AUTHOR=Chaudhary Shefali , Zhang Sheng , Chen Yu , Dominguez Jacqueline C. , Chao Herta H. , Li Chiang-Shan R. TITLE=Age-related reduction in anxiety and neural encoding of negative emotional memory JOURNAL=Frontiers in Aging Neuroscience VOLUME=Volume 16 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2024.1375435 DOI=10.3389/fnagi.2024.1375435 ISSN=1663-4365 ABSTRACT=Author Contribution: SC collected data, performed analysis, and drafted the manuscript. SZ and YC assisted in data analysis. HHC and CRL were responsible for the study concept and design.HHC, CRL and JCD provided critical revision of the manuscript. All authors critically reviewed the content and approved the final version for publication.The data associated with this work is available at (osf.io/qa8sn).School of Medicine approved the study procedures. All participants signed an informed consent prior to the study.A supplementary material is associated with this manuscript. The supplement describes the mediation analysis methodology, which follows from our previously published study cited in the manuscript. Additionally, the supplement presents the statistics of all tested mediation models, with the significant ones highlighted in the manuscript.