Exploring Macrophage Roles in Cancer Progression and Therapeutic Targeting

Yu Kato, George S. Karagiannis, David Entenberg

Frontiers Media SA

Macrophages are a pivotal component of the immune system, known for their versatility and essential...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: macrophage,­tumor initiation,­cancer metastasis,­cancer prevention,­Refractory cancer

Community Series in Novel Biomarkers in Tumor Immunity and Immunotherapy, volume II

Eyad Elkord, Takaji Matsutani

Frontiers Media SA

This Research Topic is the second volume of the “Novel Biomarkers in Tumor Immunity and...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Cancer,­biomarkers,­Immunotherapy,­targeted therapy,­Tumor Microenvironment

The Role of Ubiquitination in Disease Development, Progression, and Prognosis

Wenyi Jin, Mario Hiroyuki Hirata

Frontiers Media SA

Ubiquitination, an essential post-translational modification, controls various cellular functions...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Ubiquitination,­tumor cells,­Immune Regulation,­disease development,­disease progression,­Disease prognosis,­Tumor Microenvironment

Advancements and Cutting-Edge Approaches to Counteract the Inefficacy of Immune Checkpoint Inhibitor Therapies in Lung Cancer

Guangchun Han, Guangsheng Pei, Ziheng Wang

Frontiers Media SA

Lung cancer is among the cancers with the highest incidence in the world, of which about 80% of...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immune checkpoint inhibitor,­lung cancer,­programmed death receptor 1(PD-1),­programmed death ligand 1(PD-L1),­Tcell mucin immunoglobulin 3(TIM-3)

Exploring Oncolytic Virotherapy in Solid Tumor Treatment

Peng Qu, Guohao Wang, Yue Huang

Frontiers Media SA

Oncolytic virus therapy for solid tumor is an well-established concept as a promising tumor...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: oncolytic virus,­therapy,­Solid tumor,­combination therapeutics,­immune cells,­delivery system,­Engineered virus

Unveiling Biomarkers and Mechanisms in the Tumor-Immune Nexus

Wantao Wu, Pengpeng Zhang, Jiaheng Xie, Uday Kishore

Frontiers Media SA

The interplay between cancer cells and the immune system is a critical area of research, with...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy Response Biomarkers,­Tumor-immune interactions,­Immune evasion mechanisms,­Tumor Microenvironment,­Next-generation sequencing technologies,­single-cell RNA sequencing,­cancer immunology,­Therapeutic Targets in Immunotherapy

Immunological Precision Therapeutics: Integrating Multi-Omics Technologies and Comprehensive Approaches for Personalized Immune Intervention

Wenyi Jin, Raquel Alarcon Rodriguez, Mar Requena Mullor

Frontiers Media SA

In the realm of modern immunology, the pursuit of precision therapeutics has emerged as a paramount...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy,­precision medicine,­Multi-omics analysis,­immune signatures,­personalized therapy

Circadian Rhythms and Cancer Hallmarks: Toward Advances in Immune-Based Therapeutics, and Outcomes

Elizabeth Cash, Sandra E. Sephton, Pasquale F. Innominato

Frontiers Media SA

Circadian rhythms are the daily fluctuations in physiological processes that govern cell cycles and...

Health Oncology Cancer Immunity and Immunotherapy

Keywords: circadian,­Cancer,­immuno-oncology,­clock gene,­Cancer hallmarks,­Chronotherapy,­cancer therapeutics

Beyond PD-1: novel checkpoint receptors and ligands as targets for immunotherapy

Jesse Haramati, Dallas Flies, Fabiola Solorzano Ibarra

Frontiers Media SA

The incredible power of the immune system to control or eliminate neoplasias has been made evident...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: combined checkpoint therapies,­ICI,­engagers,­redirecting T cells,­biomarkers,­CAR,­Innate,­NK,­agonist,­Inflammation,­Phagocytosis