AUTHOR=Sreedharan Jithin K. , Saleh Fred , Alqahtani Abdullah , Albalawi Ibrahim Ahmed , Gopalakrishnan Gokul Krishna , Alahmed Hadi Abdullah , Alsultan Basem Ahmed , Alalharith Dhafer Mana , Alnasser Musallam , Alahmari Ayedh Dafer , Karthika Manjush TITLE=Applications of artificial intelligence in emergency and critical care diagnostics: a systematic review and meta-analysis JOURNAL=Frontiers in Artificial Intelligence VOLUME=Volume 7 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/artificial-intelligence/articles/10.3389/frai.2024.1422551 DOI=10.3389/frai.2024.1422551 ISSN=2624-8212 ABSTRACT=IntroductionArtificial intelligence has come to be the highlight in almost all fields of science. It uses various models and algorithms to detect patterns and specific findings to diagnose a disease with utmost accuracy. With the increasing need for accurate and precise diagnosis of disease, employing artificial intelligence models and concepts in healthcare setup can be beneficial.MethodologyThe search engines and databases employed in this study are PubMed, ScienceDirect and Medline. Studies published between 1st January 2013 to 1st February 2023 were included in this analysis. The selected articles were screened preliminarily using the Rayyan web tool, after which investigators screened the selected articles individually. The risk of bias for the selected studies was assessed using QUADAS-2 tool specially designed to test bias among studies related to diagnostic test reviews.ResultsIn this review, 17 studies were included from a total of 12,173 studies. These studies were analysed for their sensitivity, accuracy, positive predictive value, specificity and negative predictive value in diagnosing barrette’s neoplasia, cardiac arrest, esophageal adenocarcinoma, sepsis and gastrointestinal stromal tumors. All the studies reported heterogeneity with p-value <0.05 at confidence interval 95%.ConclusionThe existing evidential data suggests that artificial intelligence can be highly helpful in the field of diagnosis providing maximum precision and early detection. This helps to prevent disease progression and also helps to provide treatment at the earliest. Employing artificial intelligence in diagnosis will define the advancement of health care environment and also be beneficial in every aspect concerned with treatment to illnesses.