AUTHOR=Zhou Xuerong , Liu Zhifan , Bai Guiqin , Dazhang Bai , Zhao Peilin , Wang Xiaoming , Jiang Guohui 

TITLE=Bioinformatics analysis of the potential receptor and therapeutic drugs for Alzheimer’s disease with comorbid Parkinson’s disease

JOURNAL=Frontiers in Aging Neuroscience

VOLUME=Volume 16 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/aging-neuroscience/articles/10.3389/fnagi.2024.1411320

DOI=10.3389/fnagi.2024.1411320

ISSN=1663-4365

ABSTRACT=• Epidermal growth factor receptor (EGFR) was identified as a potential crucial receptor gene in Alzheimer's disease (AD) and Parkinson's disease (PD) comorbidity via bioinformatics analysis.• Semagacestat was identified as a drug candidate for AD combined with PD through gene set enrichment analysis.• Molecular docking revealed that there is a high binding affinity between semagacestat and EGFR.批注 [E31]: Please define. Abbreviations and acronyms are often defined the first time they are used within the abstract and again in the main text and then used throughout the remainder of the manuscript. Please consider adhering to this convention for all abbreviations throughout the manuscript.