AUTHOR=Cao Wei 

TITLE=IFN-Aging: Coupling Aging With Interferon Response

JOURNAL=Frontiers in Aging

VOLUME=Volume 3 - 2022

YEAR=2022

URL=https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2022.870489

DOI=10.3389/fragi.2022.870489

ISSN=2673-6217

ABSTRACT=Chronic inflammation affects many diseases and conditions, including aging. Interferons are a part of the immune defense against viral infections. Paradoxically, various aging tissues and organs from mammalian hosts perpetually accumulate changes brought by interferon pathway activation. Here I connote the mechanisms behind this phenomenon and discuss its implications in age-related pathology.