Achilles Heel of CAR T-Cell Therapy

Maurizio Chiriva-Internati, Fabio Grizzi

Frontiers Media SA

Chimeric Antigen Receptor (CAR) T-cell therapy represents a groundbreaking advancement in cancer...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: CAR-T therapy,­biomarker,­ag,­ab,­target,­Allogeneic,­autologous,­cell therapy,­virus,­innate and adoptive cell therapy

Community Series in The Immunosuppressive Tumor Microenvironment and Strategies to Revert its Immune Regulatory Milieu for Cancer Immunotherapy, volume II

Jayakumar Nair, Mazdak Ganjalikhani Hakemi

Frontiers Media SA

This Research Topic is the second volume of the “The Immunosuppressive Tumor Microenvironment and...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Tumor Microenvironment,­Tumor immunotherapy,­immunosurveillance,­Immunometabolism,­Immunosuppressive cells,­Tumor spheroids,­tumor organoids,­Multiorgan-on-chip,­organ-on-chip,­Microfluidic chips

New Avenues for the Development of Advanced Immunotherapies: Capitalizing on Studies of the B and T Cell Receptor Repertoire

Massimiliano Mazza, Fabio Nicolini, Maria Del Mar Naranjo Gomez, Mireia Pelegrin

Frontiers Media SA

Immunotherapy has emerged as a transformative domain within oncology and a variety of other medical...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Antibody identification and engineering,­Immunotherapy,­bi-specific antibodies,­CAR-T cells,­TCR/ BCR repertoire study

Response/Resistance to PD-1 Axis Inhibitors: Focus on the Tumor Microenvironment

Thazin N. Aung, Ioannis Vathiotis, Arutha Kulasinghe

Frontiers Media SA

PD-1 axis inhibitors are a group of immune checkpoint inhibitors (ICIs) that block the PD-1/PD-L1...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: PD-1 inhibitor,­Tumor Microenvironment,­Immunotherapy response,­resistance to PD-1 inhibitor,­PD-1/PD-L1 blockade,­cancer immunotherapy,­T cells,­NK cells,­Immunotherapy resistance

Community Series in Immune Responses Against Tumors - From the Bench to the Bedside, volume II

Tiezheng Hou, Xiaoxiao Liu, Chunjing Wang, Shisan Bao

Frontiers Media SA

This Research Topic is the second volume of the “Immune Responses Against Tumors - From the Bench...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: amino acid metabolism,­machine learning,­Clonal neoantigen,­adoptive cell therapy,­Targeted nanoparticle

The crosstalk between emerging cell death and immune microenvironment remodeling in cancer progression and treatment

Bufu Tang, Xuanzhang Huang, Weiliang Hou, Ling Wang, Jifeng Wang

Frontiers Media SA

The field of cancer research has increasingly focused on the intricate interplay between regulated...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Emerging cell death,­immune microenvironment remodeling,­RCD,­Regulated cell death,­Curroptosis,­ferroptosis,­Pan-apoptosis

Precision Immunotherapy and Novel Target Discovery in Hematological Malignancy

Beibei Zhang, Tuoen Liu, Yu Pan

Frontiers Media SA

Hematological malignancies represent defying clinical conditions affecting either the lymphoid or...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Immunotherapy,­neoantigen,­target,­hematological malignancy,­precision medicine

Nanoparticles for Cancer Immunotherapy: from Basics to Clinics

Fernando Torres Andón, Clément Anfray, Paola Allavena, Maria J. Oliveira

Frontiers Media SA

Antitumoral immunotherapies have achieved remarkable results in the treatment of a variety of...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Nanoparticles,­cancer immunotherapy,­Tumor Microenvironment,­Drug delivery,­Cancer Vaccines,­innate immunity,­combination therapy,­Cancer resistance,­Cell immunotherapy,­theragnostic nanomedicine

Exploring the Intersection of Cancer Metabolism, Metastasis and Immunotherapy

Lei Huang, Pengpeng Liu

Frontiers Media SA

Cancer metabolism is a critical area of research, central to understanding how malignant tumors...

Health Immunology Cancer Immunity and Immunotherapy

Keywords: Cancer Metabolism,­metabolic reprogramming,­Tumor Microenvironment,­immunotheraphy,­mestasis