Correlative light and volume electron microscopy: Methods and applications

Christopher Guerin, Feng-Xia Alice Liang, Saskia Lippens

Frontiers Media SA

Science Cell and Developmental Biology Cell Death and Survival

Keywords: correlative light and electron microscopy,­Volume electron microscopy,­serial block face scanning electron microscopy,­Focused Ion Beam Scanning Electron,­Microscopy,­array tomography,­image analysis

Integration of structural biology data in lead drug discovery and optimization

Marco Nardini, Pietro Roversi, Gianluca Molla

Frontiers Media SA

Science Molecular Biosciences Structural Biology

Keywords: Structural Biology,­Structural data,­Drug Discovery,­drug target,­optimization,­in silico,­screening,­high-throughput

Mechanisms, thermodynamics and kinetics of ligand binding revealed from molecular simulations and machine learning

Yinglong Miao, Weiliang Zhu, Chia-en A. Chang, J. Andrew McCammon

Frontiers Media SA

Science Molecular Biosciences Molecular Recognition

Keywords: ligand binding,­mechanisms,­pathways,­Thermodynamics,­free energies,­Kinetics,­Docking,­molecular dynamics,­Brownian dynamics,­machine learning

Solving the plasmalogen puzzle – from basic science to clinical application

Masanori Honsho, Fabian Dorninger, Johannes Berger

Frontiers Media SA

Science Molecular Biosciences Cellular Biochemistry

Keywords: Plasmalogens,­Rhizomelic chondrodysplasia punctata,­glycerolipids

Smart Nanomaterials for Biosensing and Therapy Applications

Qitong Huang, Miaomiao Yuan, Youbin Zheng, Zhe Wang, Ziqiang Xu

Frontiers Media SA

Science Bioengineering and Biotechnology Nanobiotechnology

Leveraging Machine Learning for Omics-driven Biomarker Discovery

Sheng Li, Charles Hsu, Tianyi Zhao, Liangcan He

Frontiers Media SA

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: omics,­biomarker,­machine learning,­big data,­translation

Ferroptosis in cancer and beyond

Yanqing Liu, Guo Chen, Chaoyun Pan, Xin Wang

Frontiers Media SA

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: ferroptosis,­Cancer,­Cell Death,­Oxidation,­p53

Small non-coding RNAs in diseases

Xiaoyong Bao, Yong Sun Lee, Inhan Lee

Frontiers Media SA

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: small non-coding RNAs,­SncRNAs,­tRNA derived RNA fragments,­tRFs,­tRF-based prognosis,­tRF-based diagnosis,­tRF-based therapies,­tissue-specific miRNAs,­viral-derived sncRNAs

Volume II: Novel molecular mechanisms and innovative therapeutic approaches for age-associated diseases

Leming Sun, Zhen Fan, Zhe-Sheng Chen

Frontiers Media SA

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: age-related diseases,­Molecular mechanisms,­target therapy,­Small molecular inhibitor,­Therapeutic biotechnology,­Molecular Pharmacology,­Functional Genomics