AUTHOR=Proper Steven P. , Dwyer Alexander T. , Appiagyei Andrews , Felton Jennifer M. , Ben-Baruch Morgenstern Netali , Marlman Justin M. , Kotliar Michael , Barski Artem , Troutman Ty D. , Rothenberg Marc E. , Mersha Tesfaye B. , Azouz Nurit P. 

TITLE=Aryl hydrocarbon receptor and IL-13 signaling crosstalk in human keratinocytes and atopic dermatitis

JOURNAL=Frontiers in Allergy

VOLUME=Volume 5 - 2024

YEAR=2024

URL=https://www.frontiersin.org/journals/allergy/articles/10.3389/falgy.2024.1323405

DOI=10.3389/falgy.2024.1323405

ISSN=2673-6101

ABSTRACT=AD atopic dermatitis AHR aryl hydrocarbon receptor DEG differentially expressed gene DMSO dimethylsulfoxide EGFR epidermal growth factor receptor FICZ 6-formyl-indolo[3,2-b]carbazole H3K27ac histone 3 lysine 27 acetylation IL interleukin KC keratinocyte NRF2 nuclear factor erythroid 2-related factor 2 PCA principal component analysis PCB polychlorinated biphenyl PPI proton pump inhibitor scRNAseq single-cell RNA sequencing STAT6 signal transducer and activator of transcription 6 TCDD 2,3,7,8-tetrachlorodibenzo-p-dioxin Th2 T helper type 2