Frontiers in Aging | Musculoskeletal Aging section | New and Recent Articles https://www.frontiersin.org/journals/aging/sections/musculoskeletal-aging RSS Feed for Musculoskeletal Aging section in the Frontiers in Aging journal | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-14T20:18:21.811+00:00 60 https://www.frontiersin.org/articles/10.3389/fragi.2026.1859857 https://www.frontiersin.org/articles/10.3389/fragi.2026.1859857 <![CDATA[Editorial: Enhancing geriatric care with AI: strategies for fall prevention and aging-in-place]]> 2026-05-01T00:00:00Z Editorial Siu Shing ManRonggang ZhouLu PengAlan Hoi Shou Chan https://www.frontiersin.org/articles/10.3389/fragi.2026.1855184 https://www.frontiersin.org/articles/10.3389/fragi.2026.1855184 <![CDATA[Editorial: Women at the forefront of musculoskeletal aging science]]> 2026-04-30T00:00:00Z Editorial Caglar CosardereliogluStefania ToselliLigiana Pires Corona https://www.frontiersin.org/articles/10.3389/fragi.2026.1816647 https://www.frontiersin.org/articles/10.3389/fragi.2026.1816647 <![CDATA[Physical activity interventions to improve physical function in temporarily non-ambulant older persons: a scoping review]]> 2026-04-15T00:00:00Z Review Elma van GarderenMandy VisserWilco P. Achterberg https://www.frontiersin.org/articles/10.3389/fragi.2026.1780462 https://www.frontiersin.org/articles/10.3389/fragi.2026.1780462 <![CDATA[The interplay between stroke and hip fractures: a narrative review of mechanisms, risk assessment, and prevention]]> 2026-04-09T00:00:00Z Review Zuzhou WenYun YeJunzhao QiaoHongqiang Chen https://www.frontiersin.org/articles/10.3389/fragi.2026.1652951 https://www.frontiersin.org/articles/10.3389/fragi.2026.1652951 <![CDATA[PCKP versus UPKP for moderate-to-severe osteoporotic vertebral compression fractures: a prospective randomized controlled trial revealing synergistic mechanisms of optimized bone cement distribution and anti-osteoporosis therapy on medium-to-long-term outcomes]]> 2026-04-08T00:00:00Z Original Research Fuguo YangYuanchao LuoKang ChenRenjian He 0.05), with no significant differences in re-fracture (11.94% vs. 15.28%) or anti-osteoporosis compliance (28.36% vs. 33.33%). Subgroup analysis revealed that PCKP provided more symmetric cement distribution (p = 0.02) and a 21% lower leakage risk in moderate-to-severe OVCFs (Genant 2–3).ConclusionPCKP enhances early biomechanical stability in moderate-to-severe OVCFs through optimized cement dispersion, while long-term efficacy relies on standardized anti-osteoporosis therapy. A stepwise decision model (“PCKP for Genant 2–3, UPKP for mild cases”), combined with a “vertebral augmentation–bone metabolism modulation–behavioral intervention” strategy, is recommended.]]> https://www.frontiersin.org/articles/10.3389/fragi.2026.1695517 https://www.frontiersin.org/articles/10.3389/fragi.2026.1695517 <![CDATA[Multimodal frailty detection in primary care using a portable sensor-based platform: exploratory results]]> 2026-04-02T00:00:00Z Original Research Florian LegrandIoannis BargiotasMatthieu Ndumbi LukuenyaJean-Marc EycheneEvelyne AlastorLise HaddoukChristophe LabourdetteSébastien LerusteJean-Marc FrancoFrédéric SandronPierre-Paul Vidal https://www.frontiersin.org/articles/10.3389/fragi.2026.1736517 https://www.frontiersin.org/articles/10.3389/fragi.2026.1736517 <![CDATA[Association between maximal lower leg strength and static and dynamic balance as well as gait velocity in older adults]]> 2026-03-30T00:00:00Z Original Research Konstantin WarnekeAndreas StotzAndreas KonradAstrid Zech https://www.frontiersin.org/articles/10.3389/fragi.2026.1726714 https://www.frontiersin.org/articles/10.3389/fragi.2026.1726714 <![CDATA[Comprehensive quantitative analysis of muscle cross-sectional area and intramuscular fat infiltration of hip using modified DIXON MRI based on chemical shift encoding technique]]> 2026-03-26T00:00:00Z Original Research Dezhao JiaMing WangHong YuYongzhi ZhangYi WangYiming SunMengfei Wu https://www.frontiersin.org/articles/10.3389/fragi.2026.1750450 https://www.frontiersin.org/articles/10.3389/fragi.2026.1750450 <![CDATA[Targeting innate immunity to modulate bone metabolism: a novel strategy for osteoporosis treatment]]> 2026-03-20T00:00:00Z Review Wenjie KouXiaomin LuZhe ZhangKaiwen LiuZhihuan LiuBin JiangHongping WangJishu LiHu LuChenglong GuoLinzhong CaoXiaogang Zhang https://www.frontiersin.org/articles/10.3389/fragi.2026.1736916 https://www.frontiersin.org/articles/10.3389/fragi.2026.1736916 <![CDATA[Metabolite biomarkers present in urine predict alterations in skeletal muscle associated with sarcopenia]]> 2026-03-20T00:00:00Z Original Research Rafaela Andrade-VieiraHirad A. FeridooniAlyne TeixeiraDylan Deska-GauthierXingjian ChangTobias KarakachRebecca MoyerJohn P. Frampton https://www.frontiersin.org/articles/10.3389/fragi.2026.1715723 https://www.frontiersin.org/articles/10.3389/fragi.2026.1715723 <![CDATA[Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation]]> 2026-03-18T00:00:00Z Original Research Robin MathieuFlorian ChambellantDenis BarbusseElizabeth ThomasCharalambos PapaxanthisPauline M. HiltPatrick ManckoundiaFrance MoureyJeremie Gaveau https://www.frontiersin.org/articles/10.3389/fragi.2026.1823512 https://www.frontiersin.org/articles/10.3389/fragi.2026.1823512 <![CDATA[Correction: Muscle quality correlates with hearing thresholds: a cross-sectional analysis]]> 2026-03-18T00:00:00Z Correction Young-Jee JeonJi Ho LeeByung Chul KangJoong Keun Kwon https://www.frontiersin.org/articles/10.3389/fragi.2026.1736263 https://www.frontiersin.org/articles/10.3389/fragi.2026.1736263 <![CDATA[Ginsenoside Rg1 antagonizes diabetic osteoporosis by regulating ferroptosis via mitochondrial membrane potential in H-type vascular endothelial cells]]> 2026-03-17T00:00:00Z Original Research Mi ChenHongxiang ZhengRui BaiYingjie HuangGuoyu PangHaixia ZhuZhuoxin YiWenhui Chen https://www.frontiersin.org/articles/10.3389/fragi.2026.1768566 https://www.frontiersin.org/articles/10.3389/fragi.2026.1768566 <![CDATA[Wnt16: a new potential therapeutic target for osteoporotic non-vertebral fracture treatment]]> 2026-03-09T00:00:00Z Review Chen TianpengXia QishuiYang FoWu MingjunHu HaiboJin JiuchuShi XiaolinJiang Gongtao https://www.frontiersin.org/articles/10.3389/fragi.2026.1649622 https://www.frontiersin.org/articles/10.3389/fragi.2026.1649622 <![CDATA[SARC-T a new physical test for sarcopenia assessment with development, validation and physiological evaluation]]> 2026-03-02T00:00:00Z Original Research Blanca Pedauyé-RuedaJosé Luis Maté-MuñozJuan Hernández-LougedoIñigo Aparicio-GarcíaSara Cerrolaza-TudancaManuel Rozalén-BustínInmaculada Rodríguez-MorenoPablo García-Fernández https://www.frontiersin.org/articles/10.3389/fragi.2026.1712785 https://www.frontiersin.org/articles/10.3389/fragi.2026.1712785 <![CDATA[Evaluating the performance of large language models in sarcopenia-related patient queries: a foundational assessment for patient-centered validation]]> 2026-02-27T00:00:00Z Original Research Tao HuangBen KirkJacqueline CloseJae-young LimGustavo DuquePeter EbelingMinghui YangMaoyi TianChun Sing ChuiChaoran LiuNing ZhangWing-Hoi CheungRonald Man Yeung Wong 0.05).ConclusionDespite minor differences in performance across domains, all three LLMs demonstrated acceptable accuracy and comprehensiveness when responding to sarcopenia-related queries. Their comparable results may reflect similarly recent training data and language capabilities. These findings suggest that LLMs could potentially serve as a valuable tool in patient education and care on sarcopenia. This study provides an initial, expert-based assessment of LLM information quality regarding sarcopenia. While the responses demonstrated good accuracy, this evaluation focuses on content correctness from a clinical perspective. Future research must complement these findings by directly engaging older adult cohorts before clinical implementation can be considered. However, human oversight remains essential to ensure safe and appropriate assessment and individually tailored advice and management.]]> https://www.frontiersin.org/articles/10.3389/fragi.2026.1772792 https://www.frontiersin.org/articles/10.3389/fragi.2026.1772792 <![CDATA[Development and validation of a machine learning-based risk prediction model for sarcopenia in community hospital patients: a retrospective cohort study]]> 2026-02-26T00:00:00Z Original Research Xue ZhaoWang YaoJiawei ShenXinyu TangJue ZhengChang GuoSun YeMiqiong LiChao WangPeihao Yin https://www.frontiersin.org/articles/10.3389/fragi.2026.1736069 https://www.frontiersin.org/articles/10.3389/fragi.2026.1736069 <![CDATA[Elevated circulating GDF11 and its role in age-related sarcopenia: insights from clinical, transcriptomic, and in vitro analyses]]> 2026-02-25T00:00:00Z Original Research Rui ChenXin DaiHong WangTing ZhangZhao ZhangYaoxia LiuZhen Fan https://www.frontiersin.org/articles/10.3389/fragi.2026.1765052 https://www.frontiersin.org/articles/10.3389/fragi.2026.1765052 <![CDATA[Obesity and low lean mass are associated with dysregulated IGFBP-3, inflammatory biomarkers, and physical impairment in older adult women with frailty]]> 2026-02-18T00:00:00Z Brief Research Report Alan L. FernandesRosa M. R. PereiraValeria F. CaparboCamila S. FigueredoCaroline F. GomesEduardo F. B. NetoDiogo S. Domiciano https://www.frontiersin.org/articles/10.3389/fragi.2026.1748066 https://www.frontiersin.org/articles/10.3389/fragi.2026.1748066 <![CDATA[Impact of comorbidities in patients with erosive hand osteoarthritis (EHOA), a monocentric study]]> 2026-02-12T00:00:00Z Brief Research Report S. BindoliG. CozziC. BenvolutiM. LorenzinS. VioP. SfrisoM. FaveroR. Ramonda