AUTHOR=Scadding G. K. , McDonald M. , Backer V. , Scadding G. , Bernal-Sprekelsen M. , Conti D. M. , De Corso E. , Diamant Z. , Gray C. , Hopkins C. , Jesenak M. , Johansen P. , Kappen J. , Mullol J. , Price D. , Quirce S. , Reitsma S. , Salmi S. , Senior B. , Thyssen J. P. , Wahn U. , Hellings P. W. 

TITLE=Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1—allergic asthma

JOURNAL=Frontiers in Allergy

VOLUME=Volume 4 - 2023

YEAR=2024

URL=https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2023.1291185

DOI=10.3389/falgy.2023.1291185

ISSN=2673-6101

ABSTRACT=Several chronic diseases only become symptomatic from the moment a certain threshold of inflammation or volume of tissue damage has been reached (1-4). By this stage the disease may be irreversible with no possibility of cure (5,6). Recently the idea of earlier pre-emptive diagnosis has evolved. For example, the concept of pre-diabetes has led to identification of likely future diabetics and provision of measures to reduce disease progression. Similarly, the pre-diagnostic phase of Alzheimer’s and Parkinson's diseases are being explored in population-based studies.
In this paper we explore the possibilities for similar action in asthma.