Cellular Contributors and Consequences of Protein Misfolding and Aggregation

Anoop Arunagiri, Emily Sontag, Verena Kohler, Arunkumar Venkatesan

Frontiers Media SA

Proper protein folding to its 3D structure is essential for cellular homeostasis. Protein...

Science Molecular Biosciences Cellular Biochemistry

Keywords: Protein Folding,­protein misfolding,­Aggregation,­Homeostasis,­Neurological Diseases

Emerging Trends in Cancer Research: Diagnostic and Therapeutic Breakthroughs

Valentyn Oksenych, Oleksandr Kamyshnyi, Rostyslav Bilyy, Peter Csaba Huszthy

Frontiers Media SA

Cancer remains one of the most challenging diseases to diagnose and treat, necessitating continual...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: Cancer biomarkers,­Molecular diagnostics,­targeted therapies,­Immunotherapy,­personalized medicine

New Insights into Oxidative Medicine: Unraveling the Complexity of Oxidative Stress in Health and Disease

Matteo Becatti, Claudia Fiorillo, Amir Alsharabasy

Frontiers Media SA

Given the success of

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: Antioxidants,­Aging,­Cancer,­Diet,­Inflammation,­Therapeutic interventions,­biomarkers,­Cardiovascular Diseases,­Neurodegenerative Diseases,­cellular signaling,­Mitochondrial dysfunction,­Oxidative damage,­redox biology,­redox status,­reactive oxygen species (ROS)

In Vitro Transcription (IVT) Reaction – The Gateway to New Therapeutic Modalities

Rok Sekirnik, Andreas Kuhn, Ana Margarida Azevedo, Zoltán Kis

Frontiers Media SA

The COVID-19 pandemic triggered an unprecedented rate of development of mRNA vaccines, and recently...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: IVT,­in vitro,­RNA,­mRNA,­tools,­methods

Cancer Biomarkers: Molecular Insights into Diagnosis, Prognosis, and Risk Prediction

Matteo Becatti, Shaoquan Zheng, Giuseppe Bronte

Frontiers Media SA

Given the success of

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: liquid biopsy,­Tumor Microenvironment,­Cancer biomarkers,­Molecular diagnostics,­Genomic biomarkers,­Proteomics,­single-cell sequencing,­Epigenomics,­circulating tumor DNA,­microRNA

The Role of Natural and Synthetic Antioxidants in the Therapeutic Targeting of Oxidative Stress

Alessia Remigante, Rossana Morabito, Valentina Mittova, Sara Spinelli

Frontiers Media SA

The field of oxidative stress and its role in the pathogenesis of various diseases has garnered...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: Antioxidants,­Oxidative Stress,­ROS,­therapeutic strategies,­Chronic Disease

Current Trends in Targeted and Non-Targeted Metabolomics in Analytical Toxicology

Geraldine M. Dowling, Markus R. Meyer

Frontiers Media SA

This article collection emphasizes the substantial potential and versatility of metabolomic...

Science Molecular Biosciences Metabolomics

Keywords: Metabolomics,­forensic,­clinical,­Therapeutic drug monitoring,­substance misuse,­Biomarkers Discovery,­machine learning,­biomarkers,­Ultra-high-performance liquid chromatography (UHPLC),­Gas chromatography–mass spectrometry (GC-MS),­ion mobility spectrometry,­Colistin-induced toxicity,­Therapeutic mechanism,­Metabolic pathways

Novel Biomarkers and Big Data-Based Biomedical Studies in Cancer Diagnosis and Management

Lin Zhang, Qingyu Luo

Frontiers Media SA

Cancer is a multifaceted disease that can elude the natural defense mechanisms of the immune...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: biomarkers,­Cancer,­Immunotherapy,­Inflammatory factors,­meta-analyses

Therapeutic Mechanism of Osteosarcoma

Yang Wang, Tong-Chuan He, Yang-Fan Lv

Frontiers Media SA

Osteosarcoma (OS) is the most common primary bone tumor, with a bimodal age distribution. The...

Science Molecular Biosciences Molecular Diagnostics and Therapeutics

Keywords: Osteosarcoma,­chemotherapy,­optical therapy,­Immunotherapy,­drug synergy,­targeted therapy,­Molecular mechanisms