Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views

Ignacio Pérez de Castro, Mar Carmena, Claude Prigent, David M. Glover

Frontiers Media SA

Aurora kinases are key mitotic regulators that have also been associated with tumor development and...

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: Aurora kinase,­Mitosis,­Meiosis,­antitumoral therapy,­Aurora inhibitors,­non-canonical roles

Exploring Cancer Metabolic Reprogramming through Molecular Imaging

Franca Podo, Zaver M. Bhujwalla, Egidio Iorio

Frontiers Media SA

The inclusion of oncogene-driven reprogramming of energy metabolism within the list of cancer...

Health Oncology Cancer Imaging and Diagnosis

Keywords: Cancer metabolic reprogramming,­Metabolism,­Molecular Imaging,­breast cancer,­ovarian cancer,­prostate cancer,­PET,­MRS,­functional MRI,­optical imaging

TAT 2017

Gustave Roussy Cancer Center, Congress by design

Frontiers Media SA

15th International Congress on Targeted Anticancer Therapies (TAT), 6-8 March 2017, Paris...

Health Oncology Cancer Therapies

Keywords: Targeted anticancer therapies,­oncology,­phase 1,­Drug Development,­cancer therapeutics,­early-phase

Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics

Christian R. Gomez

Frontiers Media SA

Hypoxic regions have been identified within tumors and its presence has been linked to malignant...

Science Cell and Developmental Biology Molecular and Cellular Oncology

Keywords: hypoxia,­tumor,­microenvironment,­HIF,­pH,­stress,­Stem Cells,­Leukemia,­biomarkers,­therapy

WIN 2016

Josep Tabernero, Stephen Friend, Christof von Kalle, Razelle Kurzrock, John Mendelsohn, Gordon B. Mills, Benjamin Neel, Thierry Philip, Richard L. Schilsky, Bin Tean Teh, Thomas Tursz, Vladimir Lazar, Catherine Bresson, Marinus Lobbezoo, Congress by Design

Frontiers Media SA

The WIN 2016 Symposium program will elaborate the overarching theme Innovative Approaches to...

Health Oncology Cancer Endocrinology

Plastic Surgery for the Oncological Patient

Adrien Daigeler, Björn Behr

Frontiers Media SA

The develoment of plastic surgery techniques allows for preserving and reconstruction of function...

Health Oncology Surgical Oncology

Keywords: plastic surgery,­free flap,­Pedicled flap,­skalp defect,­Breast reconstruction,­breast cancer,­Soft Tissue Sarcoma,­Soft tissue reconstruction

Human Tumor-Derived p53 Mutants: A Growing Family of Oncoproteins

Ygal Haupt, Giovanni Blandino

Frontiers Media SA

TP53 gene mutations are present in more than half of all human cancers. The resulting proteins are...

Health Oncology Molecular and Cellular Oncology

Keywords: mutant p53,­gain of function,­therapies,­mouse models,­Oncogenic addiction,­dominant netagive

Inhibiting PARP as a Strategic Target in Cancer

Christina Annunziata, Kristin Zorn

Frontiers Media SA

Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional...

Health Oncology Cancer Molecular Targets and Therapeutics

Keywords: PARP inhibitor,­Cancer,­DNA Damage,­DNA reapir,­Homologous Recombination,­combination therapy

14th International Congress on Targeted Anticancer Therapies (TAT 2016)

Giuseppe Giaccone, S. Gail Eckhardt, Lee M. Ellis, Marinus Lobbezoo, Cristiana Sessa, Jean-Charles Soria, Josep Tabernero, Louis M. Weiner

Frontiers Media SA

Targeted therapies, which include a range of monoclonal antibodies and small-molecule inhibitors,...

Health Oncology Cancer Endocrinology

Keywords: targeted therapies,­Drug Development,­Early clinical studies,­Innovative anticancer agents,­Drug Targets,­Translational research,­Immunological therapies