Novel Chimeric Antigen Receptor (CAR) Designs in engineering NK cells for Cancer

Wing Keung Chan, Youwei Wang, Nathan Denlinger

Frontiers Media SA

The development of novel Chimeric Antigen Receptor (CAR) has significantly transformed cancer...

Health Immunology NK and Innate Lymphoid Cell Biology

Keywords: Natural Killer cells,­Chimeric Antigen Receptor,­Solid tumor,­Tumor Microenvironment,­CAR-NK cells

Exploring the Immune-Metabolic Network in Diabetes

Beatrice Dufrusine, Damiana Pieragostino, Enrico Dainese

Frontiers Media SA

Diabetes, as defined by the World Health Organization, represents a collection of metabolic...

Health Immunology Cytokines and Soluble Mediators in Immunity

Keywords: type 1 diabetes,­type 2 diabetes,­Maturity-onset diabetes of the young (MODY),­Immune System,­Inflammation,­autoimmune disease,­diabetogenic cytokines,­Metabolism,­metabolic disorders,­metabolic syndrome,­Hyperglycemia

Innovative Insights into Pattern Recognition and Signaling in Innate Immunity

Francesca Granucci, Uday Kishore

Frontiers Media SA

The field of molecular innate immunity has witnessed remarkable progress, especially in the last...

Health Immunology Molecular Innate Immunity

Keywords: disease mechanism,­innate immunity,­pattern recognition,­signalling,­Therapeutic modulation,­Tissue microenvironment

Dissecting malaria protective immunity: acquired by natural infection and/or vaccination

Takafumi Tsuboi, Bernard Kanoi, Nirianne Querijero Palacpac, Wang Nguitragool

Frontiers Media SA

This Research Topic is the second volume of the Dissecting malaria protective immunity: acquired by...

Health Immunology Parasite Immunology

Keywords: Malaria,­Plasmodium vivax,­Vaccines,­Immunity,­mRNA

Targeting cancer-associated fibroblasts: Disrupting immune evasion and therapy resistance

Run Shi, Qiong Lu, Dunpeng Cai

Frontiers Media SA

The tumor microenvironment (TME) is a complex ecosystem comprising a variety of cell types,...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: cancer-associated fibroblasts,­Tumor microenvironment (TME),­immune cells,­Endothelial Cells

Deciphering Host-Virus Interactions and Advancing Therapeutics for Chronic Viral Infection

Qian Li, Jean-Pierre Routy, Hongzhou Lu

Frontiers Media SA

Chronic viral infections like HIV and HBV pose significant threats to human health, leading to...

Health Immunology Viral Immunology

Keywords: chronic viral infections,­HIV,­HBV,­T and B cells,­aids,­Chronic Hepatitis B {CHB),­virus-host immune interaction

Innovations in Development, Translational Research and Manufacturing of CAR T cells (2nd edition)

Michael Hudecek, Qasim Rafiq, Stephen Goldrick, Ulrike Koehl, Helene Negre

Frontiers Media SA

Immunotherapy with genetically engineered immune cell products is a transformative treatment...

Health Immunology Molecular Innate Immunity

Keywords: ATMPs,­CAR T cells,­TCR-transgenic T cells,­CAR NK cells,­gene transfer,­gene editing,­Automated manufacturing,­machine learning,­artificial intelligence,­Health Technology Assessment,­socioeconomic impact

Community Series in Engineered Immune Cells in Cancer Immunotherapy (EICCI), volume II

Cristina Maccalli, Francisco Martin, Axel Schambach

Frontiers Media SA

This Research Topic is the third volume of the “Engineered Immune Cells in Cancer Immunotherapy...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: adoptive cell therapy,­Chimeric Antigen Receptor,­cytokine release syndrome,­engineered T lymphocytes,­CAR-T cell therapy

Immunometabolism in Immunological Tolerance and Regulation: Novel Mechanisms and Clinical Interventions

Yali Zheng, Jingsong Mao, Yang Zhang, Hongwei Cheng

Frontiers Media SA

Immunometabolism, the study of how metabolic pathways interact with immune responses, is a critical...

Health Immunology Immunological Tolerance and Regulation

Keywords: immune microenvironment,­Immune Tolerance,­Immunometabolism,­Metabolic imaging,­metabolic reprogramming