Metabolic Crosstalk between Cancer Cells and Immune Cells in the Tumor Microenvironment: Cellular and Molecular Insights, and their Therapeutic Implications

Parmanand Malvi, Balkrishna Chaube, Shivendra Vikram Singh

Frontiers Media SA

Metabolic reprogramming and immune evasion are critical hallmarks of cancer. The metabolic...

Health Oncology Cancer Metabolism

Keywords: Targeting metabolism,­Immunotherapy,­Tumor Microenvironment,­tumor immunology,­Immunometabolism,­immuno-oncology

Immune Checkpoints Regulatory Mechanisms and Immunotherapy Strategies in Gastrointestinal Tumors

Simona Gurzu, Rongxin Zhang, Qing Xi

Frontiers Media SA

Gastrointestinal cancers, including esophageal, stomach, colon, liver, and pancreatic cancer,...

Health Oncology Pharmacology of Anti-Cancer Drugs

Keywords: immune checkpoints,­PD-L1,­Immunotherapy,­Gastrointestinal cancers

Management of Rare Oncological Cases

Dragos Eugen Georgescu, Lidia Castagneto Gissey, Ferdinando Agresta, Mihai Teodor Georgescu

Frontiers Media SA

Rare oncological cases present a unique set of challenges for both patients and healthcare...

Health Oncology Cancer Epidemiology and Prevention

Keywords: Cancer,­rare,­Management,­Challenges,­Approaches,­Clinical experience,­diagnosis dilema,­novel therapies

Childhood Leukemias in Latin America: Epidemiology, Causality, Novel Predictive Profiles and Therapeutic Strategies

Juan Carlos Núñez-Enríquez, Juan Manuel Mejia-Arangure, Mario Ernesto Cruz-Munoz, Rosana Pelayo

Frontiers Media SA

Acute leukemias are the most frequent neoplasms in children and adolescents worldwide. In Latin...

Health Oncology Cancer Epidemiology and Prevention

Keywords: childhood leukemia,­Latinos,­Epidemiology,­Immune System,­therapeutic targets,­prognosis

Comprehensive Treatment Strategy for Improving Surgical Resection Rate of Retroperitoneal Sarcomas

Hanxing Tong, Ferdinando Carlo Maria Cananzi, Yong Zhang

Frontiers Media SA

Retroperitoneal sarcomas (RPS) account for 0.15% of all malignancies and approximately 15% of soft...

Health Oncology Surgical Oncology

Keywords: Sarcoma,­Soft Tissue Sarcoma,­Retroperitoneal sarcoma,­Surgery

Advances in Tumor Microenvironment, Immunology and Immunotherapy of Breast Cancer

Ying Lin, Shaoquan Zheng, Kosuke Kawaguchi, Jihong Cui

Frontiers Media SA

In recent years, many advances have emerged in immunological research and immunotherapy, including...

Health Oncology Breast Cancer

Keywords: breast cancer,­immunology,­Immunotherapy,­Tumor Microenvironment,­tumor infiltrating lymphocytes

Formation of Immunological Niches in Tumor Microenvironments: Mechanisms and Therapeutic Potential

Ying Luo, Weiling Li, Qingyu Luo, Xiaosheng Tan, Yabing Nan

Frontiers Media SA

The tumor microenvironment (TME) plays a pivotal role in cancer progression and response to...

Health Oncology Molecular and Cellular Oncology

Keywords: Tumor Microenvironment,­immunological niches,­Immune Evasion,­Immunotherapy,­Cytokines,­Chemokines,­Stromal Cells,­biomarkers,­therapeutic targets,­personalized medicine

Advanced Head and Neck Cancer: from Organ Preservation Strategies to extended resections and reconstruction

Vittorio Rampinelli, Francesco Missale, Filippo Marchi, Claudio Sampieri

Frontiers Media SA

Head and neck cancer represents a significant challenge in oncology due to its intricate anatomy,...

Health Oncology Head and Neck Cancer

Keywords: oral cancer,­Laryngeal cancer,­HPV related cancer,­sinonasal cancer,­Skin squamous cell carcinoma,­reconstructive surgery,­Microsurgery,­free flap,­bioendoscpy,­Immunotherapy,­videomics,­Radiomics,­Transoral,­Transnasal surgery,­Facial reanimation

Cancer Plasticity and The Microenvironment: Implications for Immunity and Therapy Response, volume II

Petranel Theresa Ferrao, Mohit Kumar Jolly, Anushka Dongre, Erik Thompson, Aparna Jayachandran, Sugandha Bhatia

Frontiers Media SA

The field of cancer research has been significantly impacted by the discovery of cellular...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: Cancer cell plasticity,­tumour microenvironment (TME),­Immunity,­Patient outcomes,­Epithelial-to-mesenchymal transition (EMT),­Adaptability,­treatment resistance,­Therapy response,­host factors,­Survival,­Tumour immune microenvironment (TIME)