Natural Products and Their Derivatives in the Treatment of Inflammatory and Autoimmune Diseases

Jiao Xiao, Jian Chen, Mohamed El-Shazly

Frontiers Media SA

Inflammatory and autoimmune diseases are diseases of serious threat to human health and life. Over...

Health Immunology Nutritional Immunology

Keywords: Natural Products,­derivatives,­Treatment,­Inflammatory diseases,­Autoimmune Diseases

Enhancing T Cell Function: Innovations in Cancer Immunotherapy

Xuefeng Wang, Hong Jiang, Qian Sun, Valentyn Oksenych

Frontiers Media SA

Cancer immunotherapy has been revolutionized by targeting specific immune subsets within the tumor...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Tumor immune microenvironment,­t cell exhaustion,­stem-like CD8+ T cells,­Tumor-associated macrophages,­cancer immunotherapy

Exploring Macrophage Roles in Cancer Progression and Therapeutic Targeting

Yu Kato, George S. Karagiannis, David Entenberg

Frontiers Media SA

Macrophages are a pivotal component of the immune system, known for their versatility and essential...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: macrophage,­tumor initiation,­cancer metastasis,­cancer prevention,­Refractory cancer

Community Series in Novel Biomarkers in Tumor Immunity and Immunotherapy, volume II

Eyad Elkord, Takaji Matsutani

Frontiers Media SA

This Research Topic is the second volume of the “Novel Biomarkers in Tumor Immunity and...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Cancer,­biomarkers,­Immunotherapy,­targeted therapy,­Tumor Microenvironment

The Role of Ubiquitination in Disease Development, Progression, and Prognosis

Wenyi Jin, Mario Hiroyuki Hirata

Frontiers Media SA

Ubiquitination, an essential post-translational modification, controls various cellular functions...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Ubiquitination,­tumor cells,­Immune Regulation,­disease development,­disease progression,­Disease prognosis,­Tumor Microenvironment

Advancements and Cutting-Edge Approaches to Counteract the Inefficacy of Immune Checkpoint Inhibitor Therapies in Lung Cancer

Guangchun Han, Guangsheng Pei, Ziheng Wang

Frontiers Media SA

Lung cancer is among the cancers with the highest incidence in the world, of which about 80% of...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immune checkpoint inhibitor,­lung cancer,­programmed death receptor 1(PD-1),­programmed death ligand 1(PD-L1),­Tcell mucin immunoglobulin 3(TIM-3)

Crosstalk in Ferroptosis, Immunity & Inflammation

Qi Feng, Hua Zhong, Yu’e Liu

Frontiers Media SA

Ferroptosis represents a critical form of regulated cell death, notable for its reliance on iron...

Health Immunology Inflammation

Keywords: ferroptosis,­Inflammation,­Immunity,­Lipid Metabolism,­Inflammatory diseases,­Cancer,­Targeted drugs,­targeted drugs tumor immunosuppressive niche,­Immunotherapy,­chemotherapy

Unraveling the Molecular Mechanisms of Cytokine Signaling in Regulating Inflammatory Diseases

Wai Po Chong, Jian Zheng, Huawei Mao

Frontiers Media SA

Chronic and dysregulated inflammation play a significant role in the pathogenesis of autoimmune...

Health Immunology Cytokines and Soluble Mediators in Immunity

Keywords: Cytokin,­Inflammation,­Autoimmunity,­Infection - immunology,­signaling pathway

Epigenetics in the microbiome-host crosstalk: from mechanisms to Therapeutics

Chengfei Liu, Wenda Wu, Haoyu Liu, Hui-Xin Liu, Omar Ramos-Lopez

Frontiers Media SA

Epigenetic modifications allow cells to change gene expression without altering the genetic code,...

Health Immunology Microbial Immunology

Keywords: Dysbiosis,­epigenetic,­Bacteria,­microbiota