https://www.frontiersin.org/journals/aging RSS Feed for Frontiers in Aging | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-04-21T01:41:57.894+00:00 60 https://www.frontiersin.org/articles/10.3389/fragi.2026.1642652 https://www.frontiersin.org/articles/10.3389/fragi.2026.1642652 2026-04-20T00:00:00Z Review Doris Cardona-ArangoValeria Santacruz-RestrepoAlejandra Rendón-MontoyaJuliana Madrigal-CadavidAlejandra Segura-CardonaJorge Iván Estrada-Acevedo https://www.frontiersin.org/articles/10.3389/fragi.2026.1769377 https://www.frontiersin.org/articles/10.3389/fragi.2026.1769377 2026-04-20T00:00:00Z Mini Review Timothy A. DonlonUlrich Müller https://www.frontiersin.org/articles/10.3389/fragi.2026.1805909 https://www.frontiersin.org/articles/10.3389/fragi.2026.1805909 2026-04-17T00:00:00Z Original Research Allison MarzilianoNicholas R. EatonMahdia ParkerMaged GhalyDiana SchettiniMaureen BalramCarla PerissinottoMichael A. Diefenbach https://www.frontiersin.org/articles/10.3389/fragi.2026.1812899 https://www.frontiersin.org/articles/10.3389/fragi.2026.1812899 2026-04-17T00:00:00Z Original Research Kerri Winters-StoneSydnee A. StoylesNathan DieckmannAlexandra O. SokolovaJulie N. GraffArthur HungShirlene WangKaren S. Lyons 1 indicated at least some loneliness and we ran correlations between CL and measures of social, physical and mental health. Within PC couples we explored the potential benefits of different types of dyadic exercise programs (supervised, group partnered exercise, supervised separate groups of survivors or partners, or unsupervised independent exercise) on CL over 6 months.Results96% of breast cancer survivors (BCS) and 77% of prostate cancer survivors (PCS) reported CL at baseline. CL was positively associated with anxiety (rho = 0.44, 0.77), depressive symptoms (rho = 0.60, 0.67) and pain (rho = 0.34, 0.23) and inversely associated with social functioning (rho = −0.54, −0.55) among BCS and PCS, respectively (all p < 0.01). CL was inversely associated with physical functioning in BCS (rho = −0.35), but not PCS. Among care partners, 74%–77% of care partners for each BCS and PCS reported CL related to their partner’s cancer at baseline. CL was positively associated with anxiety (rho = 0.43, 0.30) and depressive symptoms (rho = 0.62, 0.45) among BC and PC care partners, respectively (all p < 0.01). CL was inversely associated with social functioning in BC partners only (rho = −0.45, p < 0.01), but not with physical functioning in either group. Within PC couples, there was a significant (inverse) interaction between change in CL over six-months of exercise and baseline loneliness. Declines in CL for both PCS and care partners were steepest in the exercise program where they trained with other PCS or care partners.ConclusionRelationships may not offer enough social support to avoid feelings of loneliness associated with cancer that in turn affects the physical, emotional and social health of each partner. However, exercise may help rebuild connection within the couple and be an avenue for informal social support that together could reduce loneliness.Clinical Trial Registration[clinicaltrials.gov]: identifier, [NCT03630354].]]> https://www.frontiersin.org/articles/10.3389/fragi.2026.1816647 https://www.frontiersin.org/articles/10.3389/fragi.2026.1816647 2026-04-15T00:00:00Z Review Elma van GarderenMandy VisserWilco P. Achterberg https://www.frontiersin.org/articles/10.3389/fragi.2026.1741360 https://www.frontiersin.org/articles/10.3389/fragi.2026.1741360 2026-04-15T00:00:00Z Original Research Yumei XuLiang ZhangTianci LiYanqiu ZhaoShuo WangJunwen QiLinsen Shi https://www.frontiersin.org/articles/10.3389/fragi.2026.1780401 https://www.frontiersin.org/articles/10.3389/fragi.2026.1780401 2026-04-14T00:00:00Z Original Research Min WangJingli YuQinshan HuangShuxun ChiLuping Qu https://www.frontiersin.org/articles/10.3389/fragi.2026.1725187 https://www.frontiersin.org/articles/10.3389/fragi.2026.1725187 2026-04-10T00:00:00Z Original Research Yingqi YuChaoxuan WangRuirui WangYifang ChenZeren WeiYanan XiaoUlf ElbeltAnne PietznerKarsten H. Weylandt https://www.frontiersin.org/articles/10.3389/fragi.2026.1794896 https://www.frontiersin.org/articles/10.3389/fragi.2026.1794896 2026-04-09T00:00:00Z Original Research Renan F. do Espírito-SantoYouping ZhangJin Y. RoJoyce T. Da Silva https://www.frontiersin.org/articles/10.3389/fragi.2026.1780462 https://www.frontiersin.org/articles/10.3389/fragi.2026.1780462 2026-04-09T00:00:00Z Review Zuzhou WenYun YeJunzhao QiaoHongqiang Chen https://www.frontiersin.org/articles/10.3389/fragi.2026.1794820 https://www.frontiersin.org/articles/10.3389/fragi.2026.1794820 2026-04-08T00:00:00Z Review Yan HanGaomei LuoYanhao HuangZhicheng CaiWei SuXuejun KuangLijuan HuangLi WeiFenghuang MingZiqi HeZimeng YangJingqi WangWei JiangChanchan XiaoQingbing HuJianhui Yan https://www.frontiersin.org/articles/10.3389/fragi.2026.1652951 https://www.frontiersin.org/articles/10.3389/fragi.2026.1652951 2026-04-08T00:00:00Z Original Research Fuguo YangYuanchao LuoKang ChenRenjian He 0.05), with no significant differences in re-fracture (11.94% vs. 15.28%) or anti-osteoporosis compliance (28.36% vs. 33.33%). Subgroup analysis revealed that PCKP provided more symmetric cement distribution (p = 0.02) and a 21% lower leakage risk in moderate-to-severe OVCFs (Genant 2–3).ConclusionPCKP enhances early biomechanical stability in moderate-to-severe OVCFs through optimized cement dispersion, while long-term efficacy relies on standardized anti-osteoporosis therapy. A stepwise decision model (“PCKP for Genant 2–3, UPKP for mild cases”), combined with a “vertebral augmentation–bone metabolism modulation–behavioral intervention” strategy, is recommended.]]> https://www.frontiersin.org/articles/10.3389/fragi.2026.1790247 https://www.frontiersin.org/articles/10.3389/fragi.2026.1790247 2026-04-07T00:00:00Z Mini Review Volodymyr MavrychInna ShypilovaOlena Bolgova https://www.frontiersin.org/articles/10.3389/fragi.2026.1695517 https://www.frontiersin.org/articles/10.3389/fragi.2026.1695517 2026-04-02T00:00:00Z Original Research Florian LegrandIoannis BargiotasMatthieu Ndumbi LukuenyaJean-Marc EycheneEvelyne AlastorLise HaddoukChristophe LabourdetteSébastien LerusteJean-Marc FrancoFrédéric SandronPierre-Paul Vidal https://www.frontiersin.org/articles/10.3389/fragi.2026.1799545 https://www.frontiersin.org/articles/10.3389/fragi.2026.1799545 2026-04-02T00:00:00Z Mini Review Thomas V. MerluzziAndrea ChiricoTommaso PalombiErrol J. Philip https://www.frontiersin.org/articles/10.3389/fragi.2026.1838683 https://www.frontiersin.org/articles/10.3389/fragi.2026.1838683 2026-04-01T00:00:00Z Correction Ling Yin https://www.frontiersin.org/articles/10.3389/fragi.2026.1805053 https://www.frontiersin.org/articles/10.3389/fragi.2026.1805053 2026-03-31T00:00:00Z Original Research Sara Cruces-SalgueroIgor LarrañagaJavier MarAnder Matheu https://www.frontiersin.org/articles/10.3389/fragi.2026.1736517 https://www.frontiersin.org/articles/10.3389/fragi.2026.1736517 2026-03-30T00:00:00Z Original Research Konstantin WarnekeAndreas StotzAndreas KonradAstrid Zech https://www.frontiersin.org/articles/10.3389/fragi.2026.1771908 https://www.frontiersin.org/articles/10.3389/fragi.2026.1771908 2026-03-27T00:00:00Z Original Research Liliana Andrea López MorenoCarlos Moreno PascualMaría Consuelo Sancho SánchezAlejandro Moreno-Mateos https://www.frontiersin.org/articles/10.3389/fragi.2026.1726714 https://www.frontiersin.org/articles/10.3389/fragi.2026.1726714 2026-03-26T00:00:00Z Original Research Dezhao JiaMing WangHong YuYongzhi ZhangYi WangYiming SunMengfei Wu