Targeting Neuroinflammation for Novel Therapeutics in Neurodegenerative Diseases

Pukar Khanal, Jatin Machhi, Rupesh V. Chikhale

Frontiers Media SA

Neurodegenerative disorders have increasing incidence with limited treatment options. Approaches to...

Science Pharmacology Ethnopharmacology

Keywords: Neurodegenerative Diseases,­Amyloid processing,­Autophagy,­Computational and Experimental Pharmacology,­Holistic treatment,­nootropics,­polypharmacology,­small molecules screening

Inflammation and Lipid Signaling in Disease Pathogenesis

Paola Patrignani, Angelo Sala, Bernhard Brüne, Dieter Steinhilber, Pietro Minuz

Frontiers Media SA

Inflammation plays a crucial role in the development of various diseases, including cancer,...

Science Pharmacology Inflammation Pharmacology

Keywords: Inflammation,­lipid signaling,­Disease pathogenesis,­chronic diseases,­Lipid Metabolism,­Inflammatory diseases,­lipidomics,­lipid mediators,­inflammatory responses,­Immune Regulation,­lipid biomarkers,­inflammatory pathways,­Immune responses

Plant and Fungal Extracts and Metabolites in Neurotherapy: Exploring Their Pharmacology and Potential Clinical Uses

Jian Hao, Igor Lavrov, Xianhu Zhou

Frontiers Media SA

Exploring phytochemistry and the treatment of neurological disorders, this research topic addresses...

Science Pharmacology Ethnopharmacology

Keywords: phytochemicals,­CNS Injury and Disease,­Mechanism,­Drug Discovery,­clinical translation

Interplay Between Chronic Pain and Affective-Cognitive Alterations: Shared Neural Mechanisms, Circuits, and Treatment

Luca Posa, Danilo De Gregorio, Serena Boccella, Kelly Smart

Frontiers Media SA

Pain is a multidimensional experience involving physical and negative emotional components....

Science Pharmacology Neuropharmacology

Keywords: Chronic Pain,­emotion,­Pain Perception,­Cognition,­affective pain processing

World No-Tobacco: Effects of Tobacco and Nicotine on the Brain

Massimo Grilli, Vijayapandi Pandy, Gilda Angela Neves, Graciela Noemí Balerio, Isis N. O. Souza

Frontiers Media SA

World No Tobacco Day, celebrated annually on May 31st, serves as a powerful global platform to...

Science Pharmacology Neuropharmacology

Keywords: #CollectionSeries,­tobacco exposure,­nicotine exposure,­nicotine addiction,­neurotoxic effects of tobacco,­Developing brain,­Cognition

The Mechanisms of Fibrotic Disorders and Pharmacological Therapies

Yaying Sun, Yanan Jiang, Wenyi Li

Frontiers Media SA

Fibrosis, characterized by uncontrolled extracellular matrix deposition, is a common phenomenon...

Science Pharmacology Inflammation Pharmacology

Keywords: Fibrosis,­targets,­Therapeutics,­fibroblast,­ferroptosis

Drug Discovery in Cancer Research: Success Stories and Open Challenges

Tashinga E. Bapiro, Wagdy Mohamed Eldehna, Viviana di Giacomo

Frontiers Media SA

In recent years, cancer drug development has witnessed significant advancements driven by...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: Drug Discovery,­Cancer,­targeted therapies,­Immunotherapy,­precision medicine,­Drug Resistance,­tumor heterogeneity

Advancements in the Heterogeneity of Sex for Tumors

Jianbin Bi, Prem Prakash Kushwaha, Gongbo Fu

Frontiers Media SA

Gender is widely acknowledged as a crucial determinant in the pathogenesis, progression, and...

Science Pharmacology Pharmacology of Anti-Cancer Drugs

Keywords: Sex specific tumor heterogeneity,­cancer biology,­tumor progression,­precision oncology,­therapeutic targets

Multisystem Inflammatory Syndrome observed Post-COVID-19: The Role of Natural Products, Medicinal Plants and Nutrients and the use of Prediction Tools Supporting Traditional Forms of Diagnosis

Anthony Booker, Ioannis Zabetakis, Nicole Elisabeth Teusch, Andrew Dalby, Thomas Hartung, Angela E. Peter

Frontiers Media SA

Beginning in December 2019, the world saw the rise and rapid spread of the COVID-19 disease, which...

Science Pharmacology Ethnopharmacology

Keywords: Multisystem inflammatory syndrome,­COVID-19,­Natural Products,­Medical plants,­nutrition,­Prediction tools,­Health Data Science