundly transformed the landscape of cancer therapy and...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: immune checkpoint inhibitors,­Immune related adverse events,­biomarkers,­Immunotherapy toxicity,­immune monitoring,­irAEs

Current Insights in Melanoma Immunology, Immune Escape and Immunotherapy Advances

Helen Gogas, Dimitrios Ziogas, Pedro Berraondo, Josep M. Piulats

Frontiers Media SA

Melanoma is a highly immunogenic tumor, characterized by the expression of multiple...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: melanoma microenvironment,­Immunologic biomarkers,­Immunotherapy,­Immunotherapy resistance,­immune checkpoint inhibitors,­Vaccines,­INT

Decoding Tumor Plasticity: Integrative Analysis of Epigenetic Regulation and Microenvironmental Adaptation

Haitao Wang, Guan-Jun Yang, Jian-Guo Zhou

Frontiers Media SA

Tumor plasticity presents a profound challenge in the field of oncology, signifying the...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: plasticity,­Epigenetic regulation,­cell fate,­Tumor Microenvironment,­transdifferentiation,­therapeutic resistance,­Malignant progression

Neuro-Immune Crosstalk in Peripheral Neuropathy: From Mechanisms to Therapeutic Opportunities

Xiao-Bo Wu, Xiaowei Chen, Bao-Chun Jiang, Bing Wang

Frontiers Media SA

Peripheral neuropathy encompasses a variety of conditions marked by damage or lesions to peripheral...

Health Immunology Multiple Sclerosis and Neuroimmunology

Keywords: peripheral neuropathy,­neuro-immune crosstalk,­Neuro-immune interactions,­Peripheral and Central nervous system,­Pathogenesis

The Role of Innate Immunity in the Pathogenesis of Autoimmune and Autoinflammatory Diseases

José Jiram Torres-Ruiz, José Luis Maravillas-Montero, Diana Gómez-Martín, Carmelo Carmona-Rivera

Frontiers Media SA

Myeloid cells have recently become more important in the pathogenesis of autoimmune and...

Health Immunology Autoimmune and Autoinflammatory Disorders

Keywords: innate immunity,­Autoimmunity,­Autoinflammation,­Myeloid Cells,­Pathogenesis