AUTHOR=Katel Puspalal , Pinkaew Bannapuch , Talek Kanokporn , Tantilipikorn Pongsakorn 

TITLE=Pattern of Aeroallergen Sensitization and Quality of Life in Adult Thai Patients With Allergic Rhinitis

JOURNAL=Frontiers in Allergy

VOLUME=Volume 2 - 2021

YEAR=2021

URL=https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2021.695055

DOI=10.3389/falgy.2021.695055

ISSN=2673-6101

ABSTRACT=The prevalence of allergic rhinitis (AR) is steadily rising in the Thai population, causing a major impact on the quality of life (QoL). Enhancing knowledge on common aeroallergens in the local setting helps in the appropriate prevention and management of AR. In this study, the demographic characteristics, clinical data, aeroallergen sensitisation pattern, allergic symptoms, VAS score, and QoL are described. We evaluated the association between visual analogue scale (VAS), QoL, and severity of symptoms. We retrospectively reviewed the medical records of adult AR patients with a positive skin prick test for at least one aeroallergen from January 2018 to June 2020. Standard descriptive and inferential statistics were used for analysis. A total of 366 patients were enrolled. Indoor aeroallergen sensitisation and outdoor aeroallergen sensitisation were observed in 32% and 7.9% of patients, respectively. Mono-sensitisation was noted in 16.9% of patients, while poly-sensitisation was noted in 83.1% of patients. Mites (65%) and sedge (39.3%) were the most common indoor and outdoor allergens. Nasal obstruction (74.6%), runny nose (63.7%) and nasal itchiness (61.5%) were the primary symptoms affecting the QoL. The association between VAS and symptom scores showed a trend of association with AR severity (Allergic Rhinitis and its Impact on Asthma [ARIA] classification) and VAS. AR has a significant effect on QoL in all domains of the validated generic (SF-36) and specific (Rcq-36) questionnaires. Mite and sedge remain the most common indoor and outdoor aeroallergens. The pattern of sensitisation and number of aeroallergens were not associated with AR based on the ARIA guidelines. Meanwhile, patients’ symptoms affected the QoL and VAS scores, which can be used as a quick and reliable tool for monitoring and stepping up or stepping down the treatment according to the next-generation guidelines. AR has a significant impact on the QoL of adult Thai patients.