Neuro-Immune Interactions in Inflammation and Autoimmunity

Valentin A. Pavlov, Niccolo Terrando

Frontiers Media SA

The nervous system plays an important role in the regulation of immunity and inflammation. On the...

Health Immunology Inflammation

Keywords: Neuro-immune interactions,­Immunity,­Inflammation,­Autoimmunity,­Cytokines,­Antibodies

The second Life of Natural Killer (NK) Cells

Chiara Romagnani, Joseph C. Sun, Marco Colonna

Frontiers Media SA

Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of...

Health Immunology NK and Innate Lymphoid Cell Biology

Keywords: NK cells,­Natural Killer cells,­Immune Regulation,­Adaptive Immunity,­viral infection,­ILC,­Immunotherapy,­MHC-I,­Cancer,­immune therapy,­NK cell education

Epitope Discovery and Synthetic Vaccine Design

Clarisa Beatriz Palatnik-de-Sousa, Irene da Silva Soares, Daniela Santoro Rosa

Frontiers Media SA

Health Immunology Vaccines and Molecular Therapeutics

Keywords: epitope vaccines,­Synthetic vaccines,­T-cell epitopes,­B-Cell epitopes,­epitope prediction,­immunoinformatics,­in silico analysis,­multiepitope vaccines,­carbohydrate vaccines

Macromolecular Structure Underlying Recognition in Innate Immunity

Uttara SenGupta, Uday Kishore, Maha Ahmed Al-Mozaini

Frontiers Media SA

Health Immunology Molecular Innate Immunity

Keywords: pattern recognition,­innate immunity,­complement,­host–pathogen interactions,­protein–protein interaction,­HIV-1,­Malaria,­zebrafish model system

Radiation and the Immune System: Current Knowledge and Future Perspectives

Katalin Lumniczky, Serge M. Candéias, Udo S. Gaipl, Benjamin Frey

Frontiers Media SA

For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown,...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Ionizing radiation,­Radiotherapy,­Low dose radiation,­Immune System,­antitumor immune response,­Immunotherapy,­Inflammation,­intercellular communication,­radiotherapy-induced late effects,­Oxidative Stress

Tailoring NK Cell Receptor-Ligand Interactions: An Art in Evolution

Ulrike Koehl, Antoine Toubert, Gianfranco Pittari

Frontiers Media SA

Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is...

Health Immunology Alloimmunity and Transplantation

Keywords: Natural Killer cells,­Nk receptors,­Cancer,­Transplantation,­Immunotherapy,­Immune Evasion,­Checkpoint inhibitors,­chimeric antigen receptors,­bispecific antibodies

New Insights in Anaphylaxis

Vanesa Esteban, Carlos Pastor-Vargas

Frontiers Media SA

Anaphylaxis has usually been studied and understood from an immunological view and the main lethal...

Health Immunology Inflammation

Keywords: Anaphylaxis,­drug and food allergy,­molecular signaling,­augmentine factors,­Mast Cells,­Endothelial Cells

Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine

Paola Italiani, Diana Boraschi, Lucio R. C. Castellano, Paulo Bonan, Eliton S. Medeiros

Frontiers Media SA

The immune system has the double role of maintaining tissue integrity and homeostasis and of...

Health Immunology Inflammation

Keywords: nanomaterials,­innate immunity,­Inflammation,­complement,­Nanomedicine,­Immunomodulation,­immune system,­Vaccines,­anti-tumor therapy

HIV-Induced Damage of B Cells and Production of HIV Neutralizing Antibodies

Francesca Chiodi, Gabriella Scarlatti

Frontiers Media SA

Multiple dysfunctions take place in the B cell compartment during HIV-1 infection, comprising...

Health Immunology Viral Immunology

Keywords: B cells,­neutralizing and non neutralizing HIV-1 antibodies,­FcRL4,­HIV-1 vaccine targets,­BAFF,­clinical potential of HIV-1 antibodies,­mucosal IgA responses,­Gene Expression,­CXCL13,­maternal HIV antibodies,­auto-antibodies to CCR5