Molecular Mechanisms and Targeted Therapies for Colorectal Cancer

Shilpa S. Dhar, Erika Ruiz-Garcia, Valeria Barresi, Oronzo Brunetti

Frontiers Media SA

Health Oncology Molecular and Cellular Oncology

Keywords: colorectal cancer,­molecular,­metastasis,­targeted therapies,­oncology

The Expanding Network of p53 Signaling: Reaching to the Unknown of Cancer

Xiang Zhou, Hua Lu, Ji Hoon Jung

Frontiers Media SA

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: p53,­non-coding RNA,­Metabolism,­cancer therapy,­Tumor Microenvironment

Molecules of the Extracellular Matrix as Cancer Targets

Nikos Karamanos, Martin Götte, Alberto Passi

Frontiers Media SA

Health Oncology Molecular and Cellular Oncology

Keywords: Extracellular Matrix,­cancer cell functions,­cell-matrix interactions,­Matrix receptors,­matrix macromolecules

Liquid Biopsy

Catherine Alix-Panabieres, George Calin, Klaus Pantel

Frontiers Media SA

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: circulating tumour cells (CTCs),­Circulating cell-free tumor DNA,­Exosomes,­microRNA,­tumour-educated platelets,­cancer diagnosis

The Role of Iron in Cancer Progression

Maryam Mehrpour, Ahmed Hamaï, Chang Gong

Frontiers Media SA

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: Iron,­iron metabolism,­cancer stem cells,­Ferritinophagy,­ferroptosis

Targeting the Wnt/ß-catenin Signaling Pathway in Cancer

Simone Patergnani, Donald Buchsbaum, Gary Piazza

Frontiers Media SA

Health Oncology Molecular and Cellular Oncology

Keywords: Wnt/β-catenin,­signaling,­targeted therpapy,­molecular targets,­Cancer

Tumor Microenvironment Signaling Networks in Pathophysiology and Therapeutics

Francesca Pirini, Paola Parrella, Daniele Vergara

Frontiers Media SA

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: Tumor Microenvironment,­signaling networks,­microbiota,­Cell Communication

Insights Into Cancer of Unknown Primary (CUP) Research: Novel Diagnostic and Therapeutic Strategies

Xichun Hu, Yi Ba, Xiaoyan Zhou, Natalie Cook, Qinghua Xu

Frontiers Media SA

Health Oncology Cancer Genetics

Keywords: Cancer of unknown primary (cup),­Immunochemistry (IHC),­Gene expression profiling (GEP),­Comprehensive genomic profiling (CGP),­precision medicine

Stress Response Signaling in Tumor Development and its Implications for Cancer Treatment

Shuyu Zhang, Feng He, Johan Bourghardt Fagman, Peng Zhao

Frontiers Media SA

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: Unfolded Protein Response,­oxidative stress response,­integrated stress response,­cancer prevention,­cancer therapy,­Cancer hallmarks