AUTHOR=Tang Xinhui , Yv Hui , Wang Fei , Wang Jiahan , Liu Siyv , Wu Xiaoyue , Dong Rui , Lin Xu , Wang Bin , Bi Yanlin 

TITLE=The Relationship Between Suboptimal Social Networks and Postoperative Delirium: The PNDABLE Study

JOURNAL=Frontiers in Aging Neuroscience

VOLUME=Volume 14 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2022.851368

DOI=10.3389/fnagi.2022.851368

ISSN=1663-4365

ABSTRACT=We investigated whether social networks are a risk factor for POD, and to verify whether different levels of intimacy in the same social relationship can affect the concentration of cerebrospinal fluid (CSF) biomarkers, such as amyloid-β(Aβ42), total tau(T-tau) and phosphorylated tau(P-tau), and the mediating role of CSF biomarkers between social network and POD in middle-aged and elderly Han people.